Vaco-Pola2 Vacopharm medicine for allergic runny nose, rhinitis (2 blisters x 15 tablets)

Dosage form Tablet
Specifications Box of 2 blisters x 15 tablets
Ingredient Dexclorpheniramin maleat

Ingredient

Composition information	Content
Dexclorpheniramin maleat	2mg

Uses

Indications

Vaco-Pola 2 indicated in the following cases:

Treatment of allergic runny nose, rhinitis (season or year -round).

Pharmacy

dexclorpheniramine is an antihistamine with very little sedative effects, has side effects against acetylcholine secretion, but this effect is much different between individuals. The antihistamine effect of dexclorpheniramine through the block of the h1 receptor of the acting cells.

pharmacokinetic

absorption:

Dexclorpheniramin Maleat absorbs well through the gastrointestinal tract, the semi -cancellation time in plasma from 30 minutes to 1 hour. Plasma peak concentration is about 2.5 to 6 hours after drinking.

Distribution:

Low bioavailability, reaching 25-50%. About 70% of the drug during the circulation associated with the protein. The distribution volume is about 3.5 liters/kg for adults.

Metabolism:

dexclorpheniramin metabolizes fast and high.

Era:

The drug is excreted mainly in urine in a constant or metabolic form, the excretion depends on the pH and the urine flow. The sale time is 12 - 15 hours.

Before taking Vaco-Pola2 Vacopharm medicine for allergic runny nose, rhinitis (2 blisters x 15 tablets)

How to use

Oral drugs.

Dosage

Adults and children over 12 years: take 1 tablet/time, 3-4 times a day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Symptoms of overdose:

Sediment, inverse stimulation often central nervous system, mental rebellion, seizure, apnea, convulsions, anti -secretion effects Acetylcholin, hypertonic reaction and cardiovascular collapse, arrhythmia.

How to handle:

Treatment of symptoms and supporting life function, especially paying special attention to liver, kidney, respiratory, heart and water balance, electrolyte.

Gastric or vomiting with ipeca syrup. Then, for active carbon and bleach to limit absorption.

When experiencing hypotension and arrhythmia, it should be actively treated. It is possible to treat convulsions by intravenously diazepam or phenytoin. May have to be blood transfusion in heavy cases.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Vaco-Pola 2 , you may experience unwanted effects (ADR).

Common, ADR> 1/100

No report.

Uncommon, 1/1000

No report.

Rare, ADR

Blood and lymphatic system: granulocytosis, leukopenia, Anemia hemolytic.

Nervous system: Foreign tower reaction, tremor, difficulty sleeping, paresthesia.

Mental system: Depression, Lu.

Body: Sweat, hair loss .

Muscle system and connective tissue: muscle pain, convulsions.

ears: tinnitus. blood vessels: Hypotenem pressure.

Not determined frequency

Body: Fatigue.

Nervous system: headache, mental loss, drowsiness, dizziness, loss of movement air conditioning.

Digestive system: dry mouth, dryness of the respiratory tract, constipation, increased gastroesophageal reflux, nausea, vomiting, diarrhea, epigastric pain.

eyes: blurred vision.

Urinary system: Difficult or urinary retention.

Cardiovascular system: suspense, arrhythmia.

Blood vessels: Flushing, hypersensitivity reactions such as bronchospasm, angioedema. The immune system: Anaphylaxis, cross -reaction with other antihistamines.

Skin and subcutaneous tissue: Peeling dermatitis.

Instructions on how to handle ADR:

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Vaco-Pola 2

Hypersensitivity to the composition of the drug.

Patients at risk of closed angle glaucoma.

Patients at risk of urinary retention due to urethral and prostate disorders.

Children under 12 years old.

Pregnant and lactating women.
Caution when using

The elderly is likely to have high blood pressure, dizziness, drowsiness, chronic constipation, prostate swelling.
Patients with liver failure, severe renal failure due to the risk of drug accumulation.
Absolutely do not drink alcohol or alcohol -containing drugs.
The ability to drive and operate machinery

The drug has a sedative effect, not used for drivers and machinery operators.
Pregnancy

only used for pregnant people when really necessary. Using drugs in the last 3 months of pregnancy can lead to serious reactions (such as epilepsy) in infants.
Breastfeeding period

The drug can be secreted through breast milk and inhibit milk. Because antihistamine drugs can cause serious reactions to breastfed babies, it is necessary to consider or not breastfeed or do not take the drug, depending on the level of the medication for the mother.
Drug interaction

Increases the sedative effects of central neurological inhibitors including alcohol, barbituric, sleeping pills, addictive pain, anxiety and anti -psychotic.
Increased anti -muscarin effect when combined with Muscarin anti -anti -Muscarin drugs such as atropin and some antidepressants (both 3 rounds and IMAO).
Can obscure dangerous signs caused by drugs that are harmful to the ears such as aminoglycoside antibiotics.
can hinder skin reactions to allergens and stop taking the drug a few days before doing skin tests.

Storage

To be dry, cool, avoid light, temperature below 30⁰C.

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