VasPycar 20mg Pymepharco medicine for stable angina treatment (2 blisters x 30 tablets)

Dosage form Box of 2 blisters x 30 tablets
Specifications Trimetazidine

Ingredient

Composition information	Content
Trimetazidine	20mg

Uses

Indications

vaspycar 20 mg is indicated in the following cases:

appoint adults in supplementary therapy/support for existing treatment to treat symptoms in patients stable angina unstable, or non -tolerant patients with other angina therapy.

trimetazidin inhibits the oxidation of fatty acids by inhibiting the 3-ketoacyl-coa thiolase enzymes in ischemic cells, energy obtained during glucose oxidation is less than oxygen consumption than oxidative beta. The promotion of glucose oxidation will help optimize cell energy processes, which maintains appropriate energy metabolism during anemia.

Pharmacological effect

In patients with ischemic heart anemia, trimetazidine acts as a metabolite, which helps conserve high intra -intra -intra -intra -intra -intracellular energy levels in myocardial cell. Trimetazidin has anti -anemia effect but does not affect hemodynamics.

Dynamic pharmacokinetics

Relative bioavailability> 85%. After taking trimetazidin, it is quickly absorbed through the digestive system. The maximum concentration in plasma is achieved after about 2 hours. The maximum concentration in plasma is about 85 ng/ml when using a single dose of 40 mg, and reaches 55 ng/ml when taking the only dose of 20 mg. The equilibrium achieved from 24 - 36 hours after taking repeated doses and very stable during treatment.

trimetazidin binds to plasma proteins at a low level of 21%.

DISTRIBUTION OF DISTRIBUTION 4.8 I/KG, ensuring good distribution to tissues.

t1/2 average 6 hours. Trimetazidin is mainly eliminated in urine in constant form.

Before taking VasPycar 20mg Pymepharco medicine for stable angina treatment (2 blisters x 30 tablets)

How to use

oral medication.

Dosage

Adults

A tablet of 20 mg/time x 3 times/day, with meals.

Patients with average renal failure (Creatinine clearance 30 - 60 ml/minute)

Dosage recommended is 1 tablet 20 mg 2 times/day, morning and evening, with meals.

Elderly patients

Elderly patients may have a higher level of trimetazidine sensitivity than normal due to age -old impaired impairment.

Be careful when calculating the dose for elderly patients.

Children

Safety and effectiveness of trimetazidin for patients under 18 years of age has not been evaluated. There is currently no data on this patient object.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when using overdose?

In case of overdose use should be used with drugs such as gastric lavage and use methods to support the total status.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using vaspycar 20 pills , you may experience unwanted effects (ADR).

Common, ADR> 1/100

Body: Dizziness, headache , weakness.

Skin: rash, itching, urticaria.

Disorders on the heart: Brushing chest drum, suspense, extra systolic, fast heartbeat.

Disorders on the nervous system: Symptoms Parkinson (Run, slow and difficult exercise, increase muscle tone), unstable gait, vacuum syndrome, other relevant movement disorders, often recover after stopping the drug. Sleep disorders (insomnia, drowsiness).

Disorders on the stomach - intestines: constipation.

Disorders on the skin and subcutaneous tissue: Excellent pustules (AGEP), Evaluation.

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

vaspycar medicine 20 Contraindications in the following cases:

Hypersensitivity to the active ingredient or any excipient is listed in the product formula.

Be cautious when used

Do not take the drug to treat angina or treatment that starts angina unstable. Not used to treat myocardial infarction.

Do not take the drug in the pre -hospitalization period as well as in the first days of hospitalization.

In case of angina pain , coronary disease should be re -evaluated and considering the appropriate treatment.

Do not use drugs in pregnant and lactating women.

Trimetazidin can cause or worsen Parkinson's symptoms (tremor, slow and difficult exercise, increase muscle tone), so patients, especially elderly patients, need regular check and monitor. In suspicious cases, patients need to be taken to neurologists for appropriate examination.

When encountering movement disorders such as Parkinson's symptoms, irritability, tremor, unsteady gaits immediately stop using trimetazidin.

These cases are rarely occurring and often recover after stopping the drug. Most patients recover after stopping the drug for about 4 months. If Parkinson's symptoms continue to happen for more than 4 months after stopping the drug, consulting neurologists.

may have a self, unstable gait or hypotension, especially in patients who are taking drugs to treat hypertension.

Be careful when prescribing trimetazidin for patients with high sensitivity levels such as:

Patients with average renal impairment.

Patients over 75 years old.

The ability to drive and operate machinery

trimetazidin can cause symptoms such as dizziness and drowsiness, so it can affect the ability to drive and operate machinery.

Pregnancy

should not use drugs in pregnant women.

Breastfeeding period

should not use drugs in nursing women.

Interactive drug

should not be used in combination with imao drugs. There is no interaction with other drugs recorded.

Storage

In a dry, cool place (under 30 ° C). Avoid light.

Other drugs

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