VASTEC DHG medicine treats stable angina (2 blisters x 30 tablets)

Dosage form Box of 2 blisters x 30 tablets
Specifications Trimetazidine

Ingredient

Composition information	Content
Trimetazidine	20mg

Uses

Indications

appoint adults in supplementary therapy/support for existing treatments to treat symptoms in stable angina patients with adequate control or non -tolerated patients with other angina therapy.

Pharmacokology

trimetazidin inhibits the oxidation of fatty acids by inhibiting the 3-ketoacyl-coa thiolase enzymes in ischemic cells, energy obtained during glucose oxidation needs to be less than oxygen than oxidative beta. Promoting glucose oxidation will help optimize cell energy processes, thus maintaining appropriate energy metabolism during anemia.

Effect of learning:

In patients with ischemic heart anemia, trimetazidine acts as a metabolite, which helps conserve high intra -intra -intra -intra -intra -intracellular energy levels in myocardial cell. Trimetazidin has anti -anemia effect but does not affect hemodynamics.

pharmacokinetics

trimetazidin when taken is absorbed very quickly and reaches the peak concentration in plasma before 2 hours from drinking. The equilibrium of the drug in the blood is reached from 24 to 36 hours after repeating a dose and is very stable during treatment. Trimetazidin's waste sale time is 6 hours. The drug is eliminated in the urine in the form of unchanged.

Before taking VASTEC DHG medicine treats stable angina (2 blisters x 30 tablets)

How to use

Take oral, use with meals.

Dosage

A tablet of 20 mg/ time x 3 times/ day, with meals.

Special subjects:

Patients with average renal impairment (Creatinine clearance [30-60 ml/ min): recommended dose is 1 tablet 20 mg/ time x 2 times/ day, morning and evening, use with meals.

Elderly patients. Elderly patients may have a higher level of trimetazidine sensitivity than normal due to the decline in kidney function by age. For patients with average renal impairment (creatinine clearance [30-60 ml/ min), the recommended dose is 1 tablet of 20 mg/ time x 2 times/ day, morning and evening, use with meals. Be careful when calculating the dose for elderly patients.

Children: The safety and effectiveness of trimetazidin for patients under 18 years of age has not been evaluated.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when using overdose?

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using VASTEC 20 mg you may experience unwanted effects (ADR).

Common, ADR> 1/100

Disorders on the nervous system: dizziness, headache;

Disorders on the stomach - intestines: abdominal pain, diarrhea, indigestion, nausea and vomiting;

Disorders on the skin and subcutaneous tissue: rash, itching, urticaria;

Systemic disorders: weakness.

Rare, ADR

Disorders on the heart: Brushing chest drum, nervousness, extra mind, heartbeat;

Pentrlower disorders: arterial hypotension, hypotension, can lead to discomfort, dizziness or falling, flushing.

Unknown frequency:

Sleep disorders: insomnia, drowsiness;

Disorders on the nervous system: Parkinson symptoms (Run, slow movement and difficulty, muscle tone), unstable gait, vacuum syndrome, other relevant movement disorders;

Stomach -intestinal disorders: constipation;

Disorders on the skin and subcutaneous tissue: External pustules (AGEP), Evaluation;

Blood disorders and lymphatic systems: granulocytosis, thrombocytopenic reduction, hemorrhage decreased in arnd;

Hepatitis: Hepatitis.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindications:

Vastec 20 mg contraindicated in the following cases:

Too hypersensitivity to the active ingredient or any excipient is listed in the formula of product preparation.

Parkinson patient, Parkinson's symptoms, tremor, vacuum syndrome and other relevant movement disorders.

Severe renal failure (Creatinine clearance

Be cautious when using

trimetazidin can cause or worsen Parkinson's symptoms (Run, slow exercise and difficulty, increase muscle tone), so patients, especially elderly patients need regular checks and monitoring.

In suspected cases, patients need to be taken to neurologists for appropriate examination. When encountering movement disorders such as Parkinson's symptoms, feet syndrome, tremor, unstable gait, it is necessary to immediately stop using trimetazidin.

These cases are rarely occurring and often recover after stopping the drug. Most patients recover after stopping the drug about 4 months.

If Parkinson's symptoms continue to occur for more than 4 months after taking the drug, consulting neurologists. Selfs may be encountered, unstable gait or hypotension, especially in patients who are taking drugs to treat hypertension.

Be careful when prescribing Trimetazidin for patients with high sensitivity levels such as: Patients with average renal impairment, patients over 75 years old.

The ability to drive and operate machinery

trimetazidin can cause symptoms such as dizziness and drowsiness, so it can affect the ability to drive and operate machinery.

Pregnancy

should not use drugs because there is no clinical research fully proving pregnant women's safety drugs.

breastfeeding period

should not be used for breastfeeding women.

Interactive drug

There has been no interaction with any drug. However, it is still necessary to be careful to monitor when coordinated with another drug.

Storage

In a dry place, the temperature does not exceed 30 ° C, avoiding light.

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