Vedanal Fort Merap skin topical supports the treatment of atopic dermatitis, contact dermatitis (10g)

Dosage form Box of 1 tube
Specifications Fusidic acid, hydrocortisone acetate

Ingredient

Composition information	Content
Acid fusidic	200mg
Hydrocortisone acetate	100mg

Uses

Indications

Vedanal Fort cream is indicated in the treatment of dermatitis, including atopic dermatitis and contact dermatitis, suspected bacterial infections or sensitive to fusidic acid.

Due to Hydrocortison, Vedanal Fort cream is especially suitable in cases where Corticos- Teroid needs weak-acting, including facial dermatitis and children's skin, Vedanal Fort is suitable when used in the face and hands in terms of aesthetics and convenience when used in armpits and groin and skin folds.

Pharmacokology

Medical therapy group: corticosteroid, weak, combined with antibiotics

ATC code: d07ca01

Vedanal Fort combines antibacterial effects of fusidic acid with anti -inflammatory and itching effect of hydrocorti - Sone acetate.

Fusidic acid is an antibiotic with steroid structure, belonging to the fusidanin group, which has bactericidal and bactericidal effects, mainly acting on gram -positive bacteria.

Mechanism of action

Fusidic acid inhibits protein synthetic bacteria through inhibiting an essential factor for the transfer of peptid supplementary units and extending the peptide chain. Although fusidic acid has the ability to inhibit protein synthesis in mammal cells, due to the ability to penetrate poorly into the host cell, the drug works to select against sensitive bacteria.

Hydrocortisone is corticoid secreted from the adrenal gland of the glucocorticoid group that has anti -inflammatory, allergic, anti -itching and immunosuppressive effects.

antibacterial spectrum

Fusidic acid works well on staphylococus strains, especially S. Aureus and S. Epidermidis (including methicillin -resistant strains), Nocardia Asteroides and many Clostridium strains are also very sensitive to drugs. Streptococus and Enterococcus IT strains are more sensitive. Fusidic acid concentration 0.03-0.12 mcg/ml inhibits almost all staphylococcus aureus strains.

Most Gram-negative strains are not sensitive to fusidic acid, but good effects on Neisseria spp. The drug has no effect on mushrooms.

drug resistance

Anti -drug can appear in common strains sensitive to fusidic acid of chromosomes. The high rate of anti -drug anti -drug mutations. So far, it has not been seen against other antibiotics. Fusidic acid is very prone to drug resistance, so it needs to be combined with other antibiotics.

pharmacokinetics

In In vitro studies show that fusidic acid can be absorbed through the skin intact. The level of penetration depends on factors such as the time of exposure to fusidic acid and skin condition. Fusidic acid is excreted mainly in bile, very little excretion through urine.

Hydrocortisone is absorbed after applying on the spot. The level of absorption depends on many factors including skin condition and topical position. The amount of hydrocortisone has been quickly transformed and excreted in the urine.

Before taking Vedanal Fort Merap skin topical supports the treatment of atopic dermatitis, contact dermatitis (10g)

How to use

Vedanal Fort is only topical. Do not swallow. Do not apply to the eyes and mucosa.

Remove the lid, check the seals intact before using the drug for the first time. Then, turn the plastic lid and press the lid strongly into the seal.

Wash your hands before using the drug. Apply gently on the skin to be treated. If using the drug on the face, avoid applying the drug.

Wash your hands after using the drug, unless the drug is used in the hands.

If you accidentally stick to your eyes, rinse with cold water immediately. After that, wash your eyes with eye -catching eye -catching eye, throbbing pain may occur. If you have any vision or eye pain, please contact the doctor immediately.

Dosage

Apply a thin amount of cream to the skin 2 times/day, morning and evening. If the topical skin is covered with the drug, the number of topical applications may be reduced to

Treatment time

The usual treatment time is within 2 weeks. Symptoms of the skin will improve after a few days of cream use. If the symptoms do not improve after 7 days, it is necessary to stop using and contact the doctor.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? Cushing and adrenal insufficiency syndrome can grow after applying corticosteroids in large quantities and for more than 3 weeks. When accidentally swallowed the cream, the overdose of the active ingredients on the whole body is not likely to occur. The total mass of Fusidic acid in a vedanal Fort is usually not exceeding the daily dosage in the body treatment. Single -dose corticosteroid overdose is rare for clinical problems.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

The most unwanted effects in the treatment process are: different skin reactions such as itching, rash, pain and discomfort at the top of the drug

The unwanted effect is listed below by organ and frequency. The frequency is determined as follows: Very common (≥ 1/10), common (≥ 1/100 to In each frequency group, unwanted effects are presented in the order of severe severity.

Immune system disorders:

Uncommon: Hypersensitivity reaction.

Skin disorders and subcutaneous tissues:

Uncommon: Dermatitis (including contact dermatitis, eczema), rash (erythema, pustules, blisters, small skin acne, general rash), itching, erythema.

Common: irritation and pain at the topical position (including skin burning).

Interior pressure and glaucoma can also occur after applying corticosteroids in the skin near the eyes, especially when used for prolonged use and in patients prone to progressive glaucoma.

Unwanted effects on the skin of mild corticosteroids such as hydrocortison include: Skin atrophy, dermatitis (including contact dermatitis, acne -like dermatitis and dermatitis around the mouth), stretch marks, capillary dilatation, red acne, skin redness, hemorrhoids, and sweating. Bloody can also occur when using local corticosteroids.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Vedanal Fort is contraindicated in the following cases:

Patients with a history of allergies to fusidic acid, hydrocortisone acetate or any ingredients of the drug.

Precautions when using

avoid long -term medication continuously.

Depending on the location of the drug, the whole body absorption of hydrocortisone acetate should be considered during treatment.

Due to the ingredient containing corticosteroids, the drug should be carefully used the area near the eye. Avoid sticking to the eye.

The reverse inhibition of the hypothalamus-Yen-Theme (HPA) can occur after the body absorption of corticosteroids topical skin with or not using closed measures.

Be cautious when taking drugs in children because corticosteroids topical skin in children can inhibit the HPA axis and more Cushing syndrome in adults due to more sensitivity. There have been reports on drug resistance of staphylococ - cus aureus when using 2% fusidic acid on the spot. As with all antibiotics, prolonged or repeated use may increase the risk of drug resistance. Limit treatment time with topical form of fusidic acid and hydrogen - cortisone acetate will not exceed 14 days will reduce the risk of drug resistance.

The limit of treatment also prevents the risks caused by the immunosuppressive effect of corticosteroids that can hide any of the hidden symptoms of infections caused by antibiotic -resistant bacteria. Combining antibiotics - steroids should not last more than 7 days if clinical symptoms are not improved.

Due to the immunosuppressive effect of corticosteroids, Vedanal Fort is at risk of increasing bacterial infections, making the available bacterial infections worse and potential bacterial infections. If infections cannot be controlled with topical medication, it is advisable to switch to systemic treatment.

Vedanal Fort contains corticosteroids, not recommended in the following cases: Skin atrophy, skin ulcers, regular acne, shallow veins, itching around the anus and genitals. Avoid exposure to open wounds and mucous membranes. As with all corticosteroids, avoid prolonged use on the face.

Using drugs for women during pregnancy and lactation

Pregnant women

There is no clinical data on the use of fusidic acid/ sodium fusidate in pregnant women. Exposure to the body when applying on the skin of Fusidic acid/sodium fusidate is negligible.

Corticosteroids should not be widely used, used in large quantities and long -term use in pregnant women due to abnormalities that have been detected on animals due to systemic absorption drugs.

Only use Vedanal Fort during pregnancy when really necessary.

breastfeeding women

Do not observe the effect on breastfeeding because the body absorption when applying Fusidic acid/hydrocortosone acetate on a narrow range in nursing women is negligible. Vedanal Fort can be used in breastfeeding women, avoiding topics on the chest.

The effect of the drug on driving and operating machinery

Vedanal Fort skin cream does not have a significant impact or a significant impact on the ability to drive and operate machinery.

Medicine interaction

Interactions of topical type of skin has not been conducted. Interaction with drugs when using systemic sugar is very small because the whole body absorption when applying Vedanal Fort is negligible.

Check Dopping: Athletes must not use corticosteroids except for creams/fats/topical solutions. If using topical topical medications containing CortiIDOID, athletes need to write a note (y) before participating in the competition.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

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