Venrutine 500mg/100mg BRV treat hemorrhoids, subcutaneous hemorrhage (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Rutin, vitamin C

Ingredient

Composition information	Content
Rutin	500mg
Vitamin C

Uses

Indications

Venrutine drugs are indicated in the following cases:

Treatment of hemorrhoids.

rutin

Also known as rutosid is a flavonol glycosides made up of flavonol quercetin and disacarid rutinose extracted from rich medicinal herbs such as flower buds, pulse, orange, lemon, chili or from some Eucalyptus species.

rutin has the effect of enhancing endurance and reducing capillary permeability, anti -inflammatory, anti -edema protecting blood vessels. The main mechanism of action is to inhibit the compatibility with Catecholamin-0-Methyltransferase to prevent oxidation from destroying adrenalin during circulation (Adrenalin has the effect of increasing capillary endurance). Anti -inflammatory effects may be due to adrenal stimulation adrenalin secretion and hyaluronidase inhibitors.

In addition, rutin also has antioxidant effects, tumor anti -tumors, anti -thrombosis, hypotension, cholesterol lowering, reducing the risk of cerebral hemorrhage and hemostasis.

vitamin C (ascorbic acid)

Needed for collagen creation, tissue repair in the body and participate in oxidation - reduction reactions, enhance the immune system, in resistance to infections. In addition, Vitamin C is also a strong oxidative substance and has a special role in keeping the integrity of the blood vessels especially the capillaries and this effect is enhanced by rutin.

pharmacokinetic

absorption

Vitamin C is easily absorbed after drinking. However, absorption is a positive process and may be limited after huge doses. In normal human research, only 50% of a dose of 1.5 g vitamin C is absorbed. Absorption of vitamin C in the stomach - intestines can be reduced in diarrhea or gastric disease.

Normal vitamin C concentration in plasma is about 10 - 20 micrograms/ml.

Storage of all vitamin C in the body is estimated at 1.5 g with about 30 - 45 mg daily rotation.

Clinical signs of Scorbut disease often become clear after 3-5 months of vitamin C deficiency.

Distribution

Vitamin C is widely distributed in body tissues. About 25% of vitamin C in plasma combined with protein.

Elimination

Vitamin C has reversible oxidation into dehydroorscorbic acid.

A little vitamin C converted into non-activity compounds including ascorbic acid-2-sulfate and oxalic acid excreted in urine.

The amount of vitamin C exceeding the needs of the body is also quickly excreted into urine in the form of unchanged. This usually occurs when the daily amount of vitamin C is exceeded 200 mg.

Before taking Venrutine 500mg/100mg BRV treat hemorrhoids, subcutaneous hemorrhage (3 blisters x 10 tablets)

How to use

Venrutine drugs are used by oral.

Dosage

Adults: take 1 tablet, 1-2 times daily.

Children from 6 years old: take 1/2 tablets, 1-2 times daily.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Overdose rutin

rarely occurs, overdose symptoms include: dizziness, fatigue, headache, muscle stiffness, fast heart rate, discomfort in the stomach.

Exodus vitamin C

Includes symptoms such as kidney stones, nausea, gastritis and diuretic diarrhea by infusion that can work after large dose.

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Venrutine, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Gastrointestinal disorders, nausea, rarely have headaches, pagoda.

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

VENRUTINE medicine is contraindicated in the following cases:

Hypersensitivity to rutin or one of the ingredients of the drug.

Be cautious when used

High doses of vitamin C (over 3 g/day) can cause oxalate or urate ureter.

Use cautious for people with gastrointestinal ulcer.

The ability to drive and operate machinery

The drug does not affect driving and operating machinery.

Pregnancy

Use caution drugs for pregnant women.

Breastfeeding period

Drug interaction

Avoid antibiotics with quinolones because according to the theory of quercetin formed from rutin competition inhibitors on DNA-GYRASE receptors reduces the effect of quinolin.

Because vitamin C contains vitamin C can increase the absorption of iron through the gastrointestinal tract.

Use vitamin C at the same time with aspirin reducing aspirin secretion and increased vitamin C excretion.

Use vitamin C at the same time with fluhenazin reduces the levels of fluphenazin in plasma.

During the use of rutin -containing drugs, there should be many processed foods that contain nitrate and nitrite because there is an idea that rutin may be nitrogen -produced to create mutant potential substances.

Storage

The temperature does not exceed 30 ° C, avoiding light and moisture.

Other drugs

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