Vincozyn plus Vinphaco solution prevents and treats vitamin B deficiency diseases (2 blisters x 5 tubes x 2ml)

Dosage form Box of 2 blisters x 5 tubes
Specifications Vitamin B1

Ingredient

Composition informationContent
Vitamin B110mg

Uses

Indications

Vincozyn plus injection is used to prevent and treat B vitamin deficiency diseases in the case of completely nourishing on the gastrointestinal tract.

Pharmacokology

Related to vitamin B1:

  • Thiamin combined with Adenosin Triphosphate (ATP) in the liver, kidneys and leukocytes to form a thiamin diphosphate form (Thiamin pyrophosphate) with physiological activity. Pyruvat and Alpha - Cetoglutarat and in using pentose in the Hexose Monophosphate cycle.
  • Riboflavin after entering the body is transformed into 2 coenzymes, Flavin Mononucleotid (FMN) and Flavin Adenin Dinucleotid (FAD), which are the forms of active coenzyme for tissue respiration. Overcoming the integrity of red blood cells.
  • In the body, nicotinamid converts to nicotinamid adenin dinucleotid (NAD) and Nicotinamid adenin Dinucleotid phosphate (NADP). Lipid metabolism. Among these reactions, these coenzymes work as hydrogen transport molecules.
  • When entering the body, pyridoxin transforms into pyridoxal phosphate and partly into pyridoxamin phosphate. Pyridoxin participates in the synthesis of gamma acid - Aminobutyric (GABA) in the central nervous system and participates in the synthesis of hemoglobulin.
  • Dexpanthenol is converted into pantothenic acid, which corresponds to the foreign group of Coenzym A (Lipmann), which is the main factor in the Krebs cycle. The development, epithelium and growth of nails and hair.
  • Thiamin is allocated widely into the tissues in the body and is distributed in breast milk.
  • riboflavin is absorbed mainly in the duodenum. Water, quickly excreted through the kidneys. The amount of putting in excess of the need for the body will be discharged in the form of unchanged urine.
  • Nicotinamid is widely distributed into the body tissue. Nicotinuric. However, when using large doses, the amount of excretion in the form of unchanged will increase.

    • Related to vitamin B6:

  • In the body, pyridoxin transforms into pyridoxal phosphate and pyridoxamin phosphate and most reserves in the liver and part of the muscles and brain.

    Related to vitamin B5:

  • After the injection, the drug is absorbed quickly, distributed to the tissue in the body, excreting through the kidneys.

    • Before taking Vincozyn plus Vinphaco solution prevents and treats vitamin B deficiency diseases (2 blisters x 5 tubes x 2ml)

    How to use

    Vincozyn plus injection drug used intramuscular, intravenous or intravenous injection.

    In case of intravenous infusion, Vincozyn Plus should not be mixed with other drugs (due to the lack of correlation of the drug's correlation).

    The solution used to dilute Vincozyn Plus for intravenous injection is 0.9%sodium chloride infusion solution.

    Dosage

    Common dose in adults and the elderly: 1 - 2 tubes/day.

    Children and adolescents: There is no specific recommendation, which should only be used when proving the benefits of superior treatment of the risk caused by the drug. At that time, the dose of the drug as directed by the treating doctor.

    Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when using overdose?

    What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

    Side Effects

    When using Vincozyn Plus injection, you may experience unwanted effects (ADR).

    Related to Vitamin B: Thiamin's ADR is very rare and often allergic. Normally, because Thiamin enhances the effects of acetylcholin, some skin reactions can be considered as a reaction.

    Rare, ADR

  • The whole body: Sweating, hypersensitivity Using high doses of riboflavin urine will turn light yellow, causing deviations for some urine tests in the laboratory.

    Related to vitamin PP: Small doses of vitamin PP are usually not toxic, but if high doses may occur some of the following unwanted effects these unwanted effects will go away after stopping the drug):

    Common, ADR> 1/100:

  • Digestive: Nausea.
  • Digestive: progressive stomach ulcers, vomiting, anorexia, pain when hungry, flatulence, melting.
  • Skin: dry skin, hyperpigmentation, jaundice, rash Fuzzy, dry eyes, swelling of the eyelids, dizziness, heartbeat, fainting, wheezing.

    • Rare, ADR

  • Anxiety, panic, urinary glucose, abnormal liver function (including serum bilirubin, AST (SGOT), ALT (SGPT) and LDH), abnormal prothrombin time, lower blood albumin, traitor. Using pyridoxine lasts for 10 mg/day is said to be safe but used at a dose of 200 mg or more daily can cause neurological diseases.
  • Central nervous system: headache, drowsiness, drowsiness. The feet come to a numbness and clumsy hands. This condition can recover when stopping the drug, although there is still more or less sequelae.
  • Other: allergic reactions.

    • Warnings

    Before using the drug you need to read the instructions carefully and refer to the information below.

    Contraindicated

    Vincozyn plus injection drug is contraindicated in the following cases:

  • Hypersensitivity to any ingredients of the drug.

    Be cautious when using

    need to be very careful when taking the drug for patients in the following cases:

    Related to vitamin B2:

  • The lack of riboflavin often occurs without other B vitamins.

    • Related to vitamin PP:

  • Be cautious when using nicotinamid in high doses for the following cases: History of gastrointestinal ulcer, acute coronary artery syndrome, gallbladder disease, history of jaundice or liver disease, kidney disease, gout, gout arthritis, diabetes.

    • Related to vitamin B6:

  • After a long time of using pyridoxin at a dose of 200 mg/day, a manifestation of neurotoxicity (such as severe peripheral neuropathy and severe sensory neuropathy).

    The ability to drive and operate machinery

    Persons who often drive or operate machinery should use Vincozyn Plus injection?

    The drug can cause vomiting, muscle stiffness, skin itching, hypotension. Therefore, not driving, operating machinery or working on high when encountered unwanted effects of the drug.

    Women during pregnancy and nursing mothers

    Women during pregnancy should use Vincozyn Plus injection?

    The drug can be used for pregnant women.

    Should women breastfeeding should use vincozyn plus injection?

    The drug can be used for breastfeeding women.

    Drug interaction

    drug interactions may affect the activity of the drug or cause side effects. Should notify the doctor or pharmacist a list of drugs and functional foods you are using. Do not use or increase or decrease the dose of the drug without the guidance of a doctor.

    Related to vitamin B1:

  • Thiamin can increase the effects of neurotransmitter.

    • Related to vitamin B2:

  • Meet some "missing riboflavin" cases in people who used clopromazin, imipramin, amitriptylin and adriamycin.

    Related to vitamin PP:

  • Using nicotinamid simultaneously with HGM - CoA reducing enzyme inhibitors can increase the risk of muscle eligibility. Simultaneously with nicotinamid.

    Related to vitamin B6:

  • pyridoxin reduces the effect of levodopa in the treatment of Parkinson's disease, this does not occur with preparations as a mixture of Levodopa - Carbidopa or Levodopa - Benserazid.
  • pyridoxin can lighten depression in women who take birth control pills.

    Related to vitamin B5:

  • Do not use dexpanthenol together or within 12 hours after using Neostigmin or other sympathetic nerve -like effects. Having occurred when using dexpanthenol injection with antibiotics, opiat and barbiturat drugs.

    • Storage

    Leave a cool place, avoid light, temperature below 30⁰C.

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