Vinocyclin 100 Medisun treat acne, respiratory infections (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Minocyclin

Ingredient

Composition information	Content
Minocyclin	100mg

Uses

Indications

Vinocyclin drugs are an antibiotic, which has the same spectrum to act as antibiotics Tetracyclin but more powerful on Staphylococcus aureus and Nocardia spp.

Minocyclin is indicated for treatment in cases such as acne, respiratory infections, gonorrhea, staphylococcal infections and preventive treatment for meningococcal infections.

Pharmacokology

ATC code: J01AA08. Semi -synthetic antibiotics Tetracyclin.

The mechanism of action of minocyclin has a bacterial effect due to inhibiting the synthesis of bacterial proteins by attaching to the 30S part of ribosom, which inhibits the attached aminoucyl-Arny to the reception position.

Minocyclin hydrochlorid has antibacterial spectrum and similar mechanism of effect of tetracyclin hydrochlorid, but has a stronger effect on some bacteria strains, including Staphylococcus aureus, Streptococci, Neisseria Meningitidis, different enterobacteria, acinetobacter, bacterotes, bacterotes, bacterotes, bacterotes, bacterioides Nocardia, and some Mycobacteria bacteria, including M. Leprae. In addition, on in vitro, minocyclin hydrochlorid is reported against some anti -tetracyclin, streptococci and some Escherichia coli strains resistant to tetracyclin and Haemophilus influenzae.

There is a partial diagonal resistance between minocyclin and other tetracyclin but some strains of other drugs in the group are still sensitive to minocyclin, due to the ability to penetrate into the cells of minocyclin better.

Dynamic pharmacokinetics

minocyclin well absorbed through the gastrointestinal tract, almost completely after drinking.

The absorption of minocyclin is not significantly affected by food and milk. The dose of 200 mg per day or 100 mg every 12 hours for plasma concentrations is 1 - 4 mg/ml.

The semi -exhaust time of minocyclin is 12-16 hours in patients with normal renal function, but lasts in patients with impaired renal function.

Minocyclin is widely distributed throughout the entire body and tissues. Minocyclin passes through the placenta fence and is excreted in breast milk.

Before taking Vinocyclin 100 Medisun treat acne, respiratory infections (3 blisters x 10 tablets)

How to use

vinocyclin oral medication.

Dosage

adults:

Using antibiotics regularly: 100 mg/time x 2 times/day.

Acne: 100 mg/time x 1 time/day.

Gonorrhea:

Adult men: 200 mg of initial dose, followed by 100 mg every 12 hours, at least 4 days, implantation of urine check for 2-3 days after stopping the drug. Maintain for 5 days, then often accompanied by a rifampicin treatment.

Children:

Vinocyclin 100 is not recommended for children under 12 years old. For children over 12 years old, the recommended dose is 100 mg/time x 1 time/day.

Old people:

Vinocyclin 100 can be used in the usual dosage for older patients but need to be cautious in patients with renal failure.

acne treatment route with minocyclin should be extended continuously for at least 6 weeks. If after 6 months of treatment, no progress should stop using the drug and consider other treatment. If using minocyclin for 6 months, patients should be monitored at least 3 months after treatment of signs and symptoms of hepatitis or erythema lupus.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Handling: There is no specific overdose treatment. When an overdose occurs, gastrointestinal bowel is combined with symptom support.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using the drug, there are common unwanted effects (ADR) such as:

Agency system frequency Blood rare (≥1/10 000, Incretion of eosinophilia, leukopenia, neutropenia, platelets Yes) grain leukemia Multi -artery inflammation of the button Eat ( heart rare (≥1/10 000, Myocarditis, pericarditis Breathing (≥1/10 000,

diarrhea, nausea, gastritis, tooth discoloration, vomiting

Liver enzyme, hepatitis, hepatoparis toxicity

Gut, esophagitis, esophageal ulcer, tongue inflammation, pancreatitis, fake colitis. Under the skin rare (≥1/10 000, Diverse hair loss, diverse pink rash, pink button, rash due to fixed drugs, hyperpigmentation, sensitivity, itchy inflammation, rash, urticaria, vasculitis. Stevens-Johnson, epidermal necrosis due to poisoning muscle pain, lupus syndrome Increases blood urea, acute renal failure, interstitial nephritis 1/1000) Fever

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Vinocyclin drugs contraindicated in the following cases:

hypersensitively to minocyclin, tetracyclin or any ingredients of the drug.

Be cautious when used

Vinocyclin 100 is used cautiously in patients with liver dysfunction, alcohol use or being used to poison with other liver.

Cross -resistance to tetracyclin can develop microorganisms and increase cross -sensitivity in patients. Minocyclin should be discontinued if there are signs or symptoms of excessive increase in bacterial resistance such as tongue inflammation, stomatitis, vaginitis, itching or staphitis.

Use minocyclin in patients who are taking birth control pills if diarrhea or sudden bleeding, the possibility of contraception is not effective.

Rarely have liver toxicity or acute symptoms of the system that has been reported.

If the patient has signs of systemic lupus erythematosus or liver poisoning, the drug should be stopped. Be careful when using minocyclin with patients with myasthenia gravis. Like tetracyclin, minocyclin can inhibit nerves.

Patients with genetic problems in galactose tolerance, malventia - galactose are not tolerant.

The effect of the drug on the ability to drive and operate machinery

Due to some side effects when using the drug can affect the ability to drive and operate machinery, thus need to be cautious when taking the drug for these objects.

Use drugs for women during pregnancy and lactation

Pregnant women

Do not use minocyclin during pregnancy. Animal research shows that tetracyclin through the placenta and is found in fetal tissue and can be toxic to the fetus associated with bone development.

breastfeeding women

Do not use minocyclin for breastfeeding women.

drug interaction

Because tetracyclin reduces the activity of prothrombin in plasma, patients are being treated with anticoagulant drugs must be reduced anticoagulant dose when used simultaneously with minocyclin.

Do not use minocyclin simultaneously with other penicillin drugs.

antacids and preparations containing aluminum, iron, calcium, magnesium, bismuth or zinc salts reduce the absorption of minocyclin, so do not use simultaneously Vinocyclin 100 with these drugs.

Unused minocyclin with oral contraceptives due to reducing the effectiveness of birth control pills.

Minocyclin used simultaneously with diuretics can increase the toxicity of the kidneys.

Storage

Store at a temperature not exceeding 30 ° C in the original packaging, avoid moisture and avoid light.

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