Vipicetam 800 Hassan medicine treats symptoms of dizziness, stroke (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Piracetam

Ingredient

Composition information	Content
Piracetam	800mg

Uses

Indications

Vipicetam 800mg drug is indicated in the following cases:

Treatment of dizziness symptoms.

In the elderly: memory impairment, dizziness, poor concentration, or lack of alertness, mood change, behavioral disorders, poor attention to yourself, dementia due to high cerebral infarction.

College of ischemic stroke.

Treatment of alcoholism.

Treatment of sickle cell anemia.

Applied use in the treatment of muscle vibration originating from the cerebral cortex regardless of the cause.

Pharmacy

Piracetam (derivatives of Gamma Amino acid - Butyric, GABA) is considered a substance that has a manicular effect (improving the metabolism of neuron cells), although it is not well known about its specific effects as well as its mechanism of action.

Piracetam acts on some neurotransmitters such as acetylcholin, noradrenalin, dopamin, ... This can explain the positive effect of the drug on learning and improve the ability to perform memory tests. The drug can change neurotransmitter and contribute to improving the metabolic environment for good nerve cells.

On experiments, Piracetam has a protective effect against metabolic disorders due to ischemia by increasing brain resistance to oxygen deficiency. Piracetam increases the mobilization and use of glucose without depending on the supply of oxygen, facilitates the pentose path and maintains energy synthesis in the brain. Piracetam enhances the recovery rate after damage due to lack of oxygen by increasing the rotation of inorganic phosphate, reducing glucose accumulation and lactic acid. Under normal conditions as well as when oxygen deficiency, piracetam increases the amount of ATP in the brain due to increased ADP conversion to ATP.

The impact on acetylcholin transmission (increasing the release of acetylcholin) may also contribute to the mechanism of action of the drug. The drug also has the effect of increasing dopamine release and this may have a good effect on memory formation. The drug has no effect on sleep, sedation, resuscitation, pain, sedation as well as no effect of GABA.

Piracetam reduces the ability to conquer platelets and reduce blood viscosity at high doses, in case of abnormal erythrocytes, red blood cells restore deformation ability and capable of passing through capillaries.

The drug has anti -vibration effect and should be used in combination with other anti -vibration therapies.

pharmacokinetic

absorption

Piracetam used by oral is absorbed quickly and almost entirely in the digestive tract. Biology nearly 100%. The peak concentration of plasma (40 - 60ng/ml) appears 30 minutes after taking the dose 2. Absorption of drugs does not change during long -term treatment.

Distribution

The distribution volume is about 0.6L/ kg. Piracetam absorbed into all tissues and can be through the bloody barrier, placenta and membranes used in the kidney. The drug has high concentrations in the cerebral cortex, frontal lobe, top lobe, occipital lobes, cerebellum and base core.

Metabolism

Piracetam is not known to be metabolized in the human body. This lack of metabolism is supported by the long -term semi -cancellation time in malnourished patients and the high recovery ability of the mother compound in the urine.

Elimination

Semi -selling time in plasma is 4-5 hours, in cerebrospinal fluid about 6-8 hours. Piracetam is not attached to plasma proteins and is excreted through the kidneys in the form of intact, 30 hours after drinking, more than 95% of the drug is excreted in urine. Piracetam clearance coefficient of the kidney in normal people is 86ml/ min. If kidney failure, the selling time increases.

Before taking Vipicetam 800 Hassan medicine treats symptoms of dizziness, stroke (10 blisters x 10 tablets)

How to use

Take oral use.

film bags should be swallowed with liquid. Daily dose should be divided into two to four sub -doses.

Dosage

Long -term treatment of physical mental syndrome in the elderly

Use from 1.2 - 2.4g/day. The dose may be high to 4.8g/day in the first weeks.

Action for alcoholism

Use 12g/day for the first week. Maintain drinking from 2 - 4g/day.

A cognitive impairment after brain injury

The first dose is from 9 - 12g/day, the maintenance dose in the following days is 2.4g of medicine, taking at least for 3 consecutive weeks.

People with sickle cell anemia

Use 160mg/kg/day, divided into 4 times evenly.

Support patients with muscle vibration

dose 7.2g/day, divided into 2-3 times.

Depending on the reaction of the body, every 3-4 days increases by 4.8g/day to a maximum dose of 20g/day.

Elderly

Recommendation of the dose adjustment in elderly patients with damaged kidney function.

kidney failure

Daily dose must be personalized depending on the kidney function.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Handling

There is no specific antidote when using Piracetam overdose. Overdose treatment should be treated by symptoms and may include dialysis. Need to manage more according to the clinical indications of the doctor.

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Vipicetam 800mg, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Body: Fatigue.

digestion: Nausea, vomiting, diarrhea, pain and bloating. nerve: restlessness, prone to agitation, headache, insomnia, falling asleep.

Uncommon, 1/1000

Body: Dizziness.

Neurological: trembling, sexual stimulation.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Vipicetam 800mg contraindications in the following cases:

Hypersensitivity to piracetam, other pyrroidone derivatives or any excipients of the drug.

Patients with severe renal impairment (Creatinine clearance coefficient

People with Huntington.

Patients with liver failure.

Precautions when using

should be cautious when taking the drug for patients with renal failure. Need to monitor the kidney function closely when treating this patient and the elderly.

The clearance coefficient of creatinine is below 60ml/minute or serum creatinine above 1.25mg/100ml, the dose adjustment should be adjusted as follows:

Creatinin clearance coefficient: 60 - 40ml/min, serum creatinine: 1.25 - 1.7mg/100ml (half -life of Piracetam is twice as long): Use 1/2 normal dose.

Creatinine clearance coefficient: 40 - 20ml/min, serum creatinine: 1.7 - 3.0mg/100ml (half -life of piracetam is 25 - 42 hours): Using only 1/4 of normal dose.

The ability to drive and operate machinery

The drug can cause drowsiness and trembling. If this happens, do not drive or use machines while using the drug.

Pregnancy

Piracetam can be through the placenta. Piracetam should not be used during pregnancy unless it is necessary, when the benefits beyond the risk and clinical status of pregnant women need to be treated with Piracetam.

Breastfeeding period

Piracetam is excreted through breast milk. Piracetam should not be used during breastfeeding. The decision to stop breastfeeding or stop treatment with Piracetam takes into account the benefits of breastfeeding for the child and the benefits of the treatment of a woman.

Medicinal interaction

thyroid hormone: simultaneously used with piracetam can cause confusion, irritation and sleep disorders.

Anti -epileptic drugs: The daily dose of Piracetam daily for 4 weeks does not change the peak concentration and bottom of the anti -epileptic drug (carbamazepine, phenytoin, phenobarbitone, valproate) in epilepsy patients taking stable dose.

Alcohol: Drinking alcohol does not affect the concentration of piracetam in serum and alcohol levels not changed by the dose of 1.6g piracetam.

warfarin: In a patient, prothrombin time has been stabilized by warfarin again when using piracetam.

Storage

The temperature does not exceed 30 ° C, avoiding light and moisture.

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