Vitamin A 5000 IU MEKOPHAR treat vitamin A deficiency, supplement for people with liver disease (10 blisters x 10 tablets)

Dosage form Hard capsules
Specifications Box of 10 blisters x 10 tablets
Ingredient Vitamin A
Indication Eye fatigue, dry eyes, night blindness

Ingredient

Composition information	Content
Vitamin A	5000iu

Uses

indications

Vitamin A 5000 IU drugs are indicated in the following cases:

Vitamin A deficiency treatment.

Supplement for people with liver disease, especially biliary hepatitis due to reduced absorption and reserves of vitamin A.

Pharmacology

Vitamin A is an oil -soluble vitamin that is essential for vision, growth, development and maintenance of epithelium.

Pharmacokinetics

absorption

The drug absorbs fast and complete if the dose does not exceed the physiological needs and if absorbing normal fat. Inadequate absorption if taken large doses and when absorbing fat, eating low protein or having liver or pancreatic disease.

After taking retinol oil solution, the plasma peak concentration of ester retinol is achieved after about 4-5 hours and 3-4 hours after drinking retinol mixed with water. Plasma concentrations are also higher when using preparations mixed with water of retinol compared to oil preparations. Normal blood retino concentration ranges from 300 - 700 ng/ml in adults and 200 - 500 ng/ml in young children.

Distribution

Retinol is distributed into the body's organizations, the liver is mainly reserved, a small amount is stored in the kidneys, lungs, adrenal glands, retina and fat in the peritoneal. Retinol is released from the liver, attached to Alpha-1-Globulin, protein with retinol (RBP). Vitamin A is distributed into milk, not easy to enter the placenta.

Elimination

Retinol eliminates glucuronide through the kidney and bile. Retinal, retinoic acid and other metabolites dissolve in water, excreted through urine and feces.

Before taking Vitamin A 5000 IU MEKOPHAR treat vitamin A deficiency, supplement for people with liver disease (10 blisters x 10 tablets)

How to use

oral medication.

Dosage

Dosage as directed by the doctor.

Recommended dose in the following cases:

Treatment of vitamin A deficiency: adults and children> 8 years old take 2-4 capsules/day (used as a maintenance dose after being treated for 2 weeks with higher doses).

Supplement for liver disease: Adults over 18 years old take 1 tablet/day continuously for 6 months or 2 consecutive daily tablets for 4 months.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Actively monitor for timely management measures.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using vitamin A 5000 IU, you may experience unwanted effects (ADR).

Neurology: headache, easily stimulated, anorexia.

Gastrointestinal: vomiting, digestive disorders.

liver - bile: liver - spleen enlargement.

Skin and connective tissue: Skin changes, hair loss, crispy dry hair, cracked lips and bleeding, edema under the skin.

Blood: Anemia.

Endocrine and metabolism: high blood calcium.

muscle, bone and connective tissue: Pain in bone and joints.

Body: fatigue, fever, weight loss.

Instructions on how to handle ADR

Notice immediately to the doctor or pharmacist the harmful reactions encountered when using the drug.

Need to stop taking the drug as soon as there are symptoms of unwanted effects.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Vitamin A 5000 IU contraindications in the following cases:

Patients overdose vitamin A.

Be cautious when using

Precautions when using other drugs containing vitamin A.

The ability to drive and operate machinery

has not seen drugs affecting the ability to drive and operate machinery.

Pregnancy

Avoid using vitamin A or synthetic preparations of the same type such as Isotretinoin with high doses for pregnant women because of high doses of vitamin A (10 000 IU/day) capable of teratogenicity.

The period of breastfeeding

vitamin A excreted into breast milk. Women who are breastfeeding do not use more than 1 tablet/day.

Interactive drug

neomycin, cholestyramine, liquid paraffin reduces the absorption of vitamin A. Oral contraceptives can increase vitamin A concentration in plasma.

Vitamin A and Isotretinoin simultaneously can lead to an overdose of vitamin A, so it is necessary to avoid using these two drugs simultaneously.

Orlistat can reduce the absorption of vitamin A, leading to low plasma vitamin A levels in some people.

High doses of vitamin A may increase the effect of reducing the blood prothrombin of warfarin.

Cavalry of the drug: Due to no studies on the correspondence of the drug, not mixing this drug with other drugs.

Storage

Store in a dry place, avoid light, the temperature does not exceed 30 ° C.

Other drugs

Disclaimer

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