Vitamin B1 50mg Nadyphar treats vitamin B1 deficiency (100 tablets)

Dosage form Box of 100 capsules
Specifications Thiamine, vitamin B1

Ingredient

Composition information	Content
Thiamine	50mg
Vitamin B1

Uses

Indications

Vitamin B1 drugs are indicated in the following cases: Treatment of vitamin B1 deficiency diseases, numbness, neuritis, multiple neuritis due to alcoholism.

Pharmacokological

Thiamine pyrophosphate (TPP), Thiamine's coenzymatic form, related to two main metabolic reactions: α-ketoacids and transketolation. Therefore, the main physiological role of Thiamine is a coenzyme in the metabolism of carbohydrates, when TPP is required in a few stages in the decomposition of glucose to provide energy.

In addition to its metabolic role is also a coenzyme, Thiamine plays a role in the nerve transmission function.

In high doses, Thiamine inhibits the transmission of nervous stimulation and therefore can have analgesic effect.

pharmacokinetic

absorption

After drinking, Thiamin is well absorbed. However, at high doses of limited absorption.

Distribution

Thiamin is widely distributed in tissues, and is secreted through breast milk. In cells, Thiamin mainly exists in the form of diphosphate.

Metabolism, excretion

In adults, Thiamin storage is estimated at 30mg and about 1mg of Thiamin is completely struck every day in tissues, this is the minimum amount of daily need. When absorbed at this low level, there are very little or no thiamin excreted through the urine. When absorbed beyond the minimum demand, Thiamin storage in saturated tissues, the emissions through the urine in the form of intact thiamin molecules and metabolized form. When Thiamin's absorption increases further, excretion in the form of untreated thiamin will increase.

Before taking Vitamin B1 50mg Nadyphar treats vitamin B1 deficiency (100 tablets)

How to use

Take oral use.

Dosage

Treatment of edema (Beri - Beri)

Adults

Depending on the condition of severe or mild disease, 30 - 300mg/day is divided into 2-3 times.

Children

Take 1/2 adult dose.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when using overdose?

No report. However, at very high doses, Thiamin can cause headaches, nausea, discomfort, and hypotension.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using vitamin B1, you may experience unwanted effects (ADR).

Very rare and often allergic.

Gastrointestinal disorders: Mild digestive side effects such as nausea, vomiting, diarrhea, and abdominal pain have been reported (unknown frequency).

Disorders of the immune system: allergic reactions and anaphylaxis such as itching, urticaria, rash, angioedema, abdominal pain, respiratory failure, tachycardia, chest drum and shock have been reported in single cases.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Vitamin B1 is contraindicated in the following cases: Hypersensitivity to thiamin or any ingredients of the drug.

Precautions when using

No report.

The ability to drive and operate machinery

There is no research on the ability to drive and use machinery. However, patients should be warned before driving or operating machinery.

Pregnancy

There is no clinical data on high -dose vitamin B1 for pregnant women so they do not use this drug for pregnant women.

Breastfeeding period

There is no clinical data on high doses of vitamin B1 for nursing women, so do not use this medication for nursing women.

Medicinal interaction

Thiamin can increase the effects of neurotransmitter.

antagonists with thiamin such as Thiosemicarbazon and 5-Fluorouracil may cause loss of thiamin effect. Concomitance these drugs may have to adjust the dose of thiamin.

Thiamin may give a false positive result when planning urobilinogen according to Ehrlich reaction. High doses of Thiamin may affect the keratimal of theophyllin concentration in the spectrum.

Storage

Avoid heat and direct light. Store at room temperature, cool and dry place.

Other drugs

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