Vitamin C 500mg Vidipha supports the treatment of Thalassemia (10 blisters x 10 tablets)

Dosage form Hard capsules
Specifications Box of 10 blisters x 10 tablets
Ingredient Vitamin C
Indication Scorbut disease
Contraindication Kidney stones, urinary stones, anemia due to glazed G6PD, Thalassemia

Ingredient

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Composition information	Content
Vitamin C	500mg

Uses

Indication

Vitamin C 500mg Vidipha is indicated in the following cases:

Treatment of vitamin C deficiency. Vitamin C is involved in the metabolism of phenylalanin, tyrosin, folic acid, norepinephrin, histamine, iron and some drug metabolic enzymes, in using carbohydrates, in lipid and protein synthesis, in immune function, in resistance to bacterial infections, in preserving the integrity of blood vessels and in cell respiration.

Deficiency of vitamin C leads to Scorbut disease, including the combined mistagon with the symptoms of healing wounds, defects in teeth structure, capillary rupture causes many spots of bleeding, blood bruises, bleeding under the skin and mucosa (usually bleeding). Using vitamin C completely loses the symptoms of vitamin C deficiency.

pharmacokinetics

absorption:

Vitamin C is easily absorbed after drinking; However, absorption is a positive process and may be limited after huge doses. In normal human research, only 50% of a dose of 1.5g of vitamin C is absorbed. Absorption of vitamin C in the stomach - intestines can be reduced in people with diarrhea or gastric disease.

Normal vitamin C levels in plasma are about 10 - 20 micrograms/ml. The entire Viatmin C in the body is estimated at about 1.5g with about 30 - 45mg of daily rotation. Clinical signs of Scorbut disease often become clear after 3-5 months of vitamin C deficiency.

Distribution:

Vitamin C is widely distributed in body tissues. About 25% of vitamin C in plasma combined with protein. Vitamin C is secreted into breast milk.

Era:

Vitamin C oxygen - chemical reversible into dehydroorscorbic acid. A little vitamin C converted into non -activity compounds including ascorbic acid - 2 - sulfate and oxalic acid excreted in urine. The amount of vitamin C exceeding the needs of the body is also quickly excreted into urine in the form of unchanged. This usually happens when the amount of vitamin C is imported daily exceeds 200mg.

Before taking Vitamin C 500mg Vidipha supports the treatment of Thalassemia (10 blisters x 10 tablets)

How to use

Take oral use.

Dosage

Vitamin C (Scorbut):

Adults: 1 tablet/day, drink for at least 2 weeks.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Symptoms:

Symptoms of overdose include kidney stones, nausea, gastritis and diarrhea.

Treatment:

Diuretic by infusion may work after a large dose.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using vitamin C 500mg, you may experience unwanted effects (ADR):

Increase oxalate - urinary, nausea, vomiting, heartburn, abdominal spasms, fatigue, redness, headache, insomnia, and drowsiness occurred.

After taking 1 dose 1g daily or larger, diarrhea may occur.

Instructions on how to handle ADR

Notify the doctor with unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Vitamin C 500mg Vidipha is contraindicated in the following cases:

Contraindicated to use high doses of vitamin C for people with glucose deficiency - 6 - phosphate dehydrogenase (G6PD) (risk of hemolytic anemia) people with a history of kidney stones, oxalate oxalate and oxalate metabolism (increased risk of kidney stones), thalassemia disease (increased risk of iron absorption).

Be cautious when used

Taking high doses of vitamin C can lead to drug -resistant phenomenon, so when reducing the dose, it will lead to vitamin C deficiency

Increased oxalate oxalate may occur after high doses of vitamin C. Vitamin C can cause urine acidification, sometimes leading to urate or cystin precipitate, or oxalate stones, or medications in urinary tract.

The ability to drive and operate machinery

should be cautious when driving or operating machinery due to drugs can cause unwanted effects.

Pregnancy

Vitamin C passes through the placenta. There are no studies both on animals and pregnant women, and if vitamin C is used according to normal needs, there is no problem on people. However, taking large amounts of vitamin C during pregnancy can increase the need for vitamin C and lead to scorbut disease in babies. Therefore, do not use more than 1g/day for pregnant women.

breastfeeding period

vitamin C distributed in breast milk. Breastfeeding people use vitamin C according to normal needs, there is no problem that occurs for babies.

Interactive drug

Vitamin C interacts with oral contraceptives, anti -acid drugs containing aluminum.

Simultaneously used in the ratio of over 200mg of vitamin C and 30 mg of elemental iron to increase the absorption of iron through the stomach - intestines; However, most patients have the ability to absorb iron to drink fully without having to use Vitamin C simultaneously.

Simultaneous use of vitamin C with aspirin increases the secretion of vitamin C and reduces aspirin secretion in urine.

Simultaneous use of vitamin C and fluuphenazin leads to a decrease in plasma fluphenazin levels. Acid - chemical urine after taking vitamin C changes the excretion of other drugs.

Vitamin C high doses can destroy vitamin B12; It is necessary to advise patients to avoid high doses of vitamin C within an hour before or after taking vitamin B12.

Because vitamin C is a powerful reducing agent, it affects many tests based on oxygen -reducing reactions. The presence of vitamin C in urine increases the amount of glucose if quantitative with copper reagent (II) sulfate and false reduction of glucose amount if quantitative by glucose oxydase method. With other tests, it is necessary to consult a specialized document on the effects of vitamin C.

Storage

In a dry place, the temperature does not exceed 30 ° C, avoiding moisture and light.

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