Voltaren 100mg Novartis treatment for inflammation and degeneration of rheumatism (1 blister x 5 tablets)

Dosage form Box of 1 blister x 5 tablets
Specifications Diclofenac sodium

Ingredient

Composition information	Content
Diclofenac sodium	100mg

Uses

indications

The drug sets of voltaren 100mg is indicated in the following cases:

Inflammatory and degenerative forms of rheumatism: rheumatoid arthritis. Adolescence rheumatoid arthritis, Age -adhesive spinal inflammation , osteoarthritis and vertebral arthritis, spinal pain syndrome, fibroiditis (low disease in joints).

The acute attacks of gout.

Pain, inflammation and swelling after trauma and after surgery, as follows tooth surgery or orthopedic.

Pain diseases and/or inflammation in gynecological, such as Phat Phat Sutta or Annamiditis.

Migraine .

is a supplementary treatment for inflammation with severe pain in the ear, nose or throat, such as

tonsillectomy, otitis. It is necessary to keep the general treatment principle, which disease requires that treatment regimen and adding Voltaren. If the fever should not be used. Diclofenac works by strong inhibiting the ability to biosynthesis prostaglandin, prostacyclin and thromboxan are intermediate inflammatory and painful substances.

Pharmacokinetics

absorption

Diclofenac absorbs quickly when placing bullets, although the absorption speed is slower than taking the tablet dissolved in the intestine. After using a 50 mg bullet pills, the peak concentration of plasma is achieved within 1 hour, the maximum concentration when using the same unit of dose is about two -thirds of the concentration achieved when using a tablet in the intestine.

Distribution

99.7% diclofenac binds to plasma proteins, mainly with albumin (99.4%).

Metabolism

Partially metabolic drugs takes place by molecular glucuronyl, but mainly in the way hydroxyl hod and methoxyl flower once or multiple times.

Elimination

About 60% of the dose is eliminated in urine in the form of a complex. The remaining drug is eliminated in the form of metabolites through the bile and then followed.

Before taking Voltaren 100mg Novartis treatment for inflammation and degeneration of rheumatism (1 blister x 5 tablets)

How to use

Bullets are taken deep into the rectum. Should use bullets after defecation.

Do not drink, only rectal sugar.

Dosage

Adults

The daily starting dose is recommended by 100 to 150 mg. In case of mild disease or long -term use, 75 - 100 mg is sufficient every day. The total dose is divided into 2 to 3 times a day. To relieve pain at night and numb in the morning, need to be treated with tablets during the day, supplementing the use of bullets at bedtime (to the maximum daily daily dose of 150 mg).

Dysmenorrhea: daily dose depending on each person, usually 50 - 150 mg.

Treatment of migraine pain with Voltaren tablets, should start taking a dose of 50 mg when there is the first sign of the upcoming pain. Use additional tablets until the dose of 100 mg at the same day, if necessary. Patients need to continue treatment on the following days. The maximum dose per day should limit up to 150 mg and must be divided many times.

Children

Voltaren 100mg ammunition tablets are not for children and adolescents.

Elderly patients

Use the lowest dose effectively.

SECRETING HEALTH (NYHA I) or important cardiovascular risk factors

Patients with congestive heart failure (classification of NYHA) or have important cardiovascular risk factors should only be treated with Voltaren after careful consideration and only at the dose ≤ 100 mg a day if treated over 4 weeks.

kidney failure

Voltaren is contraindicated in patients with severe renal failure.

Hepatic failure

Voltaren 100mg drug is contraindicated in patients with severe liver failure.

The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

Symptoms

There is no typical clinical disease due to the overdose of Diclofenac. Overdose can cause symptoms such as vomiting, gastrointestinal bleeding, diarrhea, dizziness, tinnitus or convulsions. If the poisoning is severe, there is an acute renal failure and liver damage.

How to handle

Processing acute poisoning is mainly by symptomatic support and treatment.

It is necessary to take measures to support and treat symptoms of complications such as hypotension, kidney failure, convulsions, digestive disorders and respiratory inhibitors. Special measures such as the forced or blood transfusions may not help eliminate NSAIDs, including Diclofenac because the drug is highly linked to plasma proteins and rapid metabolism.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using Voltaren 100mg , you may experience unwanted effects (ADR).

Common, ADR> 1/100

Neurology: headache, dizziness, dizziness.

Gastrointestinal disorders : Nausea, vomiting, diarrhea, indigestion, abdominal pain, flatulence, anorexia.

Liver: Increase transaminase.

Skin and subcutaneous tissue: Ban skin.

Common disorders and places of drug use: irritating to the drug.

Uncommon, 1/1000

Heart disorders: myocardial infarction , heart failure, chest drum, chest pain.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Voltaren pills 100mg contraindicated in the following cases:

People who are sensitive to active ingredients or catch any excipients.

There is an ulcer, bleeding or perforation of the stomach or intestines.

The last three months of pregnancy.

Hepatic, kidney or heart failure.

Patients with acetylsalicylic acid urticaritis, urticaria or acetylitis or other NSAIDs.

Rectal inflammation.

Be cautious when using

Unused use with other NSAIDs in the line using the whole body, including COX - 2 inhibitors, due to the increase of unwanted effects.

Be careful when used for the elderly. In particular, the lowest dose must be effective for elderly patients and lightweight people.

Be cautious in patients with asthma, seasonal allergic rhinitis, swelling of the nasal mucosa (nasal polip), COPD or chronic respiratory infections (especially if there are symptoms like allergic rhinitis), reactions with NSAIDs such as asthma attacks, quincke edema or urticaria.

Need to closely monitor and pay special attention when prescribing patients with symptoms of gastrointestinal disorders or a history of ulcer, bleeding or perforation of the stomach or intestines due to drugs that increase the risk of gastrointestinal bleeding.

Patients with a history of digestive detox, especially the elderly, should tell the doctor about any abdominal abdominal symptoms (especially gastrointestinal bleeding).

Need to closely and carefully monitor patients with ulcerative colitis or Crohn disease, because the disease can become dramatic.

Be cautious when used for patients with heart or kidney function damage, hypertension, elderly, patients are treated simultaneously with diuretic or drugs that affect kidney function, and patients with non -sacrifices of subtle epidemics due to catching any causes.

Hepatitis can occur when used dielofenac without warning symptoms. Precautions should be used when using Voltaren for patients with dysplasmic porphyrin metabolism. Because the drug can cause acute porphyrin attacks.

Voltaren can temporarily inhibit platelet's convergence. Patients with hemostatic disability, need to monitor carefully.

The ability to drive and operate machinery

Patients taking drugs that have visual disorders, dizziness, dizziness. Sleep or central bodies disorders while using Voltaren should not drive or operate machinery.

Pregnancy

should not use Voltaren for the first 6 months of pregnancy, unless it is more beneficial to the mother than the risk of pregnancy. Do not use diclofenac for the last 3 months of pregnancy due to the possibility of uterine and/or arterioscleros.

breastfeeding period

diclofenac into breast milk in small quantities. Therefore, do not use Voltaren while breastfeeding to avoid complications for babies.

Drug interaction

diclofenac used with lithium may increase lithium concentration.

Digoxin: When used simultaneously, diclofenac can increase the concentration of digoxin in plasma. Need to monitor Digoxin content in serum.

Diuretics and hypertension drugs: simultaneous use of diclofenac with diuretics and hypertension treatment (beta blockers, angiotensin enamel inhibitors can reduce the effect of lowering blood pressure.

Other NSAIDS drugs and corticosteroids: increase the frequency of unwanted effects of the digestive tract.

Anticoagulant and anti -plateletic drugs: simultaneously using the risk of bleeding.

Serotonin recovery inhibitors (SSRIs): Tim their body -use drugs, including diclofenac and SSRIs may increase the risk of gastrointestinal bleeding.

Diabetes treatment: Need to change the dose of anti -diabetes when used in combination with diclofenac.

Methotrexate: Be cautious when taking the drug before or after using methotrexat less than 24 hours, due to increasing toxicity of methotrexate.

ciclosporin: diclofenac increases the kidney poisoning of ciclosporin.

Quinolon antibiotic: can cause seizures.

CYP 2C9 inhibitors are effective: recommendations to be careful when prescribing simultaneously diclofenac with CYP2C9 inhibitors effective (sulnpyrazone and voriconazole).

Phenytoin: When used simultaneously with diclofenac, the control of phenytoin concentration in plasma is recommended by the prediction of increased exposure to phenytoin.

Storage

Do not store over 30 ° C.

Keep the drug in the original packaging.

The pill is not used after the "exp" on the packaging.

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