Vorifend Forte 500mg Stella medicine reduces symptoms of knee osteoarthritis (6 blisters x 10 tablets)

Dosage form Box of 6 blisters x 10 tablets
Specifications Glucosamine

Ingredient

Composition informationContent
Glucosamine500mg

Uses

indications

Vorifend Forte is indicated in the case of:

Symptoms of mild and medium osteoarthritis .

Pharmacological

glucosamine participates in the synthetic metabolism so the composition of articular cartilage. It is a aminomonosaccharide, the material for synthesizing proteoglycan, when it comes into the body it stimulates cells in the articular cartilage to increase synthesis and coincide, the normal proteoglycan structure. The result of the polymerization process is Muco-polysaccharid, the basic component of the articular cartilage head.

Glucosamine sulfate while inhibiting the enzymes that destroy articular cartilage such as collagenase, phospholinase A, and reducing free radicals to destroy cartilage cells. Glucosamine also stimulates bone tissue reproduction, reduces the loss of calcium of bone.

Because glucosamine increases the production of joint mucus, increases viscosity, increases the lubrication capacity of joint fluid. Therefore, Glucosamine not only reduces the symptoms of degenerative joints (pain, difficulty moving) but also prevents osteoarthritis and prevents progression.

It is the mechanism of action on the pathogenesis of osteoarthritis, treating osteoarthritis diseases both acute and chronic, painful or painless, improving joint function and preventing progression, restoring cartilage structure.

Dynamic pharmacokinetics

glucosamine sulfate absorb 90 - 98% through the gastrointestinal wall, easily transported into articular cartilage cells, to stimulate the synthesis of glycosaminoglycan (the main factor creating cartilage).

Birth of glucosamine is about 26% after the first metabolism through the liver. Animal studies have shown that glucosamine quickly diffuses into tissue and combined with serum protein and other biological structures of the body, liver, kidneys, articular cartilage, places where the highest glucosamine concentration is concentrated.

In addition to the transforming path through the liver, glucosamine can be converted into CO2, and excreted by respiratory tract.

A part of non -metabolized glucosamine in the liver or not combined with plasma proteins is excreted mainly through urine; Glucosamine is found in feces as an absorption part.

According to animal radioactive studies shows the sale time of the drug is about 28 hours.

Before taking Vorifend Forte 500mg Stella medicine reduces symptoms of knee osteoarthritis (6 blisters x 10 tablets)

How to use

Vorifend Forte is used by oral.

Dosage

Adults over 18 years old: Drinking from 1250 mg to 1500 mg of glucosamine/day (equivalent to about 1592 - 1910 mg of glucosamine sulfate), divided 3 times. Can use Glucosamine Sulfate alone or in combination with other drugs such as chondroitin 1200 mg/day.

Time to use the drug depending on the individual, at least use continuously for 2-3 months to ensure the effectiveness of treatment.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when using overdose?

No report.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Vorifend Forte, you may experience unwanted effects (ADR).

Common, ADR> 1/100

No report.

Uncommon, 1/1000

No report.

Rare, ADR

Overall very light, transient.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Vorifend Forte is contraindicated in the following cases:

  • Pregnant women;
  • Lactating women;
  • Silibrium children under 18 years old because there is no data on safety and effectiveness.

    • Be cautious when using

    glucosamine does not cause gastrointestinal disorders, so it can be treated for a long time. Treatment should repeat 6 months or shorter depending on the condition.

    The effect of the drug can start after 1 week, so if the pain is more pain, anti -inflammatory analgesic can be used in the first days.

    The ability to drive and operate machinery

    There has been no research on the effects on the ability to drive and operate machinery.

    Pregnancy

    No drugs.

    breastfeeding period

    No drugs.

    Drug interaction

    when used with heparin is likely to increase the risk of bleeding.

    Cavalry of the drug: Because there is no study of the correlation of the drug, not mixing this drug with other drugs.

    Storage

    Store in closed packaging, dry place. The temperature does not exceed 30 ° C.

    Other drugs

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