Zantagel Supp JS Pharm mixture treat acute and chronic pain, gastritis (20 packs x 10ml)

Dosage form Box of 20 packs x 10ml
Specifications Oxethazaine, aluminum hydroxyd, magnesium hydroxide

Ingredient

Composition information	Content
Oxethazaine	20mg
Aluminum hydroxyd	582mg
Magnesium hydroxide	196mg

Uses

Indications

Zantagel drugs are indicated in the following cases: Acute and chronic pain, gastritis, duodenum ulcer, esophagitis and indigestible abdominal pain during radiation therapy.

Pharmacokological

Oxethazain: Testing shows that Oxethazain has the effect of reducing spasms on smooth muscles. The effect of reducing spasm of oxethazain is because it is antagonistic to the effect of serotonin on plain muscle.

Dry aluminum gel: Hydroxyd aluminum has the ability to increase gastric pH. The increase in gastric pH caused by antacids will inhibit the protid elimination effect of pepsin, this effect is very important in patients with stomach ulcers. Aluminum hydroxyd is often used in combination with antacids containing magnesi to reduce constipation.

Magnesi Hydroxyd: Antacid contains magnesi are inorganic magnesium compounds in acids that release anions that neutralize gastric acid, or cushion for gastric juice, but does not affect the production of gastric juice. As a result, the stomach pH increases, reducing acid increasing symptoms. The drug also reduces the acidity in the esophagus and reduces the effects of pepsin enzymes. Magnesi Antacid also has a laxative effect, so it is often used in combination with aluminum Antacid to reduce the constipation effect of Antacid aluminum.

pharmacokinetics

Oxethazain: Oxethazain is biological metabolism very quickly and strongly, so the semi -waste time in the serum of the drug is short. Under 0.1% of oxathazain is detected in urine in the form of unchanged within 24 hours. The main metabolites of oxethazain are beta - hydroxy - mephantermin and beta - hydroxy - phentedmin.

Dry aluminum gel Hydroxyd: aluminum hydroxyd slowly dissolves in the stomach and reacts with stomach hydrochloric acid to form aluminum chloride and water. In the small intestine, aluminum chloride quickly transformed into insoluble aluminum salt, less absorbent. Aluminum is found in antacids (except for aluminum phosphate) in combination with food phosphate into the formation of non -soluble phosphate aluminum and excreted in feces.

Magnesi hydroxyd: Magnesi hydroxyd reacts with hydrochloric acid to form magnesi chloride and water. About 15 - 30% of the Magnesi Chloride has just produced and then eliminated through urine in humans with normal kidney function. The remaining amount of Magnesi Hydroxyd has not been reacted to form Magnesi Chloride can be metabolized in the small intestine and is negligible.

Before taking Zantagel Supp JS Pharm mixture treat acute and chronic pain, gastritis (20 packs x 10ml)

How to use

take 15 minutes before eating or before going to bed.

Dosage

Adults

Take 1/2 pack - 1 pack, 3-4 times.

Children

There is no encouragement for children.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? Treatment of support and support for symptoms.

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Zantagel Supp JS, you may experience unwanted effects (ADR).

Unknown frequency:

Digestive: diarrhea, constipation.

Hypersensitivity reactions: skin rash, tongue inflammation.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Zantagel drugs are contraindicated in the following cases:

Hypersensitivity to the ingredients of the drug.

Using Tetracyclin antibiotics.

Patients with symptoms of appendicitis, because the drug increases the danger level of leakage or hernia because of the side effects causing constipation or diarrhea of aluminum hydroxyd and magnesium hydroxyd.

Patients with blood phosphate decreased because aluminum salt increased to keep phosphate.

Patients with severe renal impairment due to drugs that increase the risk of increased magnesium.

Children under 6 years old because of the risk of aluminum poisoning or the risk of increased blood magnesium, especially in children dehydration or kidney failure.

Pregnant and lactating women.

Precautions when using

Caution should be careful with people with congestion, edema, cirrhosis, low sodium diet and for new people with gastrointestinal bleeding.

The ability to drive and operate machinery

Because the drug has an unwanted effect that causes dizziness and drowsiness, should be cautious when driving and operating machinery.

Pregnancy

must not be used for pregnant women because of the safety of drugs in pregnant women who have not been studied.

Breastfeeding period

Not used for breastfeeding women because of the safety of nursing women who have not been studied.

Drug interaction

If the urine is alkaline after taking antacids, it can lead to the risk of increasing the concentration of quinidine in the blood and leading to poisoning.

Use zantagel with tetracyclin drugs, iron salts, isoniazid, and ethambutol that can reduce the absorption rate of the drug.

Storage

Store in closed packaging, avoid light, at temperatures below 30 degrees C.

Other drugs

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