Zidocin DHG medicine for acute oral infections (2 blisters x 10 tablets)

Dosage form Box of 2 blisters x 10 tablets
Specifications Spiramycin, metronidazole

Ingredient

Composition information	Content
Spiramycin	750000iu
Metronidazole	125mg

Uses

Indications

Zidocin DHG 2X10 is indicated in the following cases:

Treatment of acute, chronic oral dental infections, especially tooth abscess, gingivitis, stomatitis, periodontitis, ear inflammation, jaw inflammation.

Prevention of postoperative oral infections. Spiramycin has antibacterial activity on bacteria that often cause oral diseases such as non -group streptococcal streptococcus, pneumococcal, Mycoplasma, Chlamydia, Corynebacterium, Actitomyces. Metronidazol's antibacterial activity on bacteria often causes oral diseases such as mandatory anaerobic bacilli: Clostridium, Bacteroides fragilis, peptostreptococcus, peptococcus, C. perfringens, Bitidobacterium bifidum.

pharmacokinetic

Spiramycin is not completely absorbed in the digestive tract. Oral drugs are absorbed about 20-50% of the dose of use. The average selling time is 5 - 8 hours. The drug is excreted mainly in bile. Metronidazole often absorbs fast and completely after drinking. The sale time is about 8 hours.

metronidazole metabolizes the liver into hydroxy and acid metabolic substances, excreted in urine partially in the form of glucuronid. Two active ingredients Spiramycin and Metronidazol in Zidocin DHG penetrate well into the tissue tissue, saliva, gums and alveolar bones.

Before taking Zidocin DHG medicine for acute oral infections (2 blisters x 10 tablets)

How to use

Take oral use.

Dosage

Adults

Use 4 - 6 tablets/day, divided into 2-3 times.

In severe cases, 8 capsules may be used.

Children from 10 to 15 years old

Use 3 capsules/day.

Children from 6 - 10 years old

Use 2 tablets/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Overdose and management of Metronidazol: Metronidazole Take a single dose up to 15g has been reported. Symptoms include sadness, vomiting and loss of air conditioning. The nerve effect includes convulsions. Peripheral neuritis has been reported after 5 to 7 days of doses of 6 - 10.4g every 2 days.

Treatment: There is no specific antidote. Symptomatic treatment.

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Zidocin DHG 2X10, you may experience unwanted effects (ADR).

Gastrointestinal disorders: stomach pain, nausea, vomiting, diarrhea.

Allergic reaction: urticaria. Side effects related to Metronidazol such as: Metal taste in the mouth, tongue inflammation, stomatitis, moderate leukemia, dark urine.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Zidocin DHG 2X10 contraindicated in the following cases:

Hypersensitivity to Spiramycin or Metronidazol.

Children under 6 years old.

Be cautious when used

for patients with liver dysfunction, because the drug can be toxic to the liver. Do not drink alcohol during medication. Should check the blood formula for long -term treatment.

The ability to drive and operate machinery

Important when driving and operating machinery.

Pregnancy

should not be used in the first three months of pregnancy.

Breastfeeding period

Should stop breastfeeding while taking the medication.

Medicine interaction

For Spiramycin: Timely use with oral contraceptive drugs that cause loss of conception effect.

For metronidazol: Increasing anticoagulant effect (warfarin) and non -reducing muscle relaxants (vecuronium). Used with alcohol causing Disulfiram -style reaction. Increases lithium concentration in serum. Phenobarbital increases metronidazol metabolism.

Storage

In a dry place, the temperature does not exceed 300C. Avoid light.

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