Also

Also's disease overview

congenital heart disease are not rare cardiovascular diseases but relatively complicated and still have many burdens and challenges for medicine. One of the most common congenital heart diseases and relatively simple is and arterioscleros . So, what is still disease ?

Aortic artery is a congenital structure that connects the pulmonary arteries and the aorta. The connection position is 5-10mm from the starting point.  During the fetus, the lungs are not active, the lung resistance is high, the blood from the right ventricular into the pulmonary circulatory system is small, mainly through the artery into the aorta. The ductus arterioscleria will play the function for about 10-15 hours after birth and close the surgery at 2-3 weeks old. There are many factors that affect the closing of arterioscleros. If the arteriosus is not closed during this period, it will cause disability and arterioscleros.

Causes of Also's disease

  • After the oxygen saturation during the circulation of the system increases, the most powerful factor stimulates the smooth muscles of the arterioscleros, causing the tube close. Children who are born with a long -term muscle response to the ductus arteriosus with oxygen are inferior to children. Thus, children born in months are easy to be at risk of arteriosclerotic. In addition, children with neonatal respiratory failure also make it difficult to close.
  • Another factor that also affects the arteriosclerary is Prostaglandin E2 (PGE2). After giving birth, prostaglandin E2 decreases in the blood (because the child is separated from the fetus vegetables - the source is high in PGE2 and increases the blood flow to the lungs, increasing the excretion of PGE2 through the lungs). PGE2 decreases to make shrinking and closed arterioscleros. Many lung diseases in newborns reduce the excretion of PGE2, increasing the risk of arteriosclerotic.

    Symptoms of Also's disease

  • At each age, the symptoms of the ductus arterios are different
  • From 3-6 weeks, children can show rapid breathing, sweating, difficulty eating, eating poorly, weight loss
  • Children often have dry cough, lower respiratory tract infections, pneumonia
  • If the arterioscleros, the child may not show symptoms until the time is large, only the love is discovered when there is a blow in the heart area
  • Adults still have arteriosclerotic, often go to the doctor because of the symptoms of heart failure (shortness of breath during exertion, having shortness of breath at night ..), arrhythmia. P>

    Purple symptoms (appearing in the lower limb) when Shunt has reversed, the blood flow is no longer from the aorta to the pulmonary artery through the artery but the vice versa from the cave pulmonary artery.

    People at risk for Also's disease

  • Premature babies born
  • Women: The proportion of women with illness is 2 times higher than men.
  • Family history of people with congenital heart disease
  • Babies born with genetic diseases: Down syndrome, Noonan syndrome, CRI-DU-CHAT syndrome ... have a higher rate of ductus arteries
  • The mother is infected with rubella during pregnancy
  • Birth in the highlands: Babies born in the highlands are at higher risk of arteriosus
  • Prevention of Also's disease

    There is no measure that can be sure to prevent the disease, but a healthy pregnancy can partly limit the risk of disease:

  • Supplement with vitamins, especially folic acid
  • Full vaccination before pregnancy 3 months
  • Avoid contact with sources of infectious diseases
  • Exercise regularly
  • Hypoglycemic control: gestational diabetes can cause many effects on the fetus
  • Diagnostic measures for Also's disease

  • Echocardiography: is a simple, easy -to -do and high precision measure. On ultrasound can determine the size of the tube, shunt afternoon, measure the function of the heart chamber, the pulmonary artery pressure is estimated to make treatment decisions
  • ECG: It can be seen increasing the left ventricular, right ventricular or both ventricular
  • Chest X-ray: It is impossible to diagnose defined by chest X-ray, but can identify indirect signs such as big heart ball (heart failure), arcs Pulmonary vessels, large atrial atrial on movies
  • Also's disease treatments

  • Medicine treatment: For new -month infant babies, nonsteroidal anti -inflammatory analgesics (NSAID) can be used to close arterioscleria (ibuprofen, indomethacin). NSAID does not work for children full month and adults
  • For children born monthly, children weigh <6kg: If there is no symptoms, can continue to delay intervention until> 6kg. If symptoms of heart failure are not controlled by drugs, surgery may be surgery in specific cases
  • For children> 6kg: When the tube has an indication of intervention, arterial clog intervention with skin appliances is prioritized than surgery
  • For adults: Parents intervention is set when signs of left ventricular overload. The doctor will rely on pulmonary pressure parameters, lung resistance to decide whether or not to intervene. For small, asymptomatic arteries, there is no need to intervene. Contraindicated intervention when there is Eisenmenger syndrome (Shunt has reversed).

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