Amoeba brain abscess

Amoeba brain abscess's disease overview

Abscess caused by amoeba is a common disease in the tropical, subtropical, hot and humid climate, poor socio -economic conditions, backward living habits . This rate is quite high in West African, South Africa, Southeast Asia ... including Vietnam. The disease can occur in all precepts, all ages, but often in the South, mainly in the age of 20 - 40. However, if not treated promptly progress relatively severe, even complications may die.

amoeba -caused brain abscess is due to the amoeba from the intestine to the large circulatory cycle to the brain, causing abscesses in two cerebral hemisphere. Patients with intracranial hypertension syndrome: intense headache, vomiting and nausea, toxic infection syndrome at different levels. The neurological symptoms depend on the location of the brain damage. Abscess due to amoeba in some other organs: Spleen abscess, kidney abscess, female genital abscess ... may be encountered but very rare.

The cause of the disease is caused by the disease of amoeba (Entamoeba Histolytica), common after amoeba dysentery or chronic dysentery.

Cocoons amoeba through food, drinking water ... penetrate the body through the gastrointestinal tract. When reaching the stomach, thanks to the effects of breaking the shell, the four cocoons in the cocoon were developed into 4 small amoeba then they moved down to reside in the ileum, which is rich in nutrients, suitable pH And there are many symbiotic bacteria. Normally, small amoeba does not penetrate into the intestinal wall to cause disease but follow the stool to the colon. Some small amoeba shrinks into cocoons and is also excreted in division is the risk of spreading to others. When the intestinal wall is damaged (due to other bacteria or injuries), the small amoeba attacks into the intestinal wall, reproducing there and produces protein enzymes leading to necrosis of the intestinal mucosa. In the intestinal wall, at first the amoeba causes hemorrhage points in the mucosa, then creates small lumps on the surface of the mucosa and gradually necrosis and forming ulcers. The ulcer can be up to 2-2.5cm wide, around the edge of the gathering, edema and congestion. The bottom of the ulcer is deep to lower the mucosa and covered by pus. The sores close to each other can connect together to form a larger ulcer, deep to the muscle layer and with bacteria that create deep abscesses, which can cause puncture and peritonitis. When the ulcers cause blood vessel damage, the amoeba can penetrate the blood and follow the blood flow throughout the body, causing damage to other organs outside the intestine such as the liver, lungs, brain, etc. into abscesses.

Causes of Amoeba brain abscess's disease

Amip is a protoEaire of the Entamoeba family. In people there are 4 types of amoeba. Only E.Histolytica is also known as E. Activity is disease. The E.Minuta can not cause diseases in the colon and the cocoon that spreads the disease.

After the body is infected with amoeba, the disease causes the characteristic lesions of the colon mucosa, the disease tends to last long and chronic if not treated actively. 

Symptoms of Amoeba brain abscess's disease

Symptoms of brain abscess often grow slowly for a few weeks, but can also appear suddenly as:

  • Change in mental health such as increasing confusion, reducing reflexes and feeling uncomfortable
  • Say less
  • Reduce sensation
  • Reduce movement due to loss of muscle function
  • Change the ability to look
  • Change personality or behavior
  • vomit

    Fever

  • chills
  • stiff neck, especially when fever and chills
  • Sensitive to light
  • For babies, there may be other symptoms such as fontanel, vomiting, crying, spasms at limbs.

    People at risk for Amoeba brain abscess's disease

    Factors that can increase the risk of brain abscess include:

  • Unpaid hygiene.
  • Women may be at higher risk than men. However, the higher rate is not much.

  • The age of infection is about 60 to 70 years old. 
  • Prevention of Amoeba brain abscess's disease

  • Wash your hands before eating, hygiene and drink, avoiding to spread cocoon into food, water
  • Treatment of feces, absolutely do not use fresh vegetable fertilizer. When using fresh vegetables to be washed, disinfected or treated with ultraviolet rays to kill the amoeba cocoon.
  • Treatment of cocoon people with metronidazol.
  • Diagnostic measures for Amoeba brain abscess's disease

    Based on the history and use of amoeba dysentery

    Diagnosis suggested when there are abnormal symptoms of nerves: consciousness, reduction of movement, convulsions, ...

    Diagnostic tests include

  • Regular blood tests: white blood cells increased, blood sedimentation increased.
  • Computerized or magnetic resonance imaging is often more sensitive and more accurate than ultrasound. There are pictures of liver abscess
  • Amoeba detection by Elisa enzyme reaction.
  • Amoeba brain abscess's disease treatments

    amoeba -caused brain abscess is included in medical treatment and surgical treatment. The results of treatment depend on many factors such as the general condition of the patient, the stage of development and diagnosis of the disease, brain damage, early abscess, size, number of positions abscess. Treatment as well as Care of people with brain abscess should be conducted from the beginning to limit complications and sequelae

    Today 3 coordination measures to treat brain abscess due to amoeba are:

  • Special medicine for amoeba
  • Pus removal when it has formed
  • antibiotic combined

    Surgery in combination with amoebaicide use

    Brain abscess surgery is usually indicated in the following cases:

  • Increasing intracranial pressure
  • The abscess does not respond to drugs
  • There is gas in abscess

  • There is a risk of a broken abscess
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