Blood is hard to coagulate

Blood is hard to coagulate's disease overview

Non -freezing blood disease (Hematopopsy), also known as hemophilia, is a rare disorder in which the blood of the patient is not as normal as normal because of Lack of coagulation factors in a series of 12 factors that help coagulation. If the blood is not freezing, the patient may have bleeding for a long time, it is more difficult to stop bleeding after being injured compared to normal people.

Small cuts are often not a big deal, but greater concerns are deep bleeding inside the body, especially in the knees, ankles and elbows. Inner bleeding can damage the organs and tissues of the patient and may be life -threatening.

Hemophilia is a genetic disorder, so the treatment includes regularly adding blood clotting factors to help patients with blood clotting when injured.

So to learn more about what Blood is not freezing , there will be details in the article below.  

Causes of Blood is hard to coagulate's disease

Normally when bleeding, the body will combine blood cells together to form blood clots to help stop bleeding. Blood coagulation is activated by certain factors. Causes of hematoma hemophilia occurs when the patient is missing one of these coagulation factors.

There are several types of hemophilia diseases and most types are inherited. However, about 30 percent of people with difficulty in freezing blood disease without family history of this disorder. In these people, due to spontaneous mutations occur in genes related to hemorrhoids.

Hemophilia disease is a rare situation when the patient's immune system attacks blood clotting factors such as:

  • Pregnancy
  • Autoimmune disease

    • Cancer

    multiple sclerosis (Multiple Screrosis)

    Hemophilia genetics

    Of the most common types of hemophilia disease, the faulty gene is located on X chromosome. Everyone has two sex chromosomes, one from the father and one from the mother. Daughter inherited a X chromosome from her mother and a X chromosome from her father, a son who received a X chromosome from her mother and a Y chromosome from her father. This means that hemophilia disease almost always occurs in boys and is transmitted from mother to child through one of the mother genes.

    Most women with a defect gene are simply a person who carries a disease gene and has no signs or symptoms of difficulty blood. But some people carrying genes may experience bleeding symptoms if their coagulation factors are moderately reduced.

    Symptoms of Blood is hard to coagulate's disease

    Signs and symptoms of hemorrhoids are very different, depending on the degree of lack of coagulation factors. If the level of lack of mild blood clotting is, the patient may only have difficulty clotting after surgery or injury. If serious shortage, patients may have spontaneous bleeding. Signs and symptoms of spontaneous bleeding include:

  • Bleeding of unknown causes and bleeding a lot due to cutting or trauma, or after surgery or dental procedure.
  • Many large or deep bruises
  • Abnormal bleeding after vaccination
  • Pain, swelling

    • blood in urine or stool of patient

  • Nosebleeds without knowing the cause
  • In newborns, babies crying annoying but unable to explain

    • Bleeding in the brain

    A simple bump on the head can cause bleeding into the brain for some people with difficulty blood clotting. This rarely happens, but it is one of the most serious complications that can happen. Signs and symptoms include:

  • Headache, prolonged
  • vomiting many times
    • Sleep or indifferent
  • Look at the couple
  • Suddenly weak or awkward body
  • Convulsions

    • When to see a doctor?

    If the following symptoms, patients should quickly go to the medical facility for timely treatment:

  • Show signs of brain bleeding

    • There is a trauma that causes blood flow constantly

    The joints are swollen when touched and painful when bent

    If there is a history of family disease with difficulty blood, other family members should go to genetic tests to see if they have this disease to have directions timely processing in the future and before getting married.

    Complications of difficulty blood disease may include:

  • Bleeding clear. Bleeding occurs in the deep muscles inside the body, causing the limbs of the patient to swell on the nerve and lead to numbness or pain.
  • joint damage. Inner bleeding can also put pressure on the joints causing severe pain. Do not treat, regular bleeding can cause arthritis or joint destruction.
  • Infection. People with difficulty blood disease are capable of blood transfusion, increasing the risk of receiving polluted blood products. Blood products become safer after the 1980s due to the donated bloodstone for hepatitis and HIV.
  • A disadvantageous reaction to the treatment of coagulation factors. In some people with difficulty blood, the immune system has a negative reaction to the coagulation factors used to treat bleeding. When this happens, the immune system will develop proteins (called inhibitors) inactivating blood clotting factors, making the treatment less effective.

    • Transmission route of Blood is hard to coagulate's diseaseBlood is hard to coagulate

    Difficult blood clots are not infectious, so it is not contagious from patients to healthy people.   

    People at risk for Blood is hard to coagulate's disease

    The biggest risk factor for non -frozen blood is that family members also have this disorder.

    Prevention of Blood is hard to coagulate's disease

    To avoid excessive bleeding and protect the patient's joints:

  • Exercise regularly. Activities such as swimming, cycling and walking can enhance muscles to protect joints. Antagonistic sports such as football, hockey or wrestling ... unsafe for people with difficult blood disease.

    • Avoid some painkillers. The drugs can aggravate bleeding including aspirin and ibuprofen, instead, use acetaminophen (Tylenol, others) to reduce pain safely.

  • Avoid using blood thinners. Prevented drugs that create a blood clot include heparin, warfarin (Coumadin, Jantoven), Clopidogrel (Plavix) and Prasugrel (Effient).
  • Good oral hygiene practice. The goal is to prevent tooth extraction, which can lead to excessive bleeding.

    • Protect children from injuries that can cause bleeding. Wearing a cloth, rubber or knee -protecting leather, elbow pads, helmets and seat belts can help prevent injuries from falling and other accidents. Keep your house without furniture with sharp angles.

    Diagnostic measures for Blood is hard to coagulate's disease

    To Diagnostic hematoma in children and adults, blood tests may show a deficiency of blood clotting factors. Depending on the severity of the deficiency, the symptoms of hemophilia began to have symptoms at different ages.

    Severe cases of hemophilia are usually diagnosed in the first year of life. Mild forms may be unclear until adulthood or some cases know that they have difficulty clotting after bleeding too much during surgery.

    Blood is hard to coagulate's disease treatments

    Due to many different coagulation factors, it produces different types of hemophilia. The treatment method for hematoma includes providing specific coagulation factors that patients lack by intravenous infusion.

    This replacement coagulation factor can be taken from other people's blood or use similar products, called recombinant coagulation factors, not produced from human blood. Other therapies may include:

  • Desmopressin (DDAVP). In difficult blood disease, this hormone can stimulate the body to release many coagulation factors. It can be injected slowly into the vein or in the form of a nasal spray.
  • Anti -fiber oppressive drugs. This drug group helps prevent blood clots from being broken.
  • Fibrin sealants. This group of drugs can be applied directly to wound positions to promote blood clotting and healing. Fibrin fillings are especially useful in dental treatment.
    • Physiotherapy can reduce signs and symptoms if the bleeding in your joints damage your joints. If bleeding in has caused serious damage, patients may need surgery.
  • First aid for chopped cuts. Using pressure and tape will usually take care of bleeding. For small areas bleeding under the skin, using a ice bag.
  • vaccinated. Although blood products are screened, it is still likely to spread the disease through blood transfusion to people with difficulty clotting. If you have hard blood disease , consider the vaccination of hepatitis A and B vaccines.

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