Budd-Chiari syndrome

Budd-Chiari syndrome's disease overview

Budd-Chiari syndrome (English name is Budd-chiari syndrome) is defined as any pathological physiological process that leads to interrupting or reducing normal blood flow. Out of the liver, leading to serious complications.

What is

What is Buddi Chiari syndrome?

After the blood passes through the liver, it flows through the liver veins and enters the lower vena and eventually carrying blood back to the heart. In Budd-Chiari syndrome, this flow is partially blocked, resulting in instant liver veins due to more flow rather than flowing out. The liver becomes swollen and painful when touching. The blockage causes the liquid to leak from the liver into the abdomen, called ascites, this is one of the most common symptoms of Budd-Chiari syndrome. Patients can see the abdomen swells out and feel uncomfortable, shortness of breath and normal eating.

If the congestion spreads and also blocks large blood vessels that bring the blood to the heart from the lower half of the body can cause other places to be edema, common in the ankles, legs and called foreign edema boundary.

There are many options for treating Budd-Chiari syndrome and it is important that the disease needs to be diagnosed early before it causes liver damage or even liver failure.

However, disorders are very rare with its circulation rate that is not known exactly but about 1/100,000 is the most common estimate. Budd-Chiari syndrome occurs in people of all ethnic groups and affects both the same sex.

Budd-Chiari syndrome is named from George Budd, British doctor, who described the first cases in 1845 and Hans Chiari, who is said to have provided the first description of how the syndrome This affects the body in 1899.

Causes of Budd-Chiari syndrome's disease

There are many causes of Budd-Chiari syndrome, mainly due to an increase in the body's body of blood clots. Most patients with Budd-Chiari syndrome have other potential illnesses that cause them to coagulate. However, in many cases, the exact cause of Budd-Chiari syndrome has not been known.

Blood disorders are the most common cause of Budd-Chiari syndrome in the United States. They mainly include bone marrow disorders (abnormal spread of cells from bone marrow) such as polycythemosis (increase the number of red blood cells) and sickle blood cells, blood genetic disorders. Careful monitoring and control of blood condition is the most effective method known to prevent Budd-Chiari syndrome.

In adult women, Budd-Chiari syndrome is also related to the use of birth control pills and pregnancy. In other cases, it may be genetic. Other known causes include:

  • Cancer, especially liver. Liver cancer is the most common cause of Budd-Chiari syndrome in places in the world with high liver cancer incidence.
  • Budd-Chiari due to the lower membrane of the Venous Membranous Obstruction, the most popular in Asia, India and South Africa

    • Infections

  • Liver trauma
  • Use immunosuppressive drugs

    • Vien Vien inflammation

  • Behçet disease

    • Symptoms of Budd-Chiari syndrome's disease

    Clinical manifestations of Budd-Chiari syndrome depend on the level and time of liver veins and venous systems that appear to relieve the liver. Budd-Chiari syndrome may develop rapidly with the following symptoms:

  • Abdominal pain in the upper right of the patient's abdomen
    • ascites
  • liver enlargement due to the accumulation of blood
  • Swelling of legs and ankles
  • Cramps on the legs and feet
  • itching

    • More commonly, Budd-Chiari syndrome can develop in chronic form, when the patient is likely to have long-term ascites and the liver is enlarged. Very rarely, there is a drama, this is the type with sudden and serious onset. In the Buddha-chiara syndrome there are ascites, liver failure and renal failure may occur when the liver failure is fast. Anticipation is present in most patients with drama hypertension.

    In addition, patients may have other symptoms such as:

  • Abdominal

    • Sudden epigastric pain

  • Nausea

    • Vomiting abdominal disturbance + vena system

  • Spleen

    • jaundice

    Varicose -up hemorrhage

    Venous congestion

    Venous thrombosis

  • The tumor of the liver vein
  • cirrhosis
  • legs
  • hemoglobin in urine

    • Intravenous turbocharger

  • Weight increase

    • Hepatitis

    Transmission route of Budd-Chiari syndrome's diseaseBudd-Chiari syndrome

    Budd-Chiari syndrome is not a genetic disease, therefore, it is not possible to spread from patients to healthy people. 

    People at risk for Budd-Chiari syndrome's disease

    Some factors of Budd-chiari syndrome include:

  • Malignant (myeloproliferative neoplasm, or MPN)
  • Blood -causing birth control pills

    • Infections

  • Chronic inflammatory disease

    • Pregnancy

    Poor nutrition is considered a risk factor for Budd-chiari syndrome.

    Prevention of Budd-Chiari syndrome's disease

    Currently, scientists have not found the exact cause of Budd-Chiari syndrome, so there is no specific way to prevent this syndrome. Most importantly, when the patient sees the above symptoms, it is necessary to see a doctor early to detect and treat promptly, avoid severe complications caused by Budd-Chiari syndrome.  

    Diagnostic measures for Budd-Chiari syndrome's disease

    Like many liver diseases, the symptoms of Budd-Chiari syndrome are nonspecific, meaning that they can be symptoms of many other diseases not only the Budd-chiari syndrome. The diagnostic method includes liver function tests (LFT) and imaging tests with ultrasound and computerized tomography (CT)

    Similar ultrasound, technology is used during pregnancy, the direction of the sound waves through the skin through a exploration device when it is transmitted to the liver areas. Anything that snakes will turn back in the form of a reflected sound wave through the probe and will be converted into visible images on the screen. In Budd-Chiari syndrome, a type of scan called Doppler ultrasound, used to get information about blood flow in arteries, veins and help provide enough information to diagnose Budd-Chiari syndrome.

    CT scan can also be used to obtain images, called class cutting, from different angles on the body of the patient by processing computers and displaying cross -sections of tissue and muscles mandarin. This scan may indicate the large size of the liver and the change in liver tissue density due to abnormal blood flow. The liver biopsy may not be necessary if other tests have helped doctors determine the cause of liver problems.

    Budd-Chiari syndrome's disease treatments

    Place the liver venous catheter, in which a tube is taken around the body until it reaches the liver veins. A tool at the top of the ventilation tube in the vein.

    In some cases, anticoagulants like urinase may be specified to break the congestion. This is usually done when sudden coagulation and blood clots have not been given for a long time.

    Most patients with Budd-Chiari syndrome need surgery to unlock their veins. A balloon tube can be used to open congested liver veins. Many patients have surgery to insert a shunt. Shunt acts as a ignorance system, changing the blood circulation route around the clump veins and into a large vein called a venous vein.

    For people with impaired liver function and complications (such as cirrhosis), liver transplant is often the best option.

    Prognosis for people diagnosed with Budd-Chiari syndrome often depends on the blockage and the number of blocked veins. When the veins are still completely clogged, most people if left untreated will die from liver failure for 3 years. When congestion is not completely longer but different. The basic cause of the disease, the diagnosis time, the time of symptoms and the forms of treatment are also extremely important. Long -term survival is possible when the treatment is started before permanent liver damage occurs. Hepatic cells can recover without permanent damage.

    See also:

  • dangerous complications of cirrhosis
  • How to manifest ascites cirrhosis? Li> F4 - severe cirrhosis

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