Capillary leakage

Capillary leakage's disease overview

Syndrome of capillary Systemic Capillary Leak Syndrome), also known as Clarkson disease, is a very rare disorder, characterized by acute recurrence. Calculation and seriousness related to rapid blood pressure decline.

capillary leakage is a condition and proteins leaked from small blood vessels entering the surrounding tissues. This is dangerous because it can lead to low blood pressure, reducing albumin and reducing plasma. Initial symptoms may include nausea, abdominal pain, extreme thirst and sudden increase in body weight, causing fatigue, weak health, even fainting. In the worst case can cause the patient to die.

Capillary leaks differ in frequency, with some people who only appear once in a lifetime, with others may appear many times each year. The batches usually last a few days and need emergency care. The severity is also different and this condition can be fatal.

capillary leaks often occur in adults, rarely encountered in children. This disease rarely recovered completely. The disease decreases may be spontaneous or due to treatment. Ceremony is completely common in children in adults.

Causes of Capillary leakage's disease

System capillary syndrome appears in many different races and countries. Currently, the cause of the disease is still unknown.

  • Capillary leaks are not inherited.

    • A study reported that capillary leakage caused by chemicals of the body damaged or temporarily removal of cells lining into the mucosa of the capillary. . This peeling makes the layers of the capillary wall leak.

    Symptoms of Capillary leakage's disease

    capillary leaks often have warning signs such as nasal congestion, coughing and may be confused with upper respiratory infections. However, patients do not have the characteristic signs of infections such as fever, chills, rash.

    The common symptoms of system capillary syndrome include:

  • Sudden swelling (edema) on the hands, legs and other parts of the body
  • Quick blood pressure loss
  • Shock
  • Dizziness
  • Headache, abdominal pain

    • Weak body tired

  • Nausea

    • Faint

  • The fluid can accumulate around the heart, lungs and soft tissues that cause life -threatening situations

    • Symptoms of chronic capillary leaks:

  • Swelling of the pieces
  • There is an accumulation of fluid around the heart and lungs
  • Increased concentration of hemoglobin and blood hematocrite

    • Reducing blood albumin levels

  • Reducing blood pressure or rarely shock
  • Response well with glucocorticoid, diuretics and aminophylin

    • People at risk for Capillary leakage's disease

    Risk factors leading to capillary leakage include:

  • Elderly

    • Men infection: bacteria, viruses

  • Heart, kidney or liver disease.

    • Prevention of Capillary leakage's disease

  • Immunoglobulin intravenously monthly can help prevent relapse.
  • Prevention with oral medication (Terbutaline, Theophyllline, anti -Leukotriene) may be effective, but may have side effects such as Run Chi.

    • Diagnostic measures for Capillary leakage's disease

    System capillary syndrome is diagnosed based on clinical examination, testing and recurrence of symptoms.

    Clinical: Patients with a combination of hypotension or shock accompanied by blood concentration, and blood albumin.

    Testing:

  • Blood test:

    • Hemoglobin concentrations and hematocrit increases while the number of red blood cells does not increase or increased less.

    Lower blood albumin concentration.

  • Single -line gammopathy search test (an abnormal protein protein is found in the blood).
  • Testing to eliminate infections.

    • Capillary leakage's disease treatments

    Currently there is no cure for system capillary fistula syndrome. Treatment of capillary leaks is mainly supported to stabilize symptoms and prevent serious complications.

    Different treatment principles in two stages of acute.

    The first -stage capillary leak treatment usually lasts a few days, called the recovery stage to control capillary leakage and maintain blood pressure

  • Respiratory stability
    • Intravenous infusion immediately with large volume to prevent blood pressure, can use intravenous and collant albumin.

    Patients should be closely monitored to prevent prolonged low blood pressure will damage important organs such as kidneys. Treatment of the following stage capillary leak

    This is called the reabsorption period (at this time the translation and albumin are reabsorbed into the veins from the tissues). During this period, capillary leakage has decreased and the threat is the risk of epidemic overload

  • Intravenous fluid in combination with albumin and collection may have temporary benefits to increase blood flow to important organs such as kidneys.

    • However, do not use excessive intravenous fluid even though the blood pressure is still low, just maintain the minimum blood pressure to not permanently hurt the organs. Trong.

  • It is necessary to measure intravenous pressure or central artery at the active care unit (ICU: Intensive Care Unit) to monitor and adjust the speed and amount of fluid to be transmitted. P>
  • If excessive intravenous infusion causes enlargement of limbs to be resolved (arm or legs are incised to release the pressure for the amount of fluid in the blood to flow and go away From the expenses) in collaboration with diuretics use.

    • Excessive intravenous infusion can also cause fluid accumulation in the lungs and around other important organs. Many deaths occur during this reabsorption period. glucocorticoids are often used in the acute phase, especially in the reabsorption period to reduce capillary leaks.

    See also:

  • What function does the capillary function? >
  • Genetic bleeding capillary: Causes, symptoms, diagnosis and treatment

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