Crohn

Crohn's disease overview

Crohn's disease is an intestinal inflammation with symptoms of abdominal pain, serious diarrhea, fatigue, weight loss and malnutrition. The inflammation of Crohn's disease often spreads deep into the intestinal tissue layers leading to both pain and weakness, and sometimes can lead to life -threatening complications.

Although there is no complete cure Crohn's disease, care and treatment measures can significantly reduce the signs and symptoms of the disease and even bring long -term remission.

Causes of Crohn's disease

Currently, the exact cause of Crohn's disease has not been known. Previously, it was suspected that the diet and stressful condition leading to the disease, but now the doctors said that these factors worsen the condition but not the cause of Crohn's disease. Some factors such as genetic and immune system problems play a certain role in the development of Crohn's disease.

  • The immune system. The hypothesis is that due to some viruses or bacteria that activate Crohn's disease. When the patient's immune system tries to fight against microorganisms, there is an abnormal immune response, causing the immune system to mistake not only attack microorganisms but also attack cells. In the digestive tract.

    • Genetics. Crohn's disease is common among people with members of the disease, so the gene can play a certain role that makes the next generation more likely to be more susceptible to other families.

    Symptoms of Crohn's disease

    Crohn is a granular chronic inflammatory disease of the digestive tract, but mainly at the end of the small intestine, but it may be seen at all other positions of the digestive pipe. Symptoms of Crohn's disease can be from mild to severe and slowly developing, but sometimes it will appear suddenly, there is no warning. People with the disease may have time when there are no signs or symptoms of the disease, causing them to think that Crohn's condition has been improved.

    When the disease is active, there are typical symptoms as follows:

  • diarrhea

    • Fever tired

  • Abdominal pain and cramps

    • blood in the stool due to Crohn's disease

  • mouth ulcer
  • Reduce appetite and lose weight
  • Pain near or around the anus

    • People with severe Crohn disease will have some other symptoms such as:

  • Dermatitis, eyes and joints
  • Hepatitis or bile duct inflammation
  • Children grow slowly or grow retardation with sexual properties at puberty

    • Meet a doctor if the patient has constant changes in defecation habits or any symptoms of Crohn's disease such as:

  • Abdominal pain

    • blood in stool

  • Continuous diarrhea without responding to non -prescribing drugs
  • Fever of unknown causes lasting from one or two days
  • Unknown weight loss

    • Crohn disease complications may be as follows:

  • intestinal obstruction. Crohn's disease affects the thickness of the intestinal wall. Over time, the parts of the intestine may be scarred and narrowed, leading to blocking the movement of food being digested and absorbed in the digestive tract. As a result, the patient may have surgery to remove the gastrointestinal part of the gastrointestinal pipe.
  • ulcer. Chronic inflammation can lead to ulcers anywhere in the digestive tract, including mouth and anus.
  • Lo fistula. The near or around the anal area is the most common type.
    • anal fissure.
  • Malnutrition. Diarrhea, abdominal pain and cramps can cause poor appetite or intestinal absorption of nutrients for patients leading to common symptoms of iron deficiency or vitamin B-12.
  • Colon cancer. There are Crohn's disease that affects colon, increasing the risk of colon cancer. Experts recommend screening colon cancer for people who do not have Crohn's disease, so colonoscopy every 10 years starts at the age of 50.
    • Anemia, skin care disorders, osteoporosis, arthritis and gallbladder or liver.

    Some drugs to treat Crohn by preventing the functions of the immune system associated with the risk of developing small cancer such as lymphoma and skin cancer.

    Transmission route of Crohn's diseaseCrohn

    Crohn's disease is not transmitted from a sick person to a healthy person.

    People at risk for Crohn's disease

    The factors that increase the risk of Crohn's disease include:

  • Age. Crohn's disease can occur at any age, but the age with the highest disease is about 30 years old.
  • Race. Although Crohn's disease can affect any racial group, it is found that white and eastern European people (Ashkenazi) are at the highest risk. However, at present, the incidence of Crohn's disease is increasing in black people living in North America and the United Kingdom.
  • Family history. Up to 1/5 people have Crohn's disease with family members with this disease.
  • Smoking. Smoking is the most controlled and important risk factor for Crohn's disease. Smoking also makes the disease worse and the risk of patients with surgery higher.

    • Steroid anti -inflammatory drugs.

  • If a person lives in urban or industrial areas, it is likely to have Crohn's disease. This shows that environmental factors, including a high -fat diet or processed food, plays an important role in the risk of Crohn's disease.

    • Prevention of Crohn's disease

    Sometimes patients may feel helpless when faced with Crohn's disease. But changes in diet and lifestyle can help control the symptoms of the disease and prolong the time between outbreaks.

    Diet

    Không có bằng chứng chắc chắn rằng những gì người bệnh đã ăn là nguyên nhân dẫn tới bệnh Crohn. Nhưng một số loại thực phẩm và đồ uống có thể làm nặng thêm các dấu hiệu và triệu chứng của bệnh. If some foods are detected, the symptoms of the disease outbreak, the patient should remove them. Dưới đây là một số gợi ý có thể hiệu quả:

  • Limit dairy products.

    • Try low -fat foods

    Restricting fiber like fruits and fresh vegetables and cereals can make the symptoms of the disease worse. If fruits and raw vegetables make patients uncomfortable, try steaming, grilling or stewing them.

  • Avoid foods like spicy foods, alcohol and caffeine can make your signs and symptoms worse.

    • Other diet measures

  • Eat many small meals.
  • drink lots of liquids. Try to drink plenty of water daily. Water is the best. Alcohol and drinks contain caffeine stimulating the intestines and can make diarrhea worse, while carbonated drinks often create gas causing bloating.
  • Consider using multivitamins. Because Crohn's disease hinders the ability to absorb nutrients and because the diet of the patient can be limited, the supplementation of multivitamins and minerals is often useful and effective. However, it is recommended that patients should consult a doctor before taking any vitamin or supplement.

    • Smoking increases the risk of developing Crohn's disease and once you get sick, smoking can make it worse. People with Crohn smoking are more likely to recur, need to use many drugs and repeat surgery. Smoking can improve the overall health of the gastrointestinal tract as well as bring many other health benefits.

    Although stress does not cause Crohn's disease, it can make your signs and symptoms worse. Although it is not always possible to avoid stress, patients can learn how to manage stress such as:

  • Exercise.
  • Biofeedback.
  • Regularly relax and practice breathing.

    • Diagnostic measures for Crohn's disease

    To diagnose Crohn's disease, the doctor may perform some of the following tests:

  • Blood test to check anemia

    • Hidden blood test in stool.

  • colonoscopy. This test allows the doctor to see the entire colon and the end of the ileum (the end of the ileum) with a thin, flexible tube, with lights and the camera mounted at the tip of the tube. During the endoscopy, the doctor can also take small tissue samples for biopsy. If there are inflammatory cell clusters called granular tumors, help confirm Crohn's diagnosis.
  • Computerized tomography (CT).
  • Magnetic resonance imaging (MRI). The MRI scanner uses magnetic fields and radio waves to create detailed images of agencies and tissues. MRI is especially useful to evaluate the fistula around the anus (MRI of the Pelvic) or the small intestine (MR CLASS).
  • Capsule endoscopy (capsule endoscopy). For this test, the patient swallows a capsule with a camera and the camera will take photos of the small intestine, then transfer the data to the storage machine that the patient is worn on the waist. The images were then downloaded to the computer, displayed on the computer screen and checked the signs of Crohn's disease. The camera escapes from the body after the patient defecates.

    • Crohn's disease treatments

    Currently there is no cure Crohn completely cured and there is no treatment that is suitable for all patients. The goal of treatment is to reduce inflammation that causes symptoms of patients, limit complications, improve long -term symptoms.

  • Anti -inflammatory drugs. These drugs reduce inflammation, but they target the patient's immune system, so they also produce inflammatory substances. For some people, if combining these drugs is more effective than using only a single drug.
  • immunosuppressive drugs.
  • Antibiotics can reduce the amount of drainage and sometimes heal fistula and abscess in people with Crohn's disease. Some researchers also think that antibiotics help reduce harmful intestinal bacteria can play a role in activating the intestinal immune system, leading to inflammation.
  • anti -diarrhea. A fiber supplement supplement helps reduce symptoms of mild to moderate diarrhea by increasing the number of feces.
  • Pain relievers. For mild pain, the doctor may recommend acetaminophen (Tylenol, others) - but not other common painkillers, such as ibuprofen, Naproxen sodium (Aleve).

    • Additional iron. If the patient has chronic intestinal bleeding, it can lead to anemia due to iron deficiency and need to supplement iron.

  • Crohn's disease causes vitamin B-12 deficiency, so patients can be indicated for vitamin B-12, because vitamin B-12 helps prevent anemia, promote growth and growth Normal development and essential for the function of the nerve.
  • Supplementation of calcium and vitamin D.

    • Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

    Popular Keywords