Gallbladder cancer

Gallbladder cancer's disease overview

Gallbladder cancer is a cancer that comes from the cells in the gallbladder.

Gallbladder is a small pear -shaped organ located on the lower right flank, below the liver. It has the function of storing biliary fluid-a type of digestive fluid produced from the liver.

Is the gallbladder cancer dangerous ? Gallbladder cancer is quite rare. However, if detected at an early stage, the ability to cure the disease is very high. But most gallbladder cancer is detected in the late stage, so treatment and prognosis are often very bad.

Gallbladder cancer is a difficult diagnosis because the disease often has no specific symptoms. In addition, the location is covered by the natural liver of the gallbladder to facilitate the development of gallbladder cancer without being detected.

Causes of Gallbladder cancer's disease

Causes of gallbladder cancer are currently unknown. Some risk factors include:

  • gallstones: gallstones are the most common risk factor for gallbladder cancer. Gallstones are also the most common gastrointestinal pathology in the US and 75-90% of gallbladder cancer patients with a history of gallstones. However less than 1% of patients with gallstones progresses into gallbladder cancer. Currently, the cause of some gallstones patients with gallbladder cancer while most other gallstones are not known. 1 cm is recommended to remove because it is highly likely to progress into cancer. Gender: Gallbladder cancer occurs twice in women in men
  • Smoking: Smoking increases the risk of biliary cancer
  • family history : Family history with relatives with gallbladder cancer is a risk factor for the disease
  • Symptoms of Gallbladder cancer's disease

    Signs of common gallbladder cancer include:

  • Abdominal pain: Pain usually starts from the lower right side of the lower right flank
  • Fever

  • Unknown weight loss: 10% of body weight loss without any cause
  • vomiting, nausea: may vomit yellow bile, bitter taste
  • jaundice and yellow eyes
  • Patients can touch the block in the right abdomen
  • In addition, when metastatic gallbladder cancer to other organs in the body will have signs in that organ:

  • Lung metastases: Difficulty breathing, coughing blood, pleural effusion ...
  • Liver: Pain in the right ribs, jaundice, ...
  • bone: bone pain, pathological broken bone
  • brain: headache, consciousness, epilepsy, paralysis ..

    Gallbladder cancer is divided into 4 stages depending on the properties of tumor, lymphadenopathy and metastasis:

  • Stage 1 gallbladder cancer: localized gallbladder tumors, no lymphadenopathy and metastasis.
  • Stage 2 gallbladder cancer: Tumor invasive surrounding tissues, no metastases and metastases far away
  • Stage 3 gallbladder cancer a: Tumor invasive over the walls of the gallbladder but not yet nearby arteries and veins. There is no metastatic and metastatic metastases.
  • Stage 3 gallbladder cancer B: regional lymphadenopathed tumor but not nearby arteries and veins. There is no distant metastasis
  • Cancer of terminal gallbladder: cancer spreads to nearby veins and/or regional lymph nodes but has no distant metastases. Or the metastatic tumor far to other organs

    People at risk for Gallbladder cancer's disease

  • Patients with a history of gallstones, especially gallstones recurrent many times
  • Patients with a history of gallbladder polyps
  • Smokers
  • Alcoholics
  • People with relatives in the family with gallbladder cancer
  • Prevention of Gallbladder cancer's disease

    There is no specific gallbladder cancer. Measures to improve health, healthy eating, regular exercise and regular examination are also proven to have a certain effect:

  • quit smoking
  • Limiting alcohol and stimulants
  • Periodic health check -ups every 6 months
  • Diagnostic measures for Gallbladder cancer's disease

    Biopsy

    is a gold standard for diagnosis of gallbladder cancer. Biopsy samples can be taken according to the following methods:

  • After surgery
  • Endoscopy
  • Gastro -esophagus endoscopy
  • Small needle biopsy under ultrasound or computerized instructions.
  • Endoscopy (ERCP- Endoscopic Retrograde Cholangiopancreatography):

  • Allows directly to see damage
  • Doctors use endoscopic tools through the mouth, esophagus down the stomach and small intestine. The color indicator will be pumped into the bile ducts, then the patient is taken X -ray to observe the existence of the tumor?
  • In case of biliary obstruction can set biliary tract stents during ERCP.
  • The method is often used to detect biliary tumors rather than gallbladder tumors. 
  • However, ERCP helps to assess bile invasive gallbladder cancer.

    Abdominal components

    Assessing the location, size and level of the surrounding invasion of gallbladder cancer

    Abdominal ultrasound

    Simple, easy -to -implement method helps preliminary assessment of gallbladder and bile ducts as well as abdominal organs

    Gallbladder cancer's disease treatments

    Treatment of gallbladder cancer includes the following methods:

    Surgery

  • Gallbladder cutting: Simple gallbladder cutting. It is possible to perform the open gallbladder cutting cholecysters plus the tissue around the gallbladder about 1 inch with the region.
  • Complete gallbladder cutting: gallbladder and liver shaped near the gallbladder, the cholesteroline and the lymph nodes around the pancreas, the artery and veins.

  • Symptom surgery: Decreased biliary obstruction
  • Radiotherapy

  • Supplementary appointments after surgery help destroy the remaining cancer cells.
  • Additional appointments before surgery helps the tumor reduce the size, from unable to surgery to surgery.
  • Chemicals

  • Should be indicated after surgery to prevent recurrent tumors.
  • The American Cancer Association recommends Capecitabine treatment (XELODA) 6 months after surgery
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