Genetic bleeding capillaries

Genetic bleeding capillaries's disease overview

Genetic bleeding capillary is a genetic disease related to blood vessels that cause a lot of bleeding, especially on a large -scale capillary. The disease often causes patients with gastrointestinal bleeding, anemia and may increase the likelihood of stroke.

capillary is a network of blood vessels connecting arteries and veins. When abnormal structure appears in small blood vessels, it is called capillary dilatation. When these abnormalities are found in large blood vessels, they are called venous dynamic defects. When patients suffering from genetic bleeding capillary disease can appear on the two forms.

Causes of Genetic bleeding capillaries's disease

Causes of genetic bleeding capillaries are caused by genetic factors.  These are gene mutations in Endoglin and Activin receptors such as Kinase type 1 on chromosomes No. 9 and 12. The abnormalities on one of these genes will lead to blood vessel rupture and bleeding that cause capillary dilatation. Genetic hemorrhage.

In addition, the factors of endothelial growth also contribute to regulating vascular walls for genetic bleeding capillary disease

Symptoms of Genetic bleeding capillaries's disease

Typical symptoms of genetic bleeding capillary diseases such as:

  • Nosebleeds: nosebleeds repeated many times due to capillary dilatation in the nose. Nosebleeds appear regularly every day or once a month. Usually nosebleeds will occur from 12 years old.
  • Red to purple -colored spots, dark red lace appears on the skin with mucous membranes.
  • Capillary dilatation in other parts of the body, especially the upper half such as: face, mouth, lips, ears, eye conjunctiva, arms, hands, fingers Hands and nails are easy to recognize.
  • Capillary dilatation in the gastrointestinal tract with clinical symptoms such as black stools, blood stools

    • Anemia in patients with genetic bleeding capillary also appears.

  • Venous dynamic defects in the lungs are also seen in patients with genetic bleeding capillary.
  • Venous dynamics in the brain and spinal cord.

    • People at risk for Genetic bleeding capillaries's disease

    Genetic bleeding capillary disease is also often seen in subjects with the disease with the main manifestation of nosebleeds with other pathological conditions.

    Prevention of Genetic bleeding capillaries's disease

  • Currently genetic advice is being applied to prevent genetic bleeding capillary disease. Couples who want to have children and people with a history of genetic family Telangiectasia will be inherited to prevent genetic bleeding capillary relaxation.
    • In addition, other treatments also contribute to prevent stroke and heart failure.

    Diagnostic measures for Genetic bleeding capillaries's disease

    To accurately diagnose genetic bleeding capillary dilatation, it is necessary to rely on clinical examination and subclinical results.

    Clinical diagnosis: appears at least three of the following four signs:

  • Returning nosebleeds many times has no cause.
  • Observe the capillary dilatation in the lips, mouth, fingers, nose.

    • Rooster capillaries, venous dynamic defects in the lungs, spine, gastrointestinal tract and liver

  • Family history of people with genetic bleeding capillaries.

    • Subclinical diagnosis:

  • X -ray: shows the image, size, lung structure of the patient to contribute to finding the location, level of venous dynamic defects in the lungs.

    • Image ultrasound: whether the liver is affected by venous dynamic defects.

    Magnetic resonance imaging: Determining whether the brain of the patient is abnormal in blood vessels or not.

    Echocardiography is called bubble research: This method helps to check blood flow through blood vessels.

    Computerized tomography: Combined with some other techniques to identify abnormalities in the bone and soft tissue of the body.

    colonoscopy, gastrointestinal endoscopy: To detect abnormalities in the digestive tract.

    Genetic bleeding capillaries's disease treatments

    Inherited bleeding capillary disease cannot be completely cured but helps avoid dangerous complications.

    Treatment of genetic bleeding capillary disease is usually based on the positions of the patient's body affected:

  • For the nose: The patient is treated at home by moisturizing the air, using a spray, moisturizing the nose, avoiding strong nose to prevent mild nosebleeds in the disease core. If the nosebleeds are worse, laser and hormone therapy should be used to stop bleeding. Treatment may need skin patching into the partition of the nose.
  • For skin: If the patient appears to change the skin color, can be treated with laser to destroy the tissue on the skin. /p>
  • For stomach and intestines: Treatment includes laser individually, thermal conductivity, hormone therapy or combining these techniques.
  • For the lungs: Treatment with an intravenous hyperactivity measure with pulmonary angiography. The method is carried out by putting thin catheter through a small incision in the groin area, threading into the veins of the malformation, then placing a small ball or coil to prevent blood flow from flowing to this vein.
  • For the brain: Treatment depends on the size and position of the vein dynamic in the brain. Can choose options such as surgery, causing venous hyperactivity, radiation or monitoring and observation.
  • For the liver: this case is very rare, and liver transplant is the selected method.

    • See also:

  • capillary leaks: Causes, symptoms, diagnosis and treatment
  • What function does capillary function?
  • Allergic capillary inflammation

    • Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

    Popular Keywords