Genius necrosis

Genius necrosis's disease overview

Vessel necrosis (English name is Avascular Necrosis) is a bone disease that occurs due to temporary loss or permanent source of blood supply to bone, causing bone tissue cells Starting to die, the bone becomes fragile brittle from the inside. Genorus is also known as bone necrosis, sterile necrosis and ischemic bone necrosis. 

The most common necrotic vein is in the hip joint, femur, arm bone, knee bone, shoulder bone, ankle bone. The disease may affect one or more bones at the same time or may also be many bones at different times. 

Over time, if not diagnosed and treated promptly, the condition will become increasingly worse, causing bone impairment. Finally, the bone weakened to the point where it could collapse, causing pain and disability for the patient. The time leading to severe pain and bone loss of infinite necrosis is from 2-5 years.

Causes of Genius necrosis's disease

Infinite necrosis occurs when the blood supply to the bone is interrupted or impaired, which can be caused by a number of reasons:

  • Injury. When injured, the bone broken or dislocated can also cause damage or destroy the blood vessels in the nearby area. If there is no source of oxygen and stable nutrients, dead bone cells.

    • Narrow blood vessels: The blood flow to the bone may be affected if the bone is supplied by the artery that is narrowed or blocked, the most common is a little small substance Fat - Blood cells are deformed - In the case of patients with sickle cell anemia.

  • Pressure from inside the bone: Some medical treatments or complications of some diseases such as legg-calve-perthes, Gaucher can increase pressure from the inside. Bone, making it harder for blood to penetrate.

    • Symptoms of Genius necrosis's disease

    Genius vascular disease usually does not appear clearly symptoms in the early stages. Only when the disease progresses, most patients show signs of joint pain. First pain only when carrying heavy objects, putting pressure on the bone, then the patient will pain even when resting. The pain may be mild or severe and increased over time.

    When the disease progresses worse and the bone as well as the surface of the joints are broken, the pain will become very serious and can reduce the possibility of movement at the joints affected. The joints are often most affected by infinite necrosis including:

  • Knee: If there is a necrotic circuit in the knee, the pain occurs most often in the inner and upper part of the knee and worse if the patient moves in many areas. .
  • shoulder bone. Some patients have necrotic veins in the shoulder, but the most common is painful by the upper arm necrosis.
  • Hip joints: When the hip necrotic necrosis, the patient may lose its joint function, small bones from the inside, collapse and cause disabilities. P>

    • Hip. In addition to pain in the hip area, the pain can also spread into the groin or go down to the thigh to the knee area.

    Other joints affected by infinite necrosis include:

  • ankle.
  • Foot.
  • Hands.

    • function.

    Spine. wrist.

    Some people suffer from bully infinite necrosis: affected by both hips or both knees. Signs and symptoms may appear suddenly caused by an accident or exercise injury. In other cases, pain and stiffness can be progressive for several months. Some people with necrotic vein may not experience the full millions of symptoms.

    People at risk for Genius necrosis's disease

    Both men and women are subjects that may have infinite necrosis , but the disease is often detected more in men may be due to the way of living of the opposite. This statue. The common age is usually 30 to 50 years old. People can limit the likelihood of disease by minimizing the risk of disease.

    Some of the most common risk factors of infinite necrosis are:

  • Use high doses of corticosteroids (such as prednisone) for a long time: for example, people with chronic diseases such as lupus and rheumatoid arthritis are likely to have necrotic veins. Corticosteroids are expected to increase blood lipids, reducing bone -raising blood causing infinite necrosis.  
  • Use too much alcohol: People who drink alcohol regularly every day for many years will accumulate fat in blood vessels, limiting the flow of blood to bones. The higher the higher the risk of alcoholic drinks, the higher the risk of necrotic vein.
  • Using biphosphonates: Topical users increase prolonged bone density that can cause jaw bone necrosis complications. 

    • The remaining risk factors are easy to cause infinite necrosis including:

  • Injury: Injury or sports injuries or joint breaks can damage the vessels of the surrounding area and reduce blood supply to bones.
  • Consequences of treatment: Cancer treatments such as chemotherapy or radiation can cause bone weakness.
    • organ transplantation: Organ transplantation, especially kidney transplant may increase the risk of necrotic vascular.
  • Dialysis: The process of cleansing blood when kidney failure.

    • Thus, people who are having diseases such as acute pancreatitis, erythema lupus, diabetes, diabetes, sickle cell anemia, Gaucher disease, disease, disease Kienbock. Legg-Calve-Perthes, HIV/AIDS ... are also subjects at high risk of infinite necrosis.

    Prevention of Genius necrosis's disease

    To prevent disease and improve health, people need:

  • Reduce alcohol, absorb alcoholic substances.
  • Maintain low blood cholesterol levels: Tiny cholesterol molecules are common vascular obstruction.
  • Be careful of the use of steroids: Only use steroids as directed by your doctor.

    • Diagnostic measures for Genius necrosis's disease

    To diagnose necrotic vascular disease , the doctor will first conduct clinical examination and ask about the patient's medical history. The doctor will press around the examination of the examiner to find painful places and try the joint rotation in many directions to assess the operation of the joints.

    After that, the doctor may ask the patient to perform a number of tests to determine how many affected bones and the disease has progressed to the stage:

  • X-ray: can only detect changes in bone in the late stage of the disease. In the early stages, X-rays usually give normal results.
  • Magnetic resonance imaging (MRI) and CT: MRI uses radio and strong magnetic waves to create detailed images of internal structures, helping to show changes of bones in the stage earlier than X-rays.
  • Bone radiation (bone projection): A method of small amount of radioactive substance into the patient's veins. When injected into damaged or healed bone tissue, this radioactive material will display into a bright spot on the scan.

    • Many disorders can cause joint pain. The test through images can help determine the diagnosis and offer appropriate treatment.

    Genius necrosis's disease treatments

    The goal of The treatment of infinite necrosis is to prevent continued bone loss. In the early stages of the disease, doctors often offer non -surgical treatments, helping patients reduce pain in a short time. Those methods include:

    Medical treatment

  • Use drugs: anti -inflammatory drugs that contain non -steroids (NSAID) such as aspirin or ibuprofen (Advil, Motrin, others) can be indicated to reduce pain and swelling. For cases of necrotic blood vessels due to blood clotting blocks clogged blood circulation, the doctor may prescribe more blood thinning drugs.
  • Limit the activity of joints: To slow down the lesions, thereby giving bones recovery time, the doctor can ask the patient to use crutches for a few months and drought. Prepare activities affecting joints.

    • Resting, limiting joint movement combined with the use of drugs, this treatment can help you recover and avoid surgery.

  • Physiotherapy exercises: Some gentle exercises can help maintain or improve the range of motion in the joints, helping to improve the operation of the joints. 
  • Electric stimulation: Studies have shown that electric stimulation methods can help promote bone growth. The current can encourage the body to develop new bones to replace areas damaged by infinite necrosis. 

    • When the progression of the disease becomes more complicated, patients often need surgery to be completely cured. There are currently 4 common types of surgery used to treat necrotic vascular disease including:

  • Extract the bones (relieve bone pinch). Perform partial removal of the inner layers of the bone to reduce the pressure in the bone, relieve pain, increase the space that allows the bone to form new blood vessels and stimulate the production of new bones. P>

    • Bone transplant: Take healthy bones from another part of the body and transplant into the area affected by infinite necrosis. Sometimes this is done in combination with extract.

  • Return the bone (open the bone). Alignment, shape bones to reduce pressure on areas affected by necrotic circuit. 

    • Instead. If the bone has necrotic or other treatments is not satisfactory, the patient may need a natural joint replacement surgery to artificial joints. This method requires a few months of recovery, including learning time to use new joints.

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