Goodpasture syndrome

Goodpasture syndrome's disease overview

Goodpasture syndrome , also known as antibodies - resistant to glomerular membrane, is a disease occurring when the body's immune system is confused, producing antibodies against collagen In the lungs and kidneys.

Đây là một bệnh tự miễn hiếm gặp và nếu không được phát hiện và chữa trị kịp thời, bệnh sẽ gây ảnh hưởng nghiêm trọng đêns các cơ quan khác của cơ thể, sau đó sẽ dẫn đến tử vong.

Causes of Goodpasture syndrome's disease

The cause of Goodpasture syndrome has not been found exactly. However, some studies think that genetic may be one of the causes of this disease.

Symptoms of Goodpasture syndrome's disease

Symptoms of Goodpasture syndrome appear slowly, then slowly affect the lungs, and then the kidneys. There are also some cases that progress very quickly and dangerous.

Initial symptoms of Goodpasture syndrome are very vague, including:

  • Fatigue, weakness.
  • nausea, vomiting.
  • Difficulty breathing.
    • Blue skin.

    When affecting the lungs, Goodpasture syndrome has manifestations such as:

  • dry cough.
  • Difficulty breathing.
  • may appear bloody cough.

    • Anemia due to pulmonary hemorrhage for a long time.

    When goodpasture syndrome affects the kidneys, the body of the patient will appear the following symptoms:

  • Not delicious food.
  • The body is tired and uncomfortable.
    • bleeding.

    Little foaming.

    High blood pressure. edema, swelling of the legs, hands, feet.

    urination, urination.

  • back pain in the ribs.

    • Transmission route of Goodpasture syndrome's diseaseGoodpasture syndrome

    Goodpasture syndrome is an non -communicated autoimmune disease.

    People at risk for Goodpasture syndrome's disease

    Targetic subjects with goodpasture syndrome include:

  • Men are at risk of more disease than women.

    • People with adulthood from 20 to 30 years old or people after 60 are at risk of disease.

  • White people are the risk of goodpasture more than other races.

    • Exposure to chemicals such as hydrocarbon solvent, paraquat herbicide.

    Metal dust exposure.

  • Take drugs like cocaine
  • Smoking
  • virus infection, especially influenza virus.

    • Prevention of Goodpasture syndrome's disease

    To prevent Goodpasture syndrome does not occur, the following measures are needed:

  • Maintain a scientific, healthy and hygienic diet.
  • Health exercise, have a daily exercise habit to enhance the body's resistance.
  • No smoking.

    • Limit exposure to toxic chemicals as well as metal dust.

  • When detecting any abnormal symptoms of the body, it is necessary to see a doctor immediately to promptly detect the disease.

    • Diagnostic measures for Goodpasture syndrome's disease

    To diagnose Goodpasture syndrome, in addition to clinical manifestations, patients will be appointed additional subclinical methods to support accurate diagnosis, including:

  • Blood test: For the purpose of finding the appearance of antibodies of lungs and kidneys.

    • Urine analysis test: The appearance of urine protein and red blood cells can lead to suspicion of kidney damage.

  • Chest X -ray: To assess lung damage when there is an image that shows damage, pulmonary hemorrhage.
  • Renal or lung biopsy: To find the characteristics of Goodpasture syndrome.  

    • Goodpasture syndrome's disease treatments

    Principle of treating goodpasture syndrome is:

  • Anti -antibodies are harmful.
  • Control the accumulation of liquids.
  • Control hypertension.
  • Prevent lung and kidney disease.

    • Medical treatment with the following drugs:

  • Oral immunosuppressant inhibitors: Cyclophosphamide, corticosteroids to reduce the production of Goodpasture syndrome antibodies. The immunosuppressive drug used can continue from 6 to 12 months depending on the response of the patient's body.
  • intravenous corticosteroids for use to control bleeding in the lungs.
  • Medications for convergence control and high blood pressure.

    • Treatment of goodpasture syndrome with dialysis procedures:

    The purpose of this measure is to remove harmful antibodies in the blood. Blood is drawn for about 300ml. The plasma is removed by centrifugal machine and replaced later. Continuing, blood after being removed from antibodies will be returned to the body as the original. This measure is usually maintained within 3 to 6 months. Some patients, accounting for about 30%, need for a long dialysis.

    In addition:

  • Renal transplant is also considered for some patients because they cannot recover kidney damage thoroughly.

    • Some cases are indicated for oxygen supplements or breathing and blood transfusion if patients with severe anemia.

  • Change of diets such as reducing salt amounts to control swelling and hypertension.

    • Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

    Popular Keywords