Hong Ban button

Hong Ban button's disease overview

Rose button (English name is Erythema Nodosum) is the inflammation of the subcutaneous fat cells (Panniculitis) manifested in the form of a small, the most common red lump, the most common. In the lower legs. The unknown pathway mechanism, usually occurs in HLA B8 (80%) and 6% of the family nature. This is considered an immune response to different causes (infection, using some drugs) or may be a symptom of some systemic diseases, sometimes it may not be clear. In Vietnam, the most common cause is tuberculosis and streptococcal infection with hemolytic bacteria and treats the cause of the disease completely recovered. The disease is more common in women than men, the rate of 3-7 women/1 male, at any age but is most common in the age of 20 to 40.So what is What is the button.  

Causes of Hong Ban button's disease

The button is confirmed to be a slow reaction to different allergens. The edema, need to be considered for the appearance of antibodies around the blood vessels of the skin. At the first 24 hours, the combination of antibodies and the appearance of neutrophilic white blood cells proves it is like allergic vasculitis. When later than the combination of physical and common antibodies is a monomer's infection. So far, experts do not know the exact cause of the button. It is known that the disease usually occurs in the HLA B8 gene carrying (80%) and 6% of the family nature. The common disease of the Red Rubbon disease in the US and Northern Europe is Lien Tri infection, sarcoidosis and tuberculosis ..

  • Smalled streptococcal infections: a common cause of the disease (especially in England). Because often manifested by acute respiratory infections first, then there is skin damage. But not all cases are due to streptococcus because there are some cases that are not treated with antibiotics.
  • The cause of tuberculosis: Always an important factor in children and young people. 
  • Rose disease appears after 6 weeks of heating. But now in the US and Western Europe, this root is rare and not found in patients under 30 years old, and over 30 years old still has this cause.

    • sarcoidosis: The cause of the disease caused by sarcoidosis and tuberculosis is less and less in Western countries. Nowadays, most authors admit that Hong Ban button is a deformation of Sarcoidosis. This is proved by pathological tissue or Kevin reaction (+).

  • Due to viruses, toxins: In recent years, it is recognized that the role of toxins and viruses causes the Red Red Red Red Red Red Red Red.

    • Other types of infections: such as tuberculosis. Mushrooms: Blastomycosis, Coccidioidomycosis, T. Verrucosum.

  • by drugs: sulphonamides. Especially children with tuberculosis that we treat with sulphonamides are easy to get rash. In addition, there are some antibiotics that often cause this disease.
  • due to intestinal parasites: Redders of buttons due to intestinal parasites are also noticed with the ratio of 14/625, 8/465, 8/415.
  • Organ disease: Malignant blood disease, Hodgkin is also the cause of the disease. But usually only observed when physical therapy.
  • Rose button in leprosum: Red button is often encountered in malignant leprosy. The general manifestation is a state of depression, malaria ... scattered lesions in many places, papules can become atrophy or ulcer with yellow maces. This lesions are usually prolonged due to the immune reaction (detector of type of type arthus).

    • Symptoms of Hong Ban button's disease

    Skin symptoms:

    Clinical images are very diverse: floating into several times, buttons or buttons in the dermis. The skin above the lesions of the edges, pink, red or purple red, painful. The buttons sometimes float along the blood vessel. The special case above the button may form water or necrotic ulcer. In the buttocks, back, sides or lower limbs, there is a purple or purple mesh pattern (Livedo membrane) in hand in hand with dilated capillaries under the skin to form bruises, edema, possibly Accompanied by lumps or mucosal ulcers.

    Neurological and muscle symptoms:

    may have central nerve damage causing epilepsy, paralysis of 2 or 4 limbs, maybe only on one side; coma or peripheral nerve damage; Inflammation of one or more nerves, especially lower limbs, may be accompanied by muscle damage, muscle spasm or muscle paralysis, polymyositis (polymyositis); Corpging into the muscles of the patient feels painful, limiting movement movement, can be accompanied by aches and pains in the joints.

    Symptoms of systemic and internal organs:

    tired, persistent fever, high blood cells, high blood sedimentation speed, eosinophilia increased to 70%. There may be symptoms of blood, vomiting, acute abdominal pain, mesenteric blood vessels or acute pancreatitis, nephritis, cardiovascular collapse, myocarditis. In general, this is a system disease, the skin is only a part of manifestations, disease or recurrence. 

    Transmission route of Hong Ban button's diseaseHong Ban button

    Rose button is a dermatological disease with red or purple skin lesions, which are quite complicated but also from the immune system. The disease is not life -threatening, not contagious but affects the quality of life of the suffering.

    People at risk for Hong Ban button's disease

  • The rate of disease: In England, the rural semi -region has a disease rate of 2.4/10,000 people. At U. K Hospital, this rate accounts for 0.5% of dermatological patients. In Slovenia, 4 years of observation found that the disease accounted for 1% of all patients of the hospital, most of them were due to streptococcus. Races and geography also cause different ratios like Coccidioidomycosis, skin tuberculosis or other infections.
  • Gender frequency: Observing the disease in both sexes but more common in women than men with a score of 6 - 7/1.
  • Age frequency: common disease is from the age of 20 - 30 (coincided with sarcoidosis). But in the US, the disease is common at 40 - 50 years old, while Sarcoidosis is still in the young group.
  • In children, most of them are related to the root of tuberculosis and streptococcus. And for other ages this factor is unknown.

    • Seasonal and social frequency: Most patients see the disease appears in the first 6 months of the year. People have not explained this yet. There is no difference in ratio in industrial and rural production areas.

    Prevention of Hong Ban button's disease

    Currently, scientists have not yet found a method of preventing nodes. Therefore, when patients have symptoms of pink disease, go to a specialized medical facility for early examination and treatment.

    Diagnostic measures for Hong Ban button's disease

    The doctor will examine the external signs of the Red Rong Disease:

  • Red button: Red ban, lumpy, hard papules.
  • The form of a pink button: The lumps can see or touch under the skin, circular; The size can range from 1-10 cm in diameter, usually about 1-2 pieces of this snake, less mobile, around the swollen lumps. Sometimes many corpses combine into a large array.
  • Location: The front of the lower leg, the two sides, the land of the notes can occur anywhere with fat under the skin, including the thigh, arm, body, face , but rare as in the upper limb, on the face and neck.
  • Development: Diverse, different ages with changing colors such as bleeding under the skin (turning into purple, brown, brown, light yellow, and finally blue leaf). The board disappears within 10-15 days, not to get scars or sequelae

    • Symptoms of coordination: Red rash usually appears along with symptoms similar to the flu, fever and feeling of fatigue. Joint pain, epidemic inflammation and stiffness, can occur before or simultaneously with skin damage, and can last up to 6 months

    In addition, the doctor may appoint some subclinical tests

  • Inflammatory syndrome: Increased blood sedimentation rate, multi -neutral leukocytes.

    • Pathological tissue: Skin damage biopsy is only indicated in not typical cases. The results showed that the walls of subcutaneous or chronic panniculitis cells in the fat organization and around the blood vessels.

  • O isolation of beta -soluble streptococcal streptococcus from the throat, ASLO test

    • Test mantoux, lung X -ray (sometimes need to take a ct scan) and detect BK bacteria infection when bronchoscopy.

    Lung X: The lymph nodes on one side are common in infections or malignant diseases; The lungs of the lungs are usually combined with sarcoidosis.

    Not typical: Lesion biopsy

    Distinguish banquet or chronic dermatitis. The first stage to distinguish: erysipelas, insect bites, acute urticaria, shallow vein obstruction, nodulitis. The stage of progression should be distinguished from the node inflammation around the artery; necrotic vasculitis ...

    Hong Ban button's disease treatments

    Treatment of the button usually disappears within 3-6 weeks. It is necessary to treat the cause (tuberculosis, streptococcus) if the cause is detected. Thalidomide is indicated in the case of a button that is used by Mycobacterium leprae (leprosy). Symptomatic treatment includes the following measures.

  • Beds at beds, improving legs, using elastic socks as in the treatment of varicose veins can improve the symptoms of leg edema.

    • Non -steroid anti -inflammatory drugs, painkillers (if necessary)

  • If due to infection: high -dose antibiotics.
  • If due to tuberculosis: Treatment as with skin tuberculosis or internal tuberculosis, no skin treatment.
  • Use corticosteroids in average doses, then gradually decrease and take a long -term strengthening dose.
  • Use na -specific antihistamine.

    • See also:

  • Atopic dermatitis: Things to know
  • Dermatitis - Preventive and treatment methods Li> Children with atopic dermatitis: How to take care of it?

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