Incorrectly anti -hormone secretion syndrome (ADH)

Incorrectly anti -hormone secretion syndrome (ADH)'s disease overview

Incontractive anti -hormone secretion syndrome (ADH) (English name is syndrome of inappropriate antidiuretic hormone - SIADH abbreviation ) is a photo syndrome Enjoy water and minerals balance in the human body, especially sodium. This is the most common cause of hypoglycemia due to the inappropriate adh secretion.

So what is hormone ADH ? Anti -diuretic hormone (ADH) is secreted by a group of hill cells under the brain. They play an important role in balancing blood pressure, blood in the body, the amount of water in the cell by controlling the amount of water as well as the concentration of waste in the urine is excreted outside the body. >

ADH affects the kidneys and blood vessels. The kidneys influenced by ADH will store and penetrate more water, reducing the amount of water excreted from the body, making the concentration of concentration more concentration. And under the influence of ADH, blood vessels will shrink, increase blood pressure, soaked water to the cells more.

ADH syndrome is not appropriate occurs when the amount of AHD in the body is too much. At that time, the patient's body could not eliminate water outside (water retention) and mineral concentration in the patient's blood low.

Causes of Incorrectly anti -hormone secretion syndrome (ADH)'s disease

Due to the pathology in the central nervous system

The hypothalamus of the brain secretes too much ADH.

Stroke.

Alcoholism

Having Guillain-Barre syndrome.

Head injury.

hydrocephalus. infection: meningitis, encephalitis, abscess.

There is tumor in the brain. Due to the drug's use of some drugs that can stimulate the hypothalamus of the brain to release more ADH hormones. Some typical names are: chlorpropamide, clofibone, cyclophosphamide, bromocriptine mesylate (bromocriptin), nicotine, opiat, oxytocin, phenothiazin, vinblastin, vincristin, ... Due to some cancer, some cancers such as cell lymphoma, duodenal cancer, epithelium, nerve tumor, olfactic nerve, thymus tumor, small cell lung cancer, pre -gland cancer paralysis, thymus tumor, ... can stimulate the body to increase ADH secretion, resulting in inappropriate anti -hormone secretion syndrome.

Other causes of HIV, neurological -mental disorders, lung disease, bronchiectasis, chronic obstructive pulmonary disease, pneumonia, excessive water transmission after surgery, tuberculosis, fungus,. .. often suffering from ADH syndrome is not appropriate due to the body's increased secretion of hormones ADH.

Symptoms of Incorrectly anti -hormone secretion syndrome (ADH)'s disease

In the early stages, the inconsistent hormone secretion syndrome is not symptomatic. However, more and more after the disease worsens, the disease will have many symptoms depending on the person. Typically:

Nausea or vomiting.

Cramps or tremors, legs.

Depressed mood, memory impairment, or discomfort.

Change personality, easy to confuse, hallucinations.

seizures, even some cases may be comatose.

If for some reason the amount of sodium in the body of the patient is too low or decreasing rapidly, the symptoms of the disease are even worse.

People at risk for Incorrectly anti -hormone secretion syndrome (ADH)'s disease

The disease is directly related to the amount of water and sodium in the body. Therefore, if either or both of the above factors imbalance, it may increase the risk of anti -hormone secretion syndrome (ADH) inappropriate. Subjects at high risk include:

There is very low sodium concentration in the blood.

In surgery or being treated for brain tumors.

Meningitis.

Sensory disorders, lung cancer or other chronic diseases.

Head injury or brain injury.

Prevention of Incorrectly anti -hormone secretion syndrome (ADH)'s disease

Here are some measures to help prevent and control the condition of anti -hormone secretion of ADH cards inappropriate:

Limit the amount of daily drinking water.

Understand the cause of ADH syndrome is not appropriate to find out the root treatment.

Regularly measuring the amount of sodium in the blood.

Consider other disorders that increase the risk of unsuitable ADH hormone secretion for thorough treatment.

Diagnostic measures for Incorrectly anti -hormone secretion syndrome (ADH)'s disease

Blood and urine tests to evaluate the amount of water and sodium in the body: There is too much water and too little sodium. If the diagnosis of ADH syndrome, the patient will be indicated to treat the causes of sodium drops such as poorly active thyroid (hypothyroidism) or adrenal insufficiency.

Incorrectly anti -hormone secretion syndrome (ADH)'s disease treatments

Inappropriate ADH secretion syndrome is self -limited syndrome, so the best treatment is to adjust according to the pathogenesis. That also means eliminating the cause of increased secretion ADH.

Limit drinking plenty of water when sick to balance the level of sodium in the blood normally. The maximum amount of water that patients are allowed to drink is only a little more than the amount of urine during the day. Patients need to measure the amount of sodium in the blood regularly to ensure the effectiveness of drinking water is effective in treating the disease.

Using antagonists ADH is Demeclocycline. In some emergency situations, the doctor may appoint patients to take strong diuretics like Furosemide to make the patient feel more comfortable.

Prognosis for treatment of anti -urinary hormone syndrome (ADH) is not suitable depending on the main cause of the disease as well as the severity of the blood hypoglyc sodium and millions. The accompanying evidence is different. People with severe hypoglycemia or symptomic hypoglycry hypoglycocytes have a higher mortality rate than mild or asymptomatic, chronic hypoglycemia. The disease will cure if it is completely treated for the main cause of the disease.

See also:

hydrocephalus: Causes, symptoms, diagnosis and treatment

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