Muscle weakness

Muscle weakness's disease overview

What is

myastheniastick?

Myasthenia gravis is a characteristic chronic neuropathy with a muscle weakness that occurs in batches or continuously with different degrees. The muscle group is often affected as muscles, working as desired in the body such as facial muscles, chewing muscles, longan muscles, limb muscles, respiratory muscles, life -threatening due to respiratory failure. P>

Myasthenia gravis is classified as autoimmune diseases, due to the existence of antibodies against acetylcholin receptors on muscle cell membranes in the afterhand of the post -synap nerve. This leads to signals that are transmitted by nerves that are not received by muscle cells. Muscle decline is a chronic, progressive, and worse process to the end of the day. Myasthenia gravis is also recorded related to thymus diseases in 75% of patients, of which the thymus tumor encountered in 15% of cases. Some other autoimmune diseases such as muscle inflammation, ulcerative colitis, rheumatoid arthritis in 10% of the total number of cases.

Disease myastheniastick is not a common disease, but may be seen at any age. Women are twice as affected by men, common in young women under 40 or over 70 years old and men over 50 years old. The average incidence rate is about 0.5/100,000 people.

Clinically, muscle weakness is classified into the following groups:

  • Group 1: Myastheniastick occurs only in longan muscles such as lifting muscles. The symptoms often decrease quickly and remember to respond well to treatment.

    • Group 2a: Myastheniac downs with many muscle groups in the body such as muscles in the limb, body muscles, respiratory muscles but at a mild level.

  • Group 2b: Myastheniac downs with many muscle groups in the body with a moderate level, manifestation of eyelashes, lisp, weak limbs that cannot be moved, swallowed or choked. .  
  • Group 3: My body weakness occurs quickly and suddenly. The body muscles weaken quickly to the most serious level in 6 months. Paralysis of the respiratory muscles appear earlier, in parallel with the muscle weakness in other places such as longan muscles, body muscles, limbs. Patients in this group respond very poorly with medical treatment, so they have bad prognosis with high mortality.
  • Group 4: Myasthenia gravity but chronic progression, slowly, lasting for many years. Patients in this group often have an associated with thymus.

    • Myasthenia gravis progresses through the following basic stages:

  • Stage 1: Only one group of muscles is affected, the first common is longan muscles.
  • Stage 2a: All body groups are affected, except for the respiratory muscle and pharyngeal area.
  • Stage 2b: All body muscles are affected, accompanied by a group of muscles in the pharyngeal area but no respiratory muscles.
  • Stage 3: All muscles are affected, preserving including manifestations of throat and respiratory disorders.

    • Causes of Muscle weakness's disease

    To better understand what my body is, it is necessary to grasp the causes of the disease. Archbishops are characterized by a decrease in trait or loss of continuity in transmitting nerve impulses to the corresponding muscles, causing weak symptoms and clinical paralysis. The hypotheses include:

  • The appearance of antibodies destroys the receptors of acetylcholine on the muscle cell membrane in the posterior membrane. Therefore, the nerve impulses are not received by muscle cells.

    • The existence of antibodies against the enzyme Kinase: This hinders the formation and differentiation of the receptors of acetylcholin.

  • Themius diseases such as thymus tumors, thymus increasing the production of antibodies in the body attack the receptors of acetylcholin.

    • Symptoms of Muscle weakness's disease

    The characteristic symptoms of myasthenia gravis are weak, paralysis of the body, manifest as follows:

  • Weak muscles in the neck of the neck: Mi mi, look, blurred, paralyzed face, difficulty swallowing, hard chewing, extrusion of saliva, changing voice, heads often drooping, facial expressions Often sad, tired.
  • Weak muscles, in myasthenia gravis, the patient does not even lift his hand.

    • Weakness of respiratory muscles: Difficulty breathing, acute respiratory failure.

    Muscle weaknesses often appear at the end of the day, or after a lot of exercise and relieved when the patient rests. The muscles are often affected by one side, asymmetric, and there are different disorders. Neurological reflexes and the feeling of the patient are often not damaged.

    Transmission route of Muscle weakness's diseaseMuscle weakness

    Myasthenia gravis is not transmitted from sick to healthy people.

    People at risk for Muscle weakness's disease

    Young women, people with a history of themselves and their families suffering from thymus diseases or myasthenia gravis are those who are more likely to suffer from the disease.

    Prevention of Muscle weakness's disease

    Myasthenia gravis is now considered an autoimmune disease, depending on the location of each person. Therefore, there is no effective measure to prevent disease.

    Measures to help maintain a good health should be applied, including:

  • Eat nutritious, eat lots of green vegetables and fruits. Papaya and bananas are two fruits that help replenish potassium, need for muscle activity.
  • regular exercise
  • Building a healthy lifestyle
  • See a doctor as soon as there are abnormal manifestations.

    • For those who have been diagnosed with myasthenia gravis memorize the following measures:

  • Potassium supplements, maybe by eating bananas and papaya because of the lack of potassium, making the muscle weakness worse.
  • Prevent infections during the treatment of myasthenia gravis with drugs that impair immunity.
  • Do not arbitrarily stop using the drug, or use other drugs not in the prescription of the doctor.
  • Make a relaxed spirit, avoid anxiety.
  • When there are progressive muscle weaknesses, immediately medical facilities need to be examined and handled.

    • Diagnostic measures for Muscle weakness's disease

    Diagnosis of myasthenia gravis requires a combination of examination of appropriate clinical symptoms and subclinical tests, in which subclinical media play an important role to help accurately diagnose the disease. .

  • Zoly method: Ask the patient to blink 15 consecutive times and open his eyes. Patients who cannot open their eyes are a suggestion for myasthenia gravis.
  • Test Prostigmin: After 15 minutes of prostigmin injection, myasthenia patient can open your eyes normally again. The above result is called a positive test prostigmin.  

    • Mechanical reaction: is a high sensitivity test.

  • Quantifying antibodies of acetylcholin: patients with muscle weakness with acetylcholin antibodies increase. However, if the results within normal limits still do not exclude the disease.
  • chest X -ray, CT scan, breasted breasts to detect abnormal images of the thymus if any.
  • Biopsy

    • Muscle weakness's disease treatments

    Treatment of myasthenia gravis is currently facing many limitations. The disease currently has no complete cure and may recur after a long time.  Myasthenia gravis greatly affects the life and health of the patient. During the progress, the patient may not lift the arm, unable to do anything even the smallest. Cases that late may face shortness of breath, high risk of death. The important thing in the treatment is to detect and promptly handle myasthenia and emergency attacks and respiratory failure of the patient.

    The

    medication in myasthenia gravis, the drugs are indicated to mild symptoms, but do not completely cure the disease. Drugs should be used under the guidance of a doctor.

    Dialysis

    This is a method to directly remove acetylcholin antibodies in the patient's blood. This treatment can be indicated in emergency cases, manifesting acute respiratory failure.

    Surgery

    Surgery to remove the thymus can improve the symptoms of the disease. This method is applied in cases where there are irregular thymus or cases of emergency nature. After surgery, rings are still advised to continue using the drug to treat the disease.

    Living and resting regime

    avoid stress, anxiety

    Eat nutritious nutrients

    Having appropriate rest mode

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