SJOGREN syndrome

SJOGREN syndrome's disease overview

What is

What is sjogren syndrome?

Sjogren syndrome is an autoimmune disease related to the external glands in the body such as rules, salivary glands. The characteristic manifestation of the disease is mucosal dryness, the most common is dry eyes and dry mouth due to lymphocytic contamination in mucous membranes and glands that reduce tears and saliva.

In addition to the reduction and salivary glands, thyroid, joints, skin, lungs, liver, kidneys, and nerve cells may also be affected. With the above abnormalities, the disease greatly affects the quality of life of the patient. This autoimmune disorder often affects women, the incidence of women is 9 times higher than that of men, the most common in middle age from 40 to 60.

Sjogren syndrome often appears with other immune systems, most commonly rheumatoid arthritis, lupus, sclerosis, hepatitis bile stasis, Hashimoto thyroid inflammation, Aortic inflammation and interstitial pulmonary fibrosis. The disease can also appear alone SJOGREN syndrome.

Overall this is a benign disease, often lasting throughout the life of the patient.

Causes of SJOGREN syndrome's disease

Ranked into the autoimmune diseases means Sjogren syndrome is caused by the self -attack of the immune system. The external glands such as rules, salivary glands are impaired by the body's body identified as a strange, harmful ingredient, so it stimulates the attack system to attack. However, the mechanism and exact cause leading to this phenomenon have not been clearly studied. Some authors believe that genetic factors and external environmental agents also increase the likelihood of disease.

Symptoms of SJOGREN syndrome's disease

The tear glands and salivary glands are the two most affected organs in Sjogren's syndrome so dry eyes, dry mouth are the two most common symptoms of clinically clinically facing.

  • dry eyes: The glands of lymphocytes are contaminated with lymphocytes and mitosis should reduce saliva secretion leading to dry corneal inflammation, red eyes, eyelid inflammation. Patients often feel itchy, burning eyes, feeling bustling and increasing light sensitivity. In more severe cases, eye ulcerative complications.
    • dry mouth: Similar to the gland, the contamination of lymphocytes and cytoplasm also occurs for salivary glands. People with Sjogren syndrome reduce saliva secretion should be prone to bad breath, difficult to speak, difficult to chew and swallow, reduce or lose taste. Inflammation of the gums or tooth decay is also more likely to occur.  nose, throat, bronchial rod, skin and vagina may also have to go through the mucosa dryness similar to the eyes and lips.

    Depending on the other pathologies, some other symptoms can also be found in Sjogren syndrome, such as:

  • Fatigue
  • Reduction of vision
  • Painful joint pain
  • Swelling of the gangitis

    • Lymphadenocyt

    Stomach pain

  • Fever, rash
  • Vascular inflammation
  • Pancreatitis
  • Pleural inflammation

    • Renal failure, interstitial nephritis, glomerular damage

    Transmission route of SJOGREN syndrome's diseaseSJOGREN syndrome

    Sjogren syndrome is an autoimmune disease so it is not likely to be infected between humans and humans. Good people are regular, intimate contact or even use common items with people with Sjogren's syndrome that is not likely to be infected.

    People at risk for SJOGREN syndrome's disease

    Everyone is likely to suffer from Sjogren syndrome. However, those who have the following characteristics are more likely to get the disease than others:

  • Women
  • Age 40 and older

    • There is a vapor with other autoimmune diseases such as rheumatoid arthritis, lupus, scleroderma, hepatitis cholestasis, Hashimoto thyroid inflammation, artery and pulmonary fibrosis interstitial ...

  • There are relatives in the family with Sjogren's syndrome, especially parents and siblings.

    • Prevention of SJOGREN syndrome's disease

    Currently, there is no specific preventive measure of the disease due to the unknown cause and risk factors. However, patients can refer to the following ways to limit the progress of Sjogren's syndrome such as:

  • Ensure clean oral hygiene by raising your awareness and regularly coming to the dentist. Drinking plenty of water, stopping smoking are the habits that patients should set.
  • Use artificial tears, eye drops. Glasses when going out to protect the eyes
  • Use skin moisturizer

    • See a doctor as soon as new signs or symptoms of the disease become worse.

    Diagnostic measures for SJOGREN syndrome's disease

    Sjogren syndrome is diagnosed based on the combination of:

    Exploiting the history of yourself and your family, as well as risk factors

    Clinical examination: Typical symptom detection is dry eyes dry eyes , or symptoms of other attached diseases.

    Subclinical test:

  • Blood formula: anemia, leukopenia, eulogy

    • Liver and kidney function

  • SJOGREN antibody detection test
  • ANA antibody antibody test, anti-antibody Anti-60 KD and Anti-La positive
  • Test Schirmer: quantitative tears, assess the condition of the patient's dry eyes.

    • Lip biopsy: Take a sample of salivary glands in the lips as anatomy to detect images of lymphocytic cells.

    SJOGREN syndrome's disease treatments

    Sjogren syndrome treatment currently has a role in improving symptoms for patients but not solving the cause of the disease. So Sjogren's syndrome is still an incurable disease.

    Sjogren syndrome treatment with drugs

    Many drugs are indicated to reduce eye inflammation, dry eyes, increase salivation, joint pain or inhibit immune system.

  • Dried eye treatment: artificial tears, pilocarpin -secreting drugs (pilocarpin) are the two main drug groups selected in light and medium forms. For severe cases when complications appear with corneal ulcers, eyelid inflammation, it is necessary to combine additional antibiotics, obstetric ointments or self -serums.
  • Pilocarpin also has the effect of increasing salivation
  • The immunosuppressive drug group: helps slow down the progression and severity of the disease. Some drugs used are hydroxychloroquine, corticoid, methotrexate.

    • Common painkillers, nonsteroidal anti -inflammatory drugs (NSAIDs) help reduce pain and swelling symptoms.

    Sjogren's syndrome treatment by changing lifestyle

    Một số biện pháp liên quan đến vấn đề sinh hoạt hằng ngày, thói quen chăm sóc cơ thể đã được kể trên cũng góp phần cải thiện các triệu chứng của bệnh và dự phòng các biến chứng nặng nề hơn.

    See also:

  • dry eye: Causes, symptoms, diagnosis and treatment
  • bad breath: Causes, symptoms, diagnosis and Article Treatment
  • How many liters of saliva will be secreted throughout the life?

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