Transformer

Transformer's disease overview

What is

What is lymphatic disease?

Lymphatic disease is a common type of dermatological disease in which skin pigmentation cells are destroyed, thereby changing skin color. The disease manifests itself by the inlaid, hypogonedia compared to the surrounding skin, no itching, no scales, clear limit. This is a benign disease, not contagious, and has a lot of aesthetic influence.

In Vietnam, there is no official statistics on the incidence. Lymphatic disease may meet all ages and gender. The most common age is from 10-30, more than 50% occurs before the age of 20 and may experience lymphatic disease in children . The disease is heavily distributed in tropical countries and in colored people. The disease has a family nature but has no studies have confirmed that transformer is genetic .

The disease greatly affects the quality of life and psychology of the patient, especially in the complexity of the cause as well as the difficulties in treatment.

There is no accurate research data on the transformer rate in Vietnam. In the United States, the disease rate accounts for 1%. The disease has a family nature in about 30% of cases. Most patients are healthy, combined with other autoimmune diseases such as thyroid disease, diabetes, anemia, and marrow. Therefore, in addition to aesthetic aspect, attention should be paid to the accompanying pathologies.

Causes of Transformer's disease

Causes of lymphatic diseases are not well known. The only thing is for sure that the transformer appears due to the decrease in the quantity and quality of skin pigment cells in the sick skin. Some hypotheses suggest that the dysfunction may be due to the effects of autoimmune disease or possibly genetic, related to mutations in the DR4, B13 or BW35 genes of HLA. Self -antibodies view pigment cells as antigens and fight them, destroy pigment cells and reduce melanin pigment production. About 20-30% of white variation patients have antibodies against cells of the thyroid gland, adrenal glands, genital glands, and hepatopancreas, so some of the white vaginal patients have attached diseases related to organs. above.

Symptoms of Transformer's disease

The main manifestation of lymphatic disease is the inlaid, white patches, clear limits, loss of skin pigmentation compared to surrounding skin areas due to skin pigment cells there Also or have stopped working. The common location of the transparent plaques is the open areas, exposed to sunlight such as hands, legs, face, lips.

The skin on the white transformers is still normal, no atrophy, no scales, the feeling on the skin is not changing, no itching pain, no numbness. The hair on the white vaginal crowd is also white.

Depends on the lymphatic disease , discolored skin patches may appear in a different way:

Body transforming body: This is the most common disease. The transformers often appear in many parts of the body and have symmetrical nature

Bach transforming segmentation: usually manifests one or one part of the body. This form tends to appear in younger patients, only progressing within 1 to 2 years.

Local transformer: only occurs in a few positions on the body.

It is difficult to predict the progression of the disease. Sometimes the transformer will be localized without treatment. In most cases, the skin loss of pigmentation will spread. Chronic disease progresses, there are severe severe, damage often in the summer, decreasing in the winter.

The younger the patient, the shorter the prognosis time and the shorter the disease and the more hope. On the contrary, the patient, the older, the longer the disease is, the worse the results of the treatment.

Transmission route of Transformer's diseaseTransformer

Is lymphatic disease contagious?

This is a skin disease that does not spread completely to those around them, including those who are close to the sick.

People at risk for Transformer's disease

The risk of lymphatic disease includes people with severe psychological trauma, sunburn or tanned.

Prevention of Transformer's disease

    • Diagnostic measures for Transformer's disease

    Diagnosis of lymphatic disease is mainly based on prehistoric exploitation and clinical symptoms. The medical examination and questioning helps eliminate some other diseases such as dermatitis or psoriasis. The doctor uses UV light on the skin to determine if the patient has dyspepsia no.

    Besides, the doctor may appoint to do other tests such as:

  • Biopsy a piece of skin in the lesions
  • Blood to search for autoimmune causes such as anemia or diabetes

    • Transformer's disease treatments

    Canhi disease be cured?

    Due to the cause of lymphatic disease has not been understood, there is no specific treatment. Currently, treatment is still difficult, the treatment has just stopped at symptoms.

    Drugs
  • The drug group has the effect of increasing the touch of body light or on the spot such as psoralen preparations such as Meladinin, Melagenin combined with the UV wavelength or long wavelength projection in the region Damage. The side effects of this drug group include anorexia, increased liver enzymes, jaundice. The drug applied on the spot can make the white variations burn water so it can be used in combination with anti -inflammatory drugs, anti -allergies, immunosuppressive inhibitors (corticosteroids, immuran, cyclosporin). The drug is prescribed in patients 12 years of age.
  • corticosteroids are topical options to coordinate with other therapies such as CO2 laser, narrow universal UVB, vitamin D3 derivatives ... bring better treatment effect, most most are cases of localized transformer. Along with the anti -inflammatory effect, this drug group also has the effect of inhibiting the immune system of the patient by the effect of reducing the number of cytokines. Therefore, the drug reduces the activity of antibodies that cause pigment disorders. Corticosteroids have many different drug groups, the choice of specific drugs depends on the location of the pigment disorders. Hydrocortisone is given priority to use for face lesions. Other positions on the skin should choose corticosetroid group III, IV. However, because of the side effects, the drug is limited to lymphatic disease in children , and should not be used for more than 2 months.

    • Sunscreen drugs: In white patients, the quality as well as the amount of pigment cells decrease, so the body's ability to protect the harmful effects of sunlight. Causes a decline in body protection under the impact of sunlight. In addition to the use of topical sunscreen, patients should combine the form of sunscreen to avoid sunburn in pigmented skin areas. Sunscreen also helps reduce color contrast between healthy skin and disease, avoid loss of aesthetics, as well as avoid Koebner phenomenon that damages the skin. Psychological advice:

    Lymphatic disease causes many impacts on the psychology of patients, causing decrease in quality of life. Some problems that patients face include psychological abnormalities, sexual difficulties, concerns, anxiety and coordination of the above issues.

    Therefore, the role of psychological counseling in the treatment of white variables is extremely important, it should be emphasized so that the patient understands the disease only affects aesthetics but is less dangerous to life. <

    Skin pigmentation cell transplant:

    This is a new method in the treatment of lymphatic disease but requires high cost and technology, so it is not widely applied.

    In short, white variation is a benign skin disease that can be seen at any age with a uniform rate in both sexes. The treatment of disease is a long -term process that needs perseverance between patients and doctors. Patients need to maintain psychology, avoid pessimism worries to make the disease worse.

    See also:

  • Human albinism is caused by any mutations? /Li>
  • white products: Causes, symptoms, diagnosis and treatment

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