Does Otezla cause depression?

Drugs.com

Official answer

by Drugs.com

Otezla may lower a person's mood, cause depression, and increase suicidal thoughts. Research has shown approximately 1% of people treated with Otezla for psoriatic arthritis reported depression or a depressed mood compared with 0.8% of those treated with an inactive treatment. The risk was slightly higher for those with psoriasis, with 1.3% reporting a lower mood compared with 0.8% treated with placebo. 0.3% of people with psoriatic arthritis and 0.1% of people with psoriasis discontinued treatment because of the depression. There was not any difference in the rates of depression for those treated with Otezla for Behçet’s disease.

Symptoms of depression include feelings of sadness, hopelessness, or worthlessness; a loss of interest in activities that were previously enjoyable; and appetite or sleep changes. Tell your doctor if you have ever had problems with mood or depression before starting Otezla. Contact your doctor immediately if you have any signs of worsening depression, suicidal thoughts, or other mood changes. Your family members should also help to monitor you for these changes.

Related medical questions

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Popular Keywords