Does Skyrizi cause cancer?
Skyrizi has no warnings or precautions for malignancy (cancer) in its product label and cancer is not listed as a serious or common side effect.
Very few cases of cancer were reported in plaque psoriasis clinical trials and may not have been treatment-related.
Do patients with psoriasis get cancer more often?
A large review published in JAMA Dermatology looked at over 58 studies from 2018 to 2019. Researchers found that psoriasis itself can be linked with an increased risk of many types of cancer, such as colon, kidney, throat (laryngeal), esophageal, liver, oral, pancreatic and blood cancers like lymphoma and non-Hodgkin lymphoma.
Skyrizi (risankizumab-rzaa) is used for the treatment of plaque psoriasis in adults who may benefit from taking injections or pills (systemic therapy) or treatment using ultraviolet or UV light (phototherapy). It is also approved to treat active psoriatic arthritis and moderate-to-severe Crohn's disease in adults.
Skyrizi works by blocking interleukin-23 (IL-23) and lowering the inflammatory response.
Related: Skyrizi side effects (in more detail)
Other treatments approved by the FDA to treat plaque psoriasis include:
This is not all the information you need to know about Skyrizi (risankizumab-rzaa) for safe and effective use and does not take the place of talking to your doctor about your treatment. Review the full Skyrizi product information here, and discuss this information and any questions you have with your doctor or other health care provider.
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