Does Xolair cause hair loss?
Hair loss (alopecia), has been reported in Xolair clinical studies in at least 2% of people with chronic hives. Hair loss has also been noted in several case reports with Xolair. The hair loss effect appears to be transient, lasting from 3 to 4 months. Due to limited data, the exact cause of hair loss or how often it occurs is not known.
Xolair is approved to treat asthma, nasal polyps and chronic hives (also called chronic spontaneous urticaria). Xolair is a subcutaneous (under the skin) injection and is typically used when other treatments have not been effective to control your symptoms. It works by inhibiting the binding of the IgE antibody (or immunoglobulin) to IgE receptors on mast cells and basophils.
Is alopecia reported with Xolair?
In two separate case reports, alopecia (hair loss) has also been reported with Xolair treatment.
Three women, 38, 62 and 70 years of age, with chronic spontaneous urticaria received treatment with omalizumab (Xolair) 300 mg. They had failed treatment with non-sedating antihistamines, ranitidine and montelukast. One patient reported having Hashimoto’s thyroiditis, which has been associated with hair loss, but was not in this case report.
In another case report, a 27-year woman was admitted to the hospital with chronic spontaneous urticaria for 3 weeks. She was admitted to the hospital but had no effect with non-sedating antihistamines, prednisolone, and montelukast (Singulair) treatment for her hives.
Does Xolair cause alopecia areata?
Alopecia areata has also been reported with the use of Xolair for chronic hives.
Alopecia areata, an autoimmune disorder, leads to hair loss with circular patches and can occur when the immune system attacks the hair follicles.
Bottom Line
This is not all the information you need to know about Xolair (omalizumab) for safe and effective use and does not take the place of your doctor’s directions. Review the full product information and discuss this information and any questions you have with your doctor or other health care provider.
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