Does Xyrem cause weight gain or loss?

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Official answer

by Drugs.com
Xyrem (sodium oxybate), which is used to treat cataplexy or excessive daytime sleepiness (EDS) in patients 7 years of age and older with narcolepsy, can cause weight loss. Weight loss is reported to be an adverse reaction associated with Xyrem treatment, but it is also seen as a beneficial effect of the drug because narcolepsy is linked to weight gain and obesity.

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