How does Empaveli compare to Soliris?

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Official answer

by Drugs.com
Empaveli is a brand name for pegcetacoplan which is a PEGylated 40kDa polyethylene glycol linear small molecule that acts as a C3 complement inhibitor and Soliris is a brand name for eculizumab which is a monoclonal antibody that specifically binds to the complement protein C5. Empaveli is given by subcutaneous infusion and people can be taught how to self-administer it at home. Soliris is given by infusion under the guidance of a healthcare professional every 2 weeks (after the initial dosing schedule) although most patients are encouraged to switch from Soliris to Ultomaris which only requires 7 infusions in adults a year.

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