How is Activase (alteplase) given/administered?
How Activase is given or administered depends upon the patient’s weight and what it is being used to treat (such as a stroke, pulmonary embolism, or myocardial infarction). For example, when used to treat a heart attack (myocardial infarction), there are two Activase dose regimens, an accelerated and a 3-hour regimen, with different recommendations depending on if the patient is over 67kg or not.
FDA-approved indications for Activase include pulmonary embolism, myocardial infarction with ST-segment elevation (STEMI), ischemic stroke when given within 3 hours of the start of symptoms, and re-establishment of patency in occluded intravenous (IV) catheters.
Recommended administration of Activase for pulmonary embolism (PE)
Recommended administration of Activase for myocardial infarction with ST-segment elevation (STEMI) (heart attack)
Accelerated regimen
3-hour regimen
Recommended administration of Activase for Acute Ischemic Stroke
Recommended administration of Activase for IV Catheter Occlusion
Related medical questions
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- How is Activase (alteplase) given/administered?
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