How is Lartruvo administered?
The approved recommended dosage of Lartruvo is 15 milligrams per kilogram (mg/kg) as an intravenous (IV) infusion given over 60 minutes on Days 1 and 8 of each 21-day cycle until disease progression or unacceptable toxicity.
Patients should be premedicated with diphenhydramine (25 to 50 mg intravenously) and dexamethasone (10 to 20 mg intravenously), prior to Lartruvo on Day 1 of cycle 1. For the first 8 cycles, Lartruvo is administered with doxorubicin. Refer to doxorubicin prescribing information for dosing, and dose modifications.
Lartruvo (olaratumab) injection is used in combination with doxorubicin for the treatment of adult patients with soft tissue sarcoma (STS) who cannot be cured with radiation or surgery. The soft tissue sarcoma is a histologic subtype for which an anthracycline-containing regimen is appropriate.
How does Lartruvo work?
Lartruvo works as a platelet-derived growth factor receptor alpha (PDGFR-α) blocking antibody to help slow or stop tumor growth.
In clinical studies submitted to the FDA, Lartruvo was shown to lengthen survival time. Patients who received Lartruvo with doxorubicin had a statistically significant improvement in overall survival: the median survival was 26.5 months compared to 14.7 months for patients who received doxorubicin alone.
Common side effects included nausea, fatigue, low white blood cells (neutropenia), and muscle pain, among others.
This is not all the information you need to know about Lartruvo (olaratumab) for safe and effective use and does not take the place of talking to your doctor about your treatment. Review the full Lartruvo information here, and discuss this information and any questions you have with your doctor or other health care provider.
Related medical questions
- What is the chemo drug called the Red Devil?
- What is the strongest chemotherapy drug for breast cancer?
- How is Lartruvo administered?
- What is the chemo drug called the Red Devil?
- What is the strongest chemotherapy drug for breast cancer?
- How is Lartruvo administered?
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Popular Keywords
- metformin obat apa
- alahan panjang
- glimepiride obat apa
- takikardia adalah
- erau ernie
- pradiabetes
- besar88
- atrofi adalah
- kutu anjing
- trakeostomi
- mayzent pi
- enbrel auto injector not working
- enbrel interactions
- lenvima life expectancy
- leqvio pi
- what is lenvima
- lenvima pi
- empagliflozin-linagliptin
- encourage foundation for enbrel
- qulipta drug interactions