How long can I take Sotyktu for?
Sotyktu is an oral tablet given daily that has been shown to work for at least 2 years in plaque psoriasis studies. It is meant to be taken on a daily basis, but how long you take this medicine will depend on your individual response to treatment. Continue your treatment as long as recommended by your healthcare provider.
Long-term Efficacy Studies of Sotyktu
Following the 52-week POETYK PSO trials, patients could enroll in the longer-term POETYK PSO-LTE trial and receive open-label Sotyktu 6 mg once daily.
How fast does it work?
Sotyktu has been shown to be effective in 16 weeks when compared to a placebo agent. Of the 262 Sotyktu patients in the long-term analysis, 171 had achieved 75% improvement in skin symptoms (PASI 75) at Week 16 of the POETYK PSO-1 trial, and among these patients, efficacy was maintained for up to 112 weeks (over 2 years) including response rates for:
What does Sotyktu treat and how do you take it?
Sotyktu is used in adults 18 years and older to treat moderate-to-severe plaque psoriasis that is a candidate for systemic therapy or phototherapy. The recommended dosage is 6 mg taken orally once daily, with or without food. Be sure not to cut, crush, or chew the tablets because it can affect how this medication is absorbed and works.
This medicine is safe to take if you have kidney problems or mild-to-moderate liver problems. If you have severe liver disease, you may not be able to use this medicine.
Tell your doctor and pharmacist about all of the medications you take, including prescription, over-the-counter (OTC), vitamins or herbal or dietary supplements. You may not be able to use certain other immunosuppressant medicines or live vaccines with Sotyktu.
Sotykto (deucravacitinib) is manufactured by Bristol Myers Squibb’s and was first approved in September 2022.
Always take Sotyktu, pronounced "soh-tik-too", exactly as prescribed by your healthcare provider.
Are side effects common with Sotyktu?
The most common side effects seen in at least 1% of patients in clinical studies were:
Warnings and precautions include allergic reactions (some may be serious), increased risk of infections, increased risk of developing malignancies including lymphomas; increased risk of developing rhabdomyolysis (severe muscle damage), and changes in laboratory values.
How does Sotyktu work?
Sotyktu works by blocking an immune system enzyme (protein) called TYK2 that can lead to the inflammation (swelling, redness) seen in plaque psoriasis. Blocking TYK2 may improve psoriasis symptoms and lead to clearer skin. Symptoms of psoriasis include pain, itching, stinging, burning, and skin tightness.
Does Sotyktu work for scalp psoriasis?
Yes, studies have shown that Sotyktu is effective for psoriasis that occurs on the scalp when compared to Otezla (apremilast), another oral psoriasis treatment and a placebo (an inactive treatment).
This is not all the information you need to know about Sotyktu (deucravacitinib) for safe and effective use and does not take the place of your doctor’s directions. Review the full product information and discuss any questions you have with your doctor or other health care provider.
Related medical questions
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