How long does Cimzia take to work?
Cimzia injection can work as fast as 1 or 2 weeks in some people for conditions such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and non-radiographic axial spondyloarthritis. Its full effectiveness can range from 4 months to 1 year based on your specific medical condition.
Improvements in joint worsening, daily activities and quality of life measures may also occur with Cimzia treatment.
Cimzia is classified as an anti-tumor necrosis factor (TNF) biologic. It is administered as a subcutaneous (under the skin) injection.
Cimzia (certolizumab pegol) is approved by the FDA to treat:
In clinical studies, Cimzia was evaluated against a placebo, an inactive treatment used as a comparison. Some studies also included NSAIDs, corticosteroids and DMARDS like methotrexate in the Cimzia and placebo groups.
Your results may vary from the following study results. Talk to your doctor to learn more about how long it may take for Cimzia to improve your symptoms.
Clinical studies: How long for Cimzia to work?
Rheumatoid arthritis
Dosing: In rheumatoid arthritis, the Cimzia recommended dose is 400 mg initially and at Weeks 2 and 4, followed by 200 mg every other week. For maintenance dosing, 400 mg every 4 weeks can be considered.
Psoriatic Arthritis
Dosing: In psoriatic arthritis, the Cimzia recommended dose is 400 mg initially and at Weeks 2 and 4, followed by 200 mg every other week. For maintenance dosing, 400 mg every 4 weeks can be considered.
Ankylosing Spondylitis
Dosing: For ankylosing spondylitis (AS), Cimzia is given as 400 mg initially and at weeks 2 and 4, followed by 200 mg every other week or 400 mg every 4 weeks.
Plaque Psoriasis
Dosing: In plaque psoriasis, Cimzia is given as 400 mg every other week. For some patients (with body weight ≤ 90 kg), a dose of 400 mg initially and at Weeks 2 and 4, followed by 200 mg every other week may be considered.
Crohn’s disease
Dosing: In Crohn’s disease, Cimzia is given as 400 mg initially and at Weeks 2 and 4. If a clinical response occurs, follow with 400 mg every four weeks
Non-radiographic axial spondyloarthritis (nr-axSpA)
Dosing: For non-radiographic axial spondyloarthritis, a Cimzia dose of 400 mg is given initially, and at weeks 2 and 4, followed by 200 mg every other week or 400 mg every 4 weeks.
This is not all the information you need to know about Cimzia (certolizumab pegol) for safe and effective use and does not take the place of your doctor’s directions. Review the full product information and discuss this information and any questions you have with your doctor or other health care provider.
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