How long does Epclusa stay in your system?

Drugs.com

Official answer

by Drugs.com

Epclusa stays in your system approximately 3 days after the last dose. This is calculated by looking at the half-life of velpatasvir which is 15 hours and that of sofosbuvir, which is 0.5 hours. The half-life is the time it takes for 50% of a medicine to be eliminated from the body. Research has shown that it takes 4 to 5 half-lives for a medicine to be fully cleared from the body which calculates out to 60 to 75 hours or 2.5 to 3.1 days for Epclusa. There are no active metabolites of velpatasvir or sofosbuvir that may prolong this half-life, and its clearance is not significantly affected by liver disease or mild-to-moderate kidney impairment.

If you are still experiencing side effects from Epclusa more than 5 days after you have stopped taking it, talk with your doctor. It can take a while for your body to recover from hepatitis C once you have finished a course of Epclusa. Talk to your doctor if you have any concerns.

Related medical questions

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Popular Keywords