How long does it take for Degarelix to work?

Drugs.com

Official answer

by Drugs.com

Degarelix works almost immediately, with an initial injection of degarelix causing a drop in testosterone levels of 88% after 1 day. Within 3 days, levels had dropped by 94%, and by 28 days, 98%. When given every 28 days, levels of testosterone remain at least 98% below normal.

The initial dose of degarelix is 240 mg (given as two subcutaneous injections of 120 mg) and the maintenance dose is 80mg given once every 28 days. When given using this dosage regimen, degarelix is effective in achieving and maintaining testosterone suppression below the castration level of 50 ng/dL.

Degarelix works by binding to pituitary GnRH receptors, reducing the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), and subsequently testosterone. It may be used for the treatment of advanced prostate cancer and also for medical castration. Degarelix belongs to the class of medicines known as GnRH receptor antagonists.

Related medical questions

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Popular Keywords