How much does Entyvio cost per month?

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Official answer

by Drugs.com

The list price for a 30-day supply of intravenous (IV) or subcutaneous (SC) Entyvio is $4,380.01 or $52,560.12 per year. Your final cost will depend upon your insurance coverage or copays. Entyvio is a prescription medicine used to treat patients with ulcerative colitis or Crohn‘s disease.

Patients with private insurance or government sponsored plans will have different costs based on formulary coverage, copay tiers, or any discounts. You may also have costs associated with administration of the IV formulation.

You may also be eligible for EntyvioConnect, the patient financial assistance program from Takeda Pharmaceuticals. You can contact them at 1-844-368-9846. If you qualify, you may pay as little as $5 per dose every 8 weeks or Takeda can help you find financial assistance.

Entyvio (vedolizumab) is approved by the FDA to treat adults with moderate to severe ulcerative colitis (UC) or Crohn‘s disease (CD), two inflammatory bowel diseases that affect your digestive tract. It's is classified as an integrin receptor antagonist that works by blocking certain cells to help decrease inflammation in the gastrointestinal tract.

How is intravenous (IV) or subcutaneous (SC) Enytvio given?

Intravenous (IV) administration

Entyvio is given as a 300 mg intravenous (IV) infusion into your vein for both ulcerative colitis (UC) and Crohn's disease (CD). IV infusions are given though a needle into a vein in your arm, usually at local infusion clinic, hospital, doctor's office or at home.

Talk to your doctor and insurance company about which location may be best and most affordable for you.

The suggested IV dose in UC and CD is 300 mg infused IV over approximately 30 minutes at Week 0, Week 2, and Week 6, then every eight weeks thereafter. A healthcare provider will administer the IV infusions.

Entyvio infusions take about 30 minutes each time, but your entire clinic visit might take a couple of hours. You can usually go back to your normal activities after the infusion.

After the first year, you will receive six Entyvio IV infusions per year.

Subcutaneous (under the skin) injection for UC

In addition to the IV formulation, in 2023 the FDA approved Entyvio (vedolizumab) given as a subcutaneous (SC) injection for maintenance treatment of UC. Subcutaneous injections are given just under skin using a short needle. You or a caregiver can learn to administer these injections at home so you don't have to visit the clinic.

Entyvio is used for maintenance therapy only in adults with moderately-to-severely active ulcerative colitis (UC) after intravenous (IV) induction therapy with Entyvio. Patients or caregivers may inject Entyvio at home after training on the subcutaneous injection technique.

  • Following the first two IV doses administered by a healthcare provider at Week 0 and Week 2 in UC, Entyvio may be switched to SC injection (given under the skin in the thigh, abdomen, or upper arm area) at Week 6.
  • The recommended SC dosage in UC starting at Week 6 is 108 mg administered every 2 weeks.
  • Patients already in clinical response or remission beyond Week 6 may also be switched from the IV infusion to SC injection.
  • New SC dosage forms include a single-dose pre-filled pen and a single-dose prefilled syringe.

    Does insurance pay for Entyvio?

    If you have insurance, your copay for Entyvio will vary based on your formulary coverage or the type of government insurance you have. If you have private commercial insurance, you may be able to get Entyvio for as little as $5 per dose. If you do not have insurance, Takeda may still be able to offer you financial assistance.

    Patients who receive governmental-sponsored insurance, such as Medicare, Medicaid, or TriCare are not eligible for the $5 copay program. However, you may still be able to get assistance through an independent copay foundation.

    Takeda Pharmaceuticals offers a patient assistance program called EntyvioConnect that offers financial assistance, co-pay support, nurse resources and useful tips to help you manage your condition.

    You can contact EntyvioConnect at 1-844-ENTYVIO (1-844-368-9846), Monday to Friday, from 8am to 8pm ET (except holidays).

    Bottom Line

    Entyvio costs $$4,380.01 for a 30-day supply of intravenous (IV) or subcutaneous (SC) medication. However, most patients do not pay this price. Your price will vary based on your insurance type, formulary coverage and copay tier.

    Intravenous formulations are given at a clinic, in the hospital or doctor's office or even at home, if approved by your doctor and insurance. Subcutaneous injections of Entyvio can be self-administered or given by a caregiver at home after training on the injection technique.

    If you don't have insurance or need other financial assistance, you can speak to a representative at Takeda Pharmaceuticals who can explain your options. Call 1-844-368-9846.

    This is not all the information you need to know about Entyvio (vedolizumab) for safe and effective use and does not take the place of your doctor’s directions. Review the full product information and discuss this information and any questions you have with your doctor or other health care provider.

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