Is Mavenclad a chemotherapy drug?

Drugs.com

Official answer

by Drugs.com

No, Mavenclad is not a chemotherapy (cancer) drug. It is an oral purine antimetabolite approved for the treatment of relapsing forms of multiple sclerosis (MS), to include relapsing-remitting disease and active secondary progressive disease, in adults. Mavenclad tablets are taken by mouth and are given as two yearly treatment courses.

Mavenclad is not recommended for MS patients with clinically isolated syndrome or as a first-line agent due to its safety profile.

Multiple sclerosis (MS) is a chronic, inflammatory, autoimmune disease of the nervous system that alters signals between the brain and other parts of the body. Symptoms of MS typically first appear in patients between 20 and 40 years of age.

How does Mavenclad work?

Mavenclad (cladribine) is thought to work by selectively targeting B and T lymphocytes (types of white blood cells) that may be involved in the disease process of relapsing multiple sclerosis (MS).

  • Mavenclad temporarily lowers the number of these white blood cells in your body to help decrease the number of MS relapses and reduce the progression to disability.
  • After receiving Mavenclad, your white blood cells should recover over several months or longer.
  • Lowered white blood cells can increase your risk for infections. Your doctor will monitor your health and white blood cell counts before, during and after treatment, and as needed.

    • Treatment with Mavenclad may increase your risk of developing cancer. Talk to your doctor about this risk before you start treatment. Follow your healthcare provider instructions about cancer screenings you need to schedule.

    You should not take Mavenclad if you

  • have cancer (a malignancy)
  • are pregnant, plan to become pregnant, or are a woman of childbearing age or a man able to father a child and you are not using birth control. Mavenclad may cause birth defects if used during pregnancy.
  • are human immunodeficiency virus (HIV) positive
  • have active infections, including tuberculosis (TB), hepatitis B or C
  • are allergic to cladribine
  • are breastfeeding

    • What is chemotherapy?

    Chemotherapy (“chemo”) is used in the treatment of cancer and kills rapidly dividing cancer cells directly. Chemotherapy can be used with other treatments, such as surgery, radiation or immunotherapy.

    Some drugs used for chemotherapy are also classified as purine antimetabolites. For example, mercaptopurine is used to treat the blood cancer leukemia.

    Azathioprine is also a purine antimetabolite, but it is used to help prevent kidney transplant rejections and in the treatment of rheumatoid arthritis.

    This is not all the information you need to know about Mavenclad (cladribine) for safe and effective use and does not take the place of talking to your doctor about your treatment. Review the full Mavenclad information here, and discuss this information and any questions you have with your doctor or other health care provider.

    Related medical questions

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

    Popular Keywords