Oxycodone vs OxyContin - What's the difference?
What is the difference between oxycodone and Oxycontin?
Oxycodone and Oxycontin are essentially the same substance, but the main difference is that Oxycontin is a long-acting form of oxycodone. Oxycontin releases oxycodone slowly and continuously over 12 hours and only needs to be given twice a day. Oxycodone is short-acting and relieves pain for about 4 to 6 hours so needs to be given four to six times a day to provide all-day pain relief. Oxycodone is usually given for acute pain, such as that following surgery or trauma, whereas Oxycontin may be given for chronic or long-term pain, such as that caused by cancer. Oxycontin should only be considered in those with chronic severe pain that have already found a trial of oxycodone to be beneficial.
Oxycontin may also be called a controlled-release or extended-release tablet. It has been designed so that the active drug, oxycodone, is released in two phases. The first layer allows for the initial rapid release of oxycodone from the surface of the tablet, providing pain relief within about 20 minutes. The inner layer slowly releases the remainder of the oxycodone over 12 hours.
The decision to prescribe oxycodone and Oxycontin should not be taken lightly because these medications have been associated with long-term physical and psychological dependence, even when prescribed for conditions as innocuous as dental pain.
What are the similarities between oxycodone and Oxycontin?
Which is more effective? Oxycodone or Oxycontin?
The effectiveness of oxycodone and Oxycontin depends on what a doctor has prescribed the medicine for. For people with chronic, severe pain, that lasts all day, Oxycontin may be preferred because with twice-daily dosing its effects can last for 24 hours. For people with acute pain, such as that following surgery or trauma, oxycodone is preferred, because it works quickly and is available in combination with other pain-relieving medicines, such as acetaminophen or ibuprofen.
Oxycodone may be used to treat severe pain which is uncontrolled by alternative, nonopioid, analgesics, such as that caused by:
Oxycontin may be used to treat pain that is severe enough to require daily, around-the-clock, long-term treatment, and for which no other treatment (such as nonopioid medications or immediate-release opioids) has proved adequate. It should not be used on an “as needed” basis. There is a greater risk of overdose and death with long-acting opioid formulations (also called extended-release or controlled-release) formulations such as Oxycontin.
Are there any differences in side effects between oxycodone and Oxycontin?
Because oxycodone and Oxycontin contain the same medicinal ingredient, they have similar side effects, such as:
Oxycodone and Oxycontin may also increase the risk of seizures in people with seizure disorders.
Respiratory depression is more likely to happen during the first 1 to 3 days of oxycodone or Oxycontin treatment, after a dosage increase, or if too much oxycodone or Oxycontin is taken. Children, the elderly, the frail, or those with pre-existing respiratory conditions are more at risk. Respiratory depression can be life-threatening or cause death.
Stopping either oxycodone or Oxycontin suddenly in a person who has been taking it a while and become physically dependent on it may lead to withdrawal symptoms such as restlessness, pupil dilation, watery eyes and a runny nose, sweating, muscle aches, insomnia, irritability, and gastrointestinal complaints, such as abdominal pain, nausea, vomiting, or diarrhea. Babies born to mothers who are physically dependent on oxycodone or Oxycontin will also be physically dependent.
Which has more drug interactions? Oxycodone or Oxycontin?
Because oxycodone and Oxycontin contain the same medicinal ingredient, they have similar interactions, such as:
Oxycodone | Oxycontin | |
---|---|---|
Used for: | Moderate-to-severe acute pain such as that following surgery or from trauma | Moderate-to-severe chronic pain such as that associated with cancer or other terminal conditions |
Is a generic available? | Yes | Yes |
Brands available | Oxaydo OxyIR OxyFast Roxicodone | Oxycontin Xtampza ER |
Formulations | Immediate-release capsules Immediate-release tablets Immediate-release solution | Controlled-release tablets |
Dosage | Every four to six hours | Every 12 hours |
Duration of treatment | Short-term | Long-term |
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- Oxycodone vs OxyContin - What's the difference?
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