Ozempic vs Wegovy: What's the difference between them?

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Official answer

by Drugs.com

Ozempic and Wegovy are the two brand names that Novo Nordisk uses to market injectable semaglutide.

Ozempic is used to treat type 2 diabetes and prevent major cardiovascular problems in certain patients, while Wegovy is used for chronic weight management and helps with weight loss.

The table below outlines the specific conditions that Ozempic and Wegovy are used to treat and the dosage forms and strengths each semaglutide-containing product comes in.

Ozempic Wegovy
Generic name Semaglutide Semaglutide
Marketed by Novo Nordisk Novo Nordisk
Dosage form and strength Injection - 2 mg / 3 mL (0.68 mg/mL)
  • Single-patient-use pens (delivering 0.25 mg or 0.5 mg per injection)
    • Injection - 4 mg / 3mL (1.34 mg / mL)
  • Single-patient-use pen (delivering 1 mg per injection)

    • Injection - 8 mg / 3 mL (2.68 mg / mL)

  • Single-patient-use pen (delivering 2 mg per injection)

    • Dose is increased slowly up to a maximum of 2 mg weekly if required.

    Each box comes with NovoFine Plus needles.

    		 Injection - pre-filled, single-dose pen (delivering doses of 0.25 mg, 0.5 mg, 1 mg, 1.7 mg or 2.4mg).

    Initiate at 0.25 mg once weekly for 4 weeks. Dose is increased slowly until a maintenance dose of 2.4 mg weekly is reached.
    Uses
  • As an add on to diet and exercise to improve glycemic control in adults with type 2 diabetes
  • To reduce the risk of major adverse cardiovascular events in adults with type 2 diabetes and established cardiovascular disease
    		•  An an add-on to a reduced calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index (BMI) of:
  • 30kg/m2 or greater (obesity) or
  • 27kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition, such as high blood pressure, type 2 diabetes and dyslipidemia

    • As an adjunct to a reduced calorie diet and increased physical activity for chronic weight management in pediatric patients aged 12 years and older with:

  • an initial BMI at the 95th percentile or greater for age and sex (obesity).
    		•
    First approved in US 2017 2021

    For more information on Wegovy, Ozempic and Rybelus, visit here: What is the difference between Wegovy, Ozempic and Rybelus?

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