What are the biosimilars of Herceptin?
What are the biosimilars of Herceptin?
Herceptin (trastuzumab) is the original brand of trastuzumab, a biological medicine used to treat specific types of breast and gastric cancer, in specific patients and used in conjunction with prescribed treatment regimes.
What is the difference between generic and biosimilar medicines?
The biosimilars of Herceptin are:
Table comparing Herceptin to its Biosimilars
Brand name | Herceptin | Herzuma | Kanjinti | Ogivri | Ontruzant | Trazimera |
Active ingredient name | trastuzumab | trastuzumab-pkrb | trastuzumab-anns | trastuzumab-dkst | trastuzumab-dttb | trastuzumab-qyyp |
Company | Genentech | Celltrion | Allergan Amgen | Mylan | Samsung Bioepis | Pfizer |
Approval date (FDA) | 25 September 1998 | 14 December 2018 | 13 June 2019 | 1 December 2017 | 18 January 2019 | 11March 2019 |
Interchangeable? | No | No | No | No | No | No |
Treatment* | Adjuvant breast cancer, Metastatic breast cancer, Metastatic gastric cancer | Adjuvant breast cancer, Metastatic breast cancer, Metastatic gastric cancer | Adjuvant breast cancer, Metastatic breast cancer, Metastatic gastric cancer | Adjuvant breast cancer, Metastatic breast cancer, Metastatic gastric cancer | Adjuvant breast cancer, Metastatic breast cancer, Metastatic gastric cancer | Adjuvant breast cancer, Metastatic breast cancer, Metastatic gastric cancer |
Form | 150mg Single use vial, 420mg Multiple use vial | 150mg Single use vial, 420mg Multiple use vial | 150mg Single use vial, 420mg Multiple use vial | 150mg Single use vial, 420mg Multiple use vial | 150mg Single use vial, 420mg Multiple use vial | 150mg Single use vial, 420mg Multiple use vial |
Administration route | intravenous infusion | intravenous infusion | intravenous infusion | intravenous infusion | intravenous infusion | intravenous infusion |
* Treatment is only indicated in these conditions for selected patients who have a specific type of cancer, who will be using specific treatment regimens, and patient selection can be dependent on previously used treatment options
What is a biological medicine?
What is a reference product?
What does biosimilar mean?
What does ‘interchangeable product’ mean?
The biosimilars of Herceptin and NOT interchangeable.
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