What cancers are treated with Xalkori?
Xalkori treats three types of cancers with genetic mutations: non-small cell lung cancer (NSCLC) anaplastic large cell lymphoma (ALCL), a type of blood cancer, and anaplastic lymphoma kinase (ALK)-positive inflammatory myofibroblastic tumors (IMT), a type of solid tumor that may occur in the lungs, abdomen or pelvis area.
Xalkori blocks the activity of the proteins in tumors that have the gene alterations. This effect can help the cancer from growing and spreading.
Xalkori is an oral prescription medicine made by Pfizer. It is usually taken as one capsule or oral pellets twice per day, but you may need a different dose. Some doses may be based on your weight. Always follow your doctor's instructions exactly.
Non-small cell lung cancer (ALK+ or ROS1+)
Xalkori (crizotinib) is used to treat adult patients with metastatic non-small cell lung cancer (NSCLC) due to a genetic defect. Metastatic means the cancer has spread to other parts of the body.
Anaplastic large cell lymphoma (ALK+)
Xalkori is also approved to treat children 1 year of age and older and young adults with systemic anaplastic large cell lymphoma (ALCL) that is ALK+. It is used when the cancer has returned (relapsed) or a previous treatment did not work or is no longer working (refractory).
ALK+ inflammatory myofibroblastic tumors (IMT)
In July 2022, the FDA approved Xalkori for the treatment of anaplastic lymphoma kinase (ALK)-positive inflammatory myofibroblastic tumors (IMT) for adults and children 1 year of age and older, with tumors that cannot be surgically removed, have returned, or have failed other treatments.
This is not all the information you need to know about Xalkori (crizotinib) for safe and effective use and does not take the place of talking to your doctor about your treatment. Review the full Xalkori information here, and discuss this information and any questions you have with your doctor or other health care provider.
Related medical questions
- How effective is Xalkori?
- Will I need to use Xalkori long term?
- Is Xalkori the same as Opdivo or Keytruda?
- Do I need any blood tests while taking Xalkori?
- How long does it take for Xalkori to work?
- How to pronounce Xalkori?
- What cancers are treated with Xalkori?
- How effective is Xalkori?
- Will I need to use Xalkori long term?
- Is Xalkori the same as Opdivo or Keytruda?
- Do I need any blood tests while taking Xalkori?
- How long does it take for Xalkori to work?
- How to pronounce Xalkori?
- What cancers are treated with Xalkori?
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