What condition is Austedo used to treat?
Austedo (deutetrabenazine) is an oral prescription medication approved to treat two conditions: Huntington’s chorea and tardive dyskinesia (TD). Austedo is classified as a vesicular monoamine transporter 2 (VMAT2) inhibitor.
VMAT2 a protein that controls transfer of chemical messengers (neurotransmitters) in the brain between nerves. These neurotransmitters help to control normal body movement or motor function.
In movement disorders such as Huntington's chorea or TD or there can be a problem with the VMAT2 system, leading to uncontrolled body movements. VMAT2 inhibitors block the action of VMAT2, lower neurotransmitter activity, and help to reduce unwanted body movements.
The safety and effectiveness of Austedo in children have not been established.
How well does Austedo work?
Huntington’s chorea is a rare, hereditary, and fatal disorder of nerve cells in the brain. The associated chorea results in involuntary, random, twisting or writhing bodily movements, and occurs in 90% of patients with Huntington's disease.
Tardive dyskinesia (TD) results in involuntary movements, especially in the lower face, that can occur in patients who have taken certain antipsychotic or other neuroleptic medications. These abnormal movements include tongue thrusting, repetitive chewing, jaw swinging and/or facial grimacing. It can occur in other parts of the body, too, such as the hands, feet, legs or torso.
Austedo comes as both an immediate-release and extended-release tablet.
Once-daily Austedo XR has been shown to be therapeutically equivalent to the twice-daily formulation, providing another effective treatment choice.
Other medicines approved to treat tardive dyskinesia include Ingrezza (valbenazine).
This is not all the information you need to know about Austedo (deutetrabenazine) for safe and effective use. Review the full Austedo information here, and discuss this information and any questions you have with your doctor or other health care provider.
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