What is the difference between Flublok and Flublok Quadrivalent?

Drugs.com

Official answer

by Drugs.com

Key Points

  • Flublok Quadrivalent, from Sanofi Pasteur, was first approved by the FDA in 2017 and is used to immunize adults 18 years and older against influenza. Flublok was a recombinant trivalent influenza vaccine first licensed by the FDA in 2013.
  • Flublok has now been replaced by Flublok Quadrivalent, which protects against four influenza strains instead of three.
  • Flublok Quadrivalent was the first high antigen content quadrivalent vaccine and contains three times the active ingredients of other quadrivalent vaccines. It is a recombinant vaccine and does not require an egg-grown vaccine virus nor the use of chicken eggs in production.

    • High antigen content flu vaccines may offer an advantage to people at risk from flu complications, such as seniors or those with lowered immunity. Flublok Quadrivalent has the same purity advantages as trivalent Flublok, containing pure protein made without infectious influenza virus, antibiotics, eggs, thimerosal, preservatives, gelatin or latex.

    Common side effects include injection site reactions (tenderness, pain), headache, fatigue, and muscle and bone pain.

    What is a quadrivalent flu vaccine?

    Quadrivalent vaccines add an additional B strain to the three recommended strains in the trivalent flu vaccine each year, and protect against A and B strains of influenza (4 strains total).

    In general, quadrivalent vaccines have now replaced trivalent vaccines in the U.S. market. Even though quadrivalent or high dose vaccines may give you added protection during the flu season, experts say don't delay getting your influenza vaccine if a particular formulation or brand is not available.

    Do not use Flublok Quadrivalent is you have ever had a severe allergic reaction (for example, anaphylaxis) to any component of the vaccine.

    This is not all the information you need to know about Flublok Quadrivalent for safe and effective use and does not take the place of talking to your doctor about your treatment. Review the full Flublok Quadrivalent information and side effects here, and discuss this information and any questions you have with your doctor or other health care provider.

    Related medical questions

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

    Popular Keywords