Will I need to use Xalkori long term?
Xalkori (crizotinib) is used until your lung cancer, lymphoma or Inflammatory Myofibroblastic Tumor gets worse or you are not able to tolerate the treatment any more due to side effects. Your doctor may also need to change your dose due to side effects.
Xalkori is approved to treat certain types of non-small cell lung cancer that has spread in your body. It will not make your cancer go away, but it may help your cancer to shrink or slow its growth for a certain amount of time.
Xalkori is also approved to treat ALK+ Anaplastic Large Cell Lymphoma (ACLC) in children 1 year of age and older and young adults. ACLC is a rare form of non-Hodgkin lymphoma (NHL). It is used when the cancer has returned (relapsed) or a treatment previously given did not work or is no longer working (refractory).
In July 2022, the FDA approved Xalkori to treat ALK-positive inflammatory myofibroblastic tumors (IMT) in adults and pediatric patients 1 year of age and older. This use is for patients with tumors that cannot be surgically removed, have returned, or when a treatment does not work or is no longer working. These solid tumors commonly occur in the abdomen (stomach) area, pelvis or lungs.
If you have moderate-to-severe liver disease, severe kidney disease, develop certain serious side effects, or take some types of medications (known as strong CYP3A inhibitors) your doctor may need to adjust your dose or how often you take your medicine. Your doctor may also decide you need to stop treatment temporarily or permanently due to certain side effects.
The amount of time you take Xalkori may vary from other patients.
This is not all the information you need to know about Xalkori (crizotinib) for safe and effective use and does not take the place of talking to your doctor about your treatment. Review the full Xalkori information and discuss this information and any questions you have with your doctor or other health care provider.
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